JP4327301B2 - 形質転換微生物、d−アミノアシラーゼの製造方法 - Google Patents

形質転換微生物、d−アミノアシラーゼの製造方法 Download PDF

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Publication number
JP4327301B2
JP4327301B2 JP17055599A JP17055599A JP4327301B2 JP 4327301 B2 JP4327301 B2 JP 4327301B2 JP 17055599 A JP17055599 A JP 17055599A JP 17055599 A JP17055599 A JP 17055599A JP 4327301 B2 JP4327301 B2 JP 4327301B2
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Prior art keywords
aminoacylase
gene
zinc
producing
medium
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JP17055599A
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English (en)
Japanese (ja)
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JP2001000185A5 (https=
JP2001000185A (ja
Inventor
賢一 竹内
芳直 小出
芳彦 広瀬
充瞭 森口
公安 磯部
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Amano Enzyme Inc
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Amano Enzyme Inc
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Priority to JP17055599A priority Critical patent/JP4327301B2/ja
Application filed by Amano Enzyme Inc filed Critical Amano Enzyme Inc
Priority to US10/009,782 priority patent/US6943004B1/en
Priority to CNB008116105A priority patent/CN100335615C/zh
Priority to PCT/JP2000/003932 priority patent/WO2000078926A1/ja
Priority to DE60042741T priority patent/DE60042741D1/de
Priority to EP00937269A priority patent/EP1188823B1/en
Publication of JP2001000185A publication Critical patent/JP2001000185A/ja
Publication of JP2001000185A5 publication Critical patent/JP2001000185A5/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP17055599A 1999-06-17 1999-06-17 形質転換微生物、d−アミノアシラーゼの製造方法 Expired - Fee Related JP4327301B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP17055599A JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、d−アミノアシラーゼの製造方法
CNB008116105A CN100335615C (zh) 1999-06-17 2000-06-15 转化微生物、d-酰化氨基酸水解酶的制备方法
PCT/JP2000/003932 WO2000078926A1 (fr) 1999-06-17 2000-06-15 Micro-organisme transforme et procede de production de d-aminoacylase
DE60042741T DE60042741D1 (de) 1999-06-17 2000-06-15 Transformierte mikroorganismen und verfahren zur herstellung von d-aminoacylase
US10/009,782 US6943004B1 (en) 1999-06-17 2000-06-15 Transformed microorganism and process for producing D-aminoacylase
EP00937269A EP1188823B1 (en) 1999-06-17 2000-06-15 Transformed microorganism and process for producing d-aminoacylase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17055599A JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、d−アミノアシラーゼの製造方法

Publications (3)

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JP2001000185A JP2001000185A (ja) 2001-01-09
JP2001000185A5 JP2001000185A5 (https=) 2006-05-18
JP4327301B2 true JP4327301B2 (ja) 2009-09-09

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JP17055599A Expired - Fee Related JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、d−アミノアシラーゼの製造方法

Country Status (6)

Country Link
US (1) US6943004B1 (https=)
EP (1) EP1188823B1 (https=)
JP (1) JP4327301B2 (https=)
CN (1) CN100335615C (https=)
DE (1) DE60042741D1 (https=)
WO (1) WO2000078926A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020087948A (ko) * 2001-02-01 2002-11-23 미쯔이가가꾸가부시끼가이샤 신규 d-아미노아실라제를 코딩하는 dna 및 그것을사용한 d-아미노산의 제조 방법
WO2004055179A1 (ja) * 2002-12-18 2004-07-01 Daiichi Pure Chemicals Co., Ltd. D−アミノアシラーゼ
EP1435388B1 (en) 2002-12-24 2012-12-12 Daicel Corporation D-aminoacylase mutants from Alcaligenes denitrificans for improved D-amino acid production.
JP4513967B2 (ja) * 2005-03-17 2010-07-28 東洋紡績株式会社 D−アミノアシラーゼの活性向上方法
JP5334044B2 (ja) * 2008-12-26 2013-11-06 学校法人立命館 D−アミノアシラーゼ及びそれを用いたd−アミノ酸の製造方法
CN108624577B (zh) * 2017-03-22 2021-07-27 中国科学院天津工业生物技术研究所 用于催化n-乙酰-d-色氨酸水解生成d-色氨酸的新酶

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0691820B2 (ja) * 1986-01-13 1994-11-16 ナガセ生化学工業株式会社 アミノアシラ−ゼ溶液の安定化法
US5589386A (en) * 1988-08-26 1996-12-31 Serdar; Cuneyt M. Hydrolysis of cholinesterase inhibitors using parathion hydrolase
JPH105488A (ja) * 1996-06-21 1998-01-13 Kiyoshi Okamura お茶刈り袋の大型洗濯機
JP4063400B2 (ja) * 1997-07-31 2008-03-19 ダイセル化学工業株式会社 D−アミノアシラーゼ
JPH11318442A (ja) * 1998-03-17 1999-11-24 Daicel Chem Ind Ltd D―アミノアシラ―ゼ
JP2000041684A (ja) * 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なd−アミノアシラーゼおよびその製造方法、並びに該d−アミノアシラーゼを利用したd−アミノ酸の製造方法

Also Published As

Publication number Publication date
CN1514876A (zh) 2004-07-21
EP1188823A1 (en) 2002-03-20
EP1188823A4 (en) 2003-01-22
JP2001000185A (ja) 2001-01-09
US6943004B1 (en) 2005-09-13
WO2000078926A1 (fr) 2000-12-28
EP1188823B1 (en) 2009-08-12
DE60042741D1 (de) 2009-09-24
CN100335615C (zh) 2007-09-05

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