CN100335615C - 转化微生物、d－酰化氨基酸水解酶的制备方法 - Google Patents

转化微生物、d－酰化氨基酸水解酶的制备方法 Download PDF

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Publication number
CN100335615C
CN100335615C CNB008116105A CN00811610A CN100335615C CN 100335615 C CN100335615 C CN 100335615C CN B008116105 A CNB008116105 A CN B008116105A CN 00811610 A CN00811610 A CN 00811610A CN 100335615 C CN100335615 C CN 100335615C
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China
Prior art keywords
amino acid
acid hydrolase
zinc
acylated amino
gene
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Expired - Fee Related
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CNB008116105A
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Chinese (zh)
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CN1514876A (zh
Inventor
竹内贤一
小出芳直
广濑芳彦
森口充瞭
矶部公安
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Amano Enzyme Inc
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Amano Enzyme Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
CNB008116105A 1999-06-17 2000-06-15 转化微生物、d－酰化氨基酸水解酶的制备方法 Expired - Fee Related CN100335615C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP170555/99 1999-06-17
JP170555/1999 1999-06-17
JP17055599A JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、ｄ−アミノアシラーゼの製造方法

Publications (2)

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CN1514876A CN1514876A (zh) 2004-07-21
CN100335615C true CN100335615C (zh) 2007-09-05

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CNB008116105A Expired - Fee Related CN100335615C (zh) 1999-06-17 2000-06-15 转化微生物、d－酰化氨基酸水解酶的制备方法

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US (1) US6943004B1 (https=)
EP (1) EP1188823B1 (https=)
JP (1) JP4327301B2 (https=)
CN (1) CN100335615C (https=)
DE (1) DE60042741D1 (https=)
WO (1) WO2000078926A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020087948A (ko) * 2001-02-01 2002-11-23 미쯔이가가꾸가부시끼가이샤 신규 ｄ-아미노아실라제를 코딩하는 ｄｎａ 및 그것을사용한 ｄ-아미노산의 제조 방법
WO2004055179A1 (ja) * 2002-12-18 2004-07-01 Daiichi Pure Chemicals Co., Ltd. Ｄ−アミノアシラーゼ
EP1435388B1 (en) 2002-12-24 2012-12-12 Daicel Corporation D-aminoacylase mutants from Alcaligenes denitrificans for improved D-amino acid production.
JP4513967B2 (ja) * 2005-03-17 2010-07-28 東洋紡績株式会社 Ｄ−アミノアシラーゼの活性向上方法
JP5334044B2 (ja) * 2008-12-26 2013-11-06 学校法人立命館 Ｄ−アミノアシラーゼ及びそれを用いたｄ−アミノ酸の製造方法
CN108624577B (zh) * 2017-03-22 2021-07-27 中国科学院天津工业生物技术研究所 用于催化n-乙酰-d-色氨酸水解生成d-色氨酸的新酶

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62163689A (ja) * 1986-01-13 1987-07-20 Nagase Seikagaku Kogyo Kk アミノアシラ−ゼ溶液の安定化法
JPH105488A (ja) * 1996-06-21 1998-01-13 Kiyoshi Okamura お茶刈り袋の大型洗濯機

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589386A (en) * 1988-08-26 1996-12-31 Serdar; Cuneyt M. Hydrolysis of cholinesterase inhibitors using parathion hydrolase
JP4063400B2 (ja) * 1997-07-31 2008-03-19 ダイセル化学工業株式会社 Ｄ−アミノアシラーゼ
JPH11318442A (ja) * 1998-03-17 1999-11-24 Daicel Chem Ind Ltd Ｄ―アミノアシラ―ゼ
JP2000041684A (ja) * 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なｄ−アミノアシラーゼおよびその製造方法、並びに該ｄ−アミノアシラーゼを利用したｄ−アミノ酸の製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62163689A (ja) * 1986-01-13 1987-07-20 Nagase Seikagaku Kogyo Kk アミノアシラ−ゼ溶液の安定化法
JPH105488A (ja) * 1996-06-21 1998-01-13 Kiyoshi Okamura お茶刈り袋の大型洗濯機

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cloning and sequencing of a gene encoding Daminoacylasefrom Alcaligenes xylosoxydans subsp andexpression of Wakayama Mkatsuno Y,Biosci Biotechnol Biochem,Vol.59 No.11 1995 *
Eiichi shiiba pruifiaction and characterizatio of l aminoacylasefrom pseudomonas maltophphial B1 MAMORU WAKAKYAMA,J FERMENTATION BIOENGINEERING 1998 *

Also Published As

Publication number Publication date
CN1514876A (zh) 2004-07-21
EP1188823A1 (en) 2002-03-20
EP1188823A4 (en) 2003-01-22
JP2001000185A (ja) 2001-01-09
US6943004B1 (en) 2005-09-13
JP4327301B2 (ja) 2009-09-09
WO2000078926A1 (fr) 2000-12-28
EP1188823B1 (en) 2009-08-12
DE60042741D1 (de) 2009-09-24

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