CL2016001197A1 - Analisis en hplc de las impurezas en dianhidrogalactitol - Google Patents
Analisis en hplc de las impurezas en dianhidrogalactitolInfo
- Publication number
- CL2016001197A1 CL2016001197A1 CL2016001197A CL2016001197A CL2016001197A1 CL 2016001197 A1 CL2016001197 A1 CL 2016001197A1 CL 2016001197 A CL2016001197 A CL 2016001197A CL 2016001197 A CL2016001197 A CL 2016001197A CL 2016001197 A1 CL2016001197 A1 CL 2016001197A1
- Authority
- CL
- Chile
- Prior art keywords
- dianhydrogalactitol
- impurities
- hplc analysis
- hplc
- analysis
- Prior art date
Links
- AAFJXZWCNVJTMK-GUCUJZIJSA-N (1s,2r)-1-[(2s)-oxiran-2-yl]-2-[(2r)-oxiran-2-yl]ethane-1,2-diol Chemical compound C([C@@H]1[C@H](O)[C@H](O)[C@H]2OC2)O1 AAFJXZWCNVJTMK-GUCUJZIJSA-N 0.000 title 1
- 229950000758 dianhydrogalactitol Drugs 0.000 title 1
- 238000004128 high performance liquid chromatography Methods 0.000 title 1
- 239000012535 impurity Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/8494—Desolvation chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8872—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample impurities
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/083,135 US9029164B2 (en) | 2012-02-27 | 2013-11-18 | Analytical methods for analyzing and determining impurities in dianhydrogalactitol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2016001197A1 true CL2016001197A1 (es) | 2017-06-30 |
Family
ID=53058168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2016001197A CL2016001197A1 (es) | 2013-11-18 | 2016-05-18 | Analisis en hplc de las impurezas en dianhidrogalactitol |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3071555A4 (enExample) |
| JP (1) | JP2016538574A (enExample) |
| KR (1) | KR20160108315A (enExample) |
| CN (1) | CN107529337B (enExample) |
| AU (1) | AU2014348232A1 (enExample) |
| CA (1) | CA2931088A1 (enExample) |
| CL (1) | CL2016001197A1 (enExample) |
| IL (1) | IL245713A0 (enExample) |
| MX (1) | MX2016006457A (enExample) |
| WO (1) | WO2015074025A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106397360A (zh) * | 2015-07-29 | 2017-02-15 | 广西梧州制药(集团)股份有限公司 | 叔丁醇在去水卫矛醇或其组合物冷冻干燥过程中的应用 |
| MX379918B (es) * | 2015-11-25 | 2025-03-11 | Del Mar Pharmaceuticals Bc Ltd | Metodos para analisis y resolucion de preparaciones de dianhidrogalactitol y derivados o analogos del mismo. |
| CN105445407B (zh) * | 2015-12-29 | 2017-04-19 | 成都普思生物科技股份有限公司 | 一种山桐子中脂肪酸和维生素e的检测方法 |
| US10927363B2 (en) | 2016-04-04 | 2021-02-23 | Mie University | DNA sequence and expression vector for alginate lyase |
| KR102270026B1 (ko) * | 2020-01-31 | 2021-06-28 | 현대약품 주식회사 | (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법 |
| CN114113352A (zh) * | 2020-08-28 | 2022-03-01 | 深圳波顿香料有限公司 | 发酵液中内酯型槐糖酯含量的测定方法 |
| US12295919B2 (en) | 2022-03-16 | 2025-05-13 | Mie University | Methods of treatment and prevention using 4-deoxy-L-erythro-5-hexoseulose uronic acid |
