CL2015003290A1 - Nuevos agonistas del receptor de somatostatina subtipo 4 (sstr4). - Google Patents

Nuevos agonistas del receptor de somatostatina subtipo 4 (sstr4).

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Publication number
CL2015003290A1
CL2015003290A1 CL2015003290A CL2015003290A CL2015003290A1 CL 2015003290 A1 CL2015003290 A1 CL 2015003290A1 CL 2015003290 A CL2015003290 A CL 2015003290A CL 2015003290 A CL2015003290 A CL 2015003290A CL 2015003290 A1 CL2015003290 A1 CL 2015003290A1
Authority
CL
Chile
Prior art keywords
sstr4
receptor subtype
somatostatin receptor
new agonists
agonists
Prior art date
Application number
CL2015003290A
Other languages
English (en)
Spanish (es)
Inventor
Riccardo Giovannini
Henri Doods
Raimund Kuelzer
Iain Lingard
Yunhai Cui
Marco Ferrara
Stefan Just
Rocco Mazzaferro
Klaus Rudolf
Original Assignee
Ct Xion Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Xion Therapeutics Corp filed Critical Ct Xion Therapeutics Corp
Publication of CL2015003290A1 publication Critical patent/CL2015003290A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/423—Oxazoles condensed with carbocyclic rings
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/4965—Non-condensed pyrazines
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    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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CL2015003290A 2013-05-17 2015-11-09 Nuevos agonistas del receptor de somatostatina subtipo 4 (sstr4). CL2015003290A1 (es)

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EP13168224 2013-05-17

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CL2015003290A1 true CL2015003290A1 (es) 2016-06-17

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US (4) US9371282B2 (https=)
EP (1) EP2997021B1 (https=)
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