CL2019000016A1 - Procesos novedosos para preparar estimuladores de guanilato ciclasa soluble. - Google Patents
Procesos novedosos para preparar estimuladores de guanilato ciclasa soluble.Info
- Publication number
- CL2019000016A1 CL2019000016A1 CL2019000016A CL2019000016A CL2019000016A1 CL 2019000016 A1 CL2019000016 A1 CL 2019000016A1 CL 2019000016 A CL2019000016 A CL 2019000016A CL 2019000016 A CL2019000016 A CL 2019000016A CL 2019000016 A1 CL2019000016 A1 CL 2019000016A1
- Authority
- CL
- Chile
- Prior art keywords
- prepare
- guanylate cyclase
- soluble guanylate
- novel processes
- processes
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000007637 Soluble Guanylyl Cyclase Human genes 0.000 title 1
- 108010007205 Soluble Guanylyl Cyclase Proteins 0.000 title 1
- 239000003119 guanylate cyclase activator Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- AFNJMVYFZNHDRX-UHFFFAOYSA-N [C]1=NC=CC=N1 Chemical class [C]1=NC=CC=N1 AFNJMVYFZNHDRX-UHFFFAOYSA-N 0.000 abstract 1
- 230000001351 cycling effect Effects 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662359453P | 2016-07-07 | 2016-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019000016A1 true CL2019000016A1 (es) | 2019-05-03 |
Family
ID=59416789
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019000016A CL2019000016A1 (es) | 2016-07-07 | 2019-01-04 | Procesos novedosos para preparar estimuladores de guanilato ciclasa soluble. |
| CL2023000228A CL2023000228A1 (es) | 2016-07-07 | 2023-01-24 | Procesos para preparar derivados de 3-(2-pirimidinil) pirazoles |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2023000228A CL2023000228A1 (es) | 2016-07-07 | 2023-01-24 | Procesos para preparar derivados de 3-(2-pirimidinil) pirazoles |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11319308B2 (enExample) |
| EP (2) | EP3481818B1 (enExample) |
| JP (1) | JP7112384B2 (enExample) |
| KR (1) | KR102487872B1 (enExample) |
| CN (1) | CN109563077A (enExample) |
| AU (1) | AU2017291827B2 (enExample) |
| BR (1) | BR112019000291A2 (enExample) |
| CA (1) | CA3029375A1 (enExample) |
| CL (2) | CL2019000016A1 (enExample) |
| EA (1) | EA201990237A1 (enExample) |
| ES (1) | ES2963563T3 (enExample) |
| IL (1) | IL263995B (enExample) |
| MA (1) | MA45603A (enExample) |
| MX (2) | MX389920B (enExample) |
| SG (1) | SG11201900096QA (enExample) |
| WO (1) | WO2018009597A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX382762B (es) | 2016-07-07 | 2025-03-13 | Cyclerion Therapeutics Inc | Procesos novedosos para preparacion de estimuladores de guanilato ciclasa soluble. |
| AU2017291827B2 (en) | 2016-07-07 | 2021-10-21 | Cyclerion Therapeutics, Inc. | Novel processes for preparation of soluble guanylate cyclase stimulators |
| EP4570797A3 (en) | 2018-01-10 | 2025-09-03 | Cyclerion Therapeutics, Inc. | Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
| WO2019161534A1 (en) * | 2018-02-22 | 2019-08-29 | Ironwood Pharmaceuticals, Inc. | Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011150156A2 (en) * | 2010-05-26 | 2011-12-01 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
| JP5860459B2 (ja) | 2010-06-30 | 2016-02-16 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | ｓＧＣ刺激薬 |
| US9139564B2 (en) * | 2011-12-27 | 2015-09-22 | Ironwood Pharmaceuticals, Inc. | 2-benzyl, 3-(pyrimidin-2-yl) substituted pyrazoles useful as sGC stimulators |
| EP2897953B8 (en) * | 2012-09-19 | 2019-06-26 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| RS59981B1 (sr) * | 2013-03-15 | 2020-03-31 | Cyclerion Therapeutics Inc | Sgc stimulatori |
| US20160311826A1 (en) * | 2013-12-11 | 2016-10-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| US20170298055A1 (en) * | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| AU2015317824A1 (en) * | 2014-09-17 | 2017-03-23 | Cyclerion Therapeutics, Inc. | Pyrazole derivatives as sGC stimulators |