| CN120741731B (zh) * | 2025-09-08 | 2025-11-14 | 天津中医药大学 | 一种基于uplc-qtrap-ms/ms检测扶芳藤或复方扶芳藤合剂中化学成分的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04297868A (ja) * | 1991-03-27 | 1992-10-21 | Tonen Corp | オリゴ糖の分析方法 |
| JPH09229920A (ja) * | 1996-02-26 | 1997-09-05 | Kao Corp | グラジェント液体クロマトグラフィー溶離液の処理方法 |
| US6060525A (en) * | 1996-03-01 | 2000-05-09 | Dionix Corporation | Removal of borate in chromatography |
| CA2359337C (en) * | 1999-01-14 | 2005-09-13 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Process for the separation of sugars |
| US20060148732A1 (en) * | 2000-11-17 | 2006-07-06 | Gutterman Jordan U | Inhibition of NF-kappaB by triterpene compositions |
| JP2004294384A (ja) * | 2003-03-28 | 2004-10-21 | National Agriculture & Bio-Oriented Research Organization | 1−デオキシノジリマイシンの測定方法 |
| CA2819769C (en) * | 2003-07-18 | 2016-06-28 | Oakwood Laboratories, L.L.C. | Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions |
| EP1747457B1 (en) * | 2004-05-20 | 2011-11-30 | Novartis AG | Analysis of liquid chromatography eluates |
| JP2008076340A (ja) * | 2006-09-25 | 2008-04-03 | Toppan Printing Co Ltd | 高感度検出方法およびその検出装置 |
| SI2074120T1 (sl) * | 2007-10-25 | 2010-06-30 | Exelixis Inc | Tropan spojine |
| US8772279B2 (en) * | 2010-01-29 | 2014-07-08 | Nerviano Medical Sciences S.R.L. | 6,7-dihydroimidazo[1,5-a]pyrazin-8(5H)-one derivatives as protein kinase modulators |
| AU2011292045B2 (en) * | 2010-08-18 | 2016-03-24 | Del Mar Pharmaceuticals | Method of synthesis of substituted hexitols such as dianhydrogalactitol |
| CN102008541B (zh) * | 2010-10-08 | 2012-07-04 | 广西中医学院 | 无糖型复方扶芳藤制剂中3种主要活性成分的同时检测方法 |
| CN104428664B (zh) * | 2012-02-27 | 2018-09-21 | 德玛医药 | 用于分析和测定在卫康醇中杂质的改良分析方法 |
| BE1020835A5 (nl) * | 2012-03-20 | 2014-06-03 | Maes Francis N V | Werkwijze voor het vervaardigen van een plantenextract, i.h.b. uit desmodium. |
-
2014
- 2014-11-18 EP EP14862051.1A patent/EP3071555A4/en not_active Withdrawn
- 2014-11-18 JP JP2016554543A patent/JP2016538574A/ja active Pending
- 2014-11-18 WO PCT/US2014/066087 patent/WO2015074025A1/en not_active Ceased
- 2014-11-18 KR KR1020167016274A patent/KR20160108315A/ko not_active Withdrawn
- 2014-11-18 CN CN201480073454.XA patent/CN107529337B/zh not_active Expired - Fee Related
- 2014-11-18 CA CA2931088A patent/CA2931088A1/en not_active Abandoned
- 2014-11-18 AU AU2014348232A patent/AU2014348232A1/en not_active Abandoned
- 2014-11-18 MX MX2016006457A patent/MX2016006457A/es unknown
-
2016
- 2016-05-18 CL CL2016001197A patent/CL2016001197A1/es unknown
- 2016-05-18 IL IL245713A patent/IL245713A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL245713A0 (en) | 2016-08-02 |
| AU2014348232A1 (en) | 2016-06-30 |
| KR20160108315A (ko) | 2016-09-19 |
| CN107529337A (zh) | 2017-12-29 |
| JP2016538574A (ja) | 2016-12-08 |
| CN107529337B (zh) | 2021-11-16 |
| WO2015074025A1 (en) | 2015-05-21 |
| MX2016006457A (es) | 2017-01-06 |
| EP3071555A4 (en) | 2017-05-31 |
| CA2931088A1 (en) | 2015-05-21 |
| WO2015074025A9 (en) | 2015-12-17 |
| EP3071555A1 (en) | 2016-09-28 |
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