| KR20170055531A (ko) * | 2014-09-17 | 2017-05-19 | 아이언우드 파마슈티컬스, 인코포레이티드 | 에스지씨 자극제 |
| US10844064B2 (en) * | 2014-09-17 | 2020-11-24 | Cyclerion Therapeutics, Inc. | sGC stimulators |
| EP3383372B1 (en) * | 2015-11-30 | 2023-11-01 | Cyclerion Therapeutics, Inc. | Solid dispersions comprising a sgc stimulator |
| MX382762B (es) | 2016-07-07 | 2025-03-13 | Cyclerion Therapeutics Inc | Procesos novedosos para preparacion de estimuladores de guanilato ciclasa soluble. |
| JP2019524710A (ja) * | 2016-07-07 | 2019-09-05 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | Ｓｇｃ刺激剤の固体形態 |
| AU2017291827B2 (en) | 2016-07-07 | 2021-10-21 | Cyclerion Therapeutics, Inc. | Novel processes for preparation of soluble guanylate cyclase stimulators |
| EA202091502A1 (ru) * | 2017-12-19 | 2020-11-12 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| EP4570797A3 (en) * | 2018-01-10 | 2025-09-03 | Cyclerion Therapeutics, Inc. | Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators |
-
2017
- 2017-07-06 AU AU2017291827A patent/AU2017291827B2/en active Active
- 2017-07-06 SG SG11201900096QA patent/SG11201900096QA/en unknown
- 2017-07-06 US US16/315,218 patent/US11319308B2/en active Active
- 2017-07-06 KR KR1020197003459A patent/KR102487872B1/ko active Active
- 2017-07-06 CN CN201780047020.6A patent/CN109563077A/zh active Pending
- 2017-07-06 CA CA3029375A patent/CA3029375A1/en active Pending
- 2017-07-06 ES ES17745553T patent/ES2963563T3/es active Active
- 2017-07-06 EA EA201990237A patent/EA201990237A1/ru unknown
- 2017-07-06 EP EP17745553.2A patent/EP3481818B1/en active Active
- 2017-07-06 MX MX2019000105A patent/MX389920B/es unknown
- 2017-07-06 MA MA045603A patent/MA45603A/fr unknown
- 2017-07-06 EP EP23185002.5A patent/EP4249488A3/en active Pending
- 2017-07-06 BR BR112019000291A patent/BR112019000291A2/pt not_active Application Discontinuation
- 2017-07-06 WO PCT/US2017/040810 patent/WO2018009597A1/en not_active Ceased
- 2017-07-06 JP JP2019500355A patent/JP7112384B2/ja active Active
-
2018
- 2018-12-27 IL IL263995A patent/IL263995B/en active IP Right Grant
-
2019
- 2019-01-04 CL CL2019000016A patent/CL2019000016A1/es unknown
- 2019-01-07 MX MX2022001495A patent/MX2022001495A/es unknown
-
2022
- 2022-03-30 US US17/708,296 patent/US11773089B2/en active Active
-
2023
- 2023-01-24 CL CL2023000228A patent/CL2023000228A1/es unknown
- 2023-08-24 US US18/237,435 patent/US20240059684A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017291827A1 (en) | 2019-02-07 |
| SG11201900096QA (en) | 2019-02-27 |
| IL263995A (en) | 2019-02-28 |
| KR20190025986A (ko) | 2019-03-12 |
| BR112019000291A2 (pt) | 2019-04-16 |
| WO2018009597A1 (en) | 2018-01-11 |
| CA3029375A1 (en) | 2018-01-11 |
| MA45603A (fr) | 2019-05-15 |
| CL2023000228A1 (es) | 2023-09-29 |
| US11773089B2 (en) | 2023-10-03 |
| US20240059684A1 (en) | 2024-02-22 |
| MX2022001495A (es) | 2022-03-11 |
| AU2017291827B2 (en) | 2021-10-21 |
| CN109563077A (zh) | 2019-04-02 |
| JP7112384B2 (ja) | 2022-08-03 |
| EP4249488A3 (en) | 2023-12-20 |
| MX389920B (es) | 2025-03-20 |
| EP3481818C0 (en) | 2023-09-06 |
| EP4249488A2 (en) | 2023-09-27 |
| US20220227748A1 (en) | 2022-07-21 |
| US11319308B2 (en) | 2022-05-03 |
| EA201990237A1 (ru) | 2019-08-30 |
| EP3481818B1 (en) | 2023-09-06 |
| IL263995B (en) | 2021-02-28 |
| EP3481818A1 (en) | 2019-05-15 |
| US20210323951A1 (en) | 2021-10-21 |
| ES2963563T3 (es) | 2024-03-27 |
| NZ750123A (en) | 2025-02-28 |
| MX2019000105A (es) | 2019-04-22 |
| JP2019525913A (ja) | 2019-09-12 |
| KR102487872B1 (ko) | 2023-01-12 |
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