CL2015000610A1 - Derivados de isoxazolidina - Google Patents

Derivados de isoxazolidina

Info

Publication number
CL2015000610A1
CL2015000610A1 CL2015000610A CL2015000610A CL2015000610A1 CL 2015000610 A1 CL2015000610 A1 CL 2015000610A1 CL 2015000610 A CL2015000610 A CL 2015000610A CL 2015000610 A CL2015000610 A CL 2015000610A CL 2015000610 A1 CL2015000610 A1 CL 2015000610A1
Authority
CL
Chile
Prior art keywords
isoxazolidine
isoxazolidine derivatives
compounds
pharmaceutical composition
derivatives
Prior art date
Application number
CL2015000610A
Other languages
English (en)
Inventor
Eleonora Ghidini
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47044778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015000610(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of CL2015000610A1 publication Critical patent/CL2015000610A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Otolaryngology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

COMPUESTOS GLUCOCORTICOIDES DERIVADOS DE ISOXAZOLIDINA; COMPOSICION FARMACEUTICA QUE COMPRENDE A ESTOS COMPUESTOS; COMBINACION QUE COMPRENDE A ESTOS COMPUESTOS JUNTO A OTROS PRINCIPIOS ACTIVOS; Y DISPOSITIVO QUE COMPRENDE A LA COMPOSICION FARMACEUTICA.
CL2015000610A 2012-09-13 2015-03-12 Derivados de isoxazolidina CL2015000610A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12184286 2012-09-13

Publications (1)

Publication Number Publication Date
CL2015000610A1 true CL2015000610A1 (es) 2015-12-04

Family

ID=47044778

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000610A CL2015000610A1 (es) 2012-09-13 2015-03-12 Derivados de isoxazolidina

Country Status (28)

Country Link
US (2) US9155747B2 (es)
EP (1) EP2895495B1 (es)
JP (2) JP2015533801A (es)
KR (1) KR101719524B1 (es)
CN (2) CN108440637A (es)
AR (1) AR092547A1 (es)
AU (1) AU2013314539B2 (es)
BR (1) BR112015005500B1 (es)
CA (1) CA2884705C (es)
CL (1) CL2015000610A1 (es)
EA (1) EA027034B1 (es)
ES (1) ES2672140T3 (es)
GE (1) GEP201706708B (es)
HK (1) HK1209756A1 (es)
IL (1) IL237686A (es)
MA (1) MA37927B2 (es)
MX (1) MX364865B (es)
MY (1) MY182523A (es)
NZ (1) NZ705902A (es)
PE (1) PE20150675A1 (es)
PH (1) PH12015500534A1 (es)
PL (1) PL2895495T3 (es)
SA (1) SA515360134B1 (es)
SG (1) SG11201501902RA (es)
TN (1) TN2015000093A1 (es)
UA (1) UA116545C2 (es)
WO (1) WO2014040837A1 (es)
ZA (1) ZA201501691B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP201606566B (en) 2011-03-15 2016-11-10 Chiesi Farma Spa Isoxazolidine derivatives
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
WO2019071144A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. USE OF P38 INHIBITORS TO REDUCE DUX4 EXPRESSION
CN115785188B (zh) * 2022-12-20 2024-06-07 湖南科益新生物医药有限公司 一种布地奈德的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL31997A (en) * 1968-05-03 1974-03-14 Lepetit Spa Process for the preparation of pregnano(17alpha,16alpha-d)oxazolines and 16alpha,21-dihydroxy-17alpha-aminopregnanes
SE378110B (es) * 1972-05-19 1975-08-18 Bofors Ab
JPS617293A (ja) * 1984-06-20 1986-01-13 Mitsubishi Chem Ind Ltd 新規なコルチコイド誘導体およびその製法
US5888995A (en) * 1991-02-04 1999-03-30 Astra Aktiebolag Steroid esters
WO2003070745A2 (en) * 2002-02-20 2003-08-28 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
WO2005028495A1 (en) * 2003-09-24 2005-03-31 Glaxo Group Limited Anti-inflammatory glucocorticoids
NO331891B1 (no) * 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
WO2009108118A1 (en) * 2008-02-27 2009-09-03 Astrazeneca Ab 16 alpha, 17 alpa-acetal glucocorticosteroidal derivatives and their use
AU2010294598B2 (en) 2009-09-11 2016-09-01 Chiesi Farmaceutici S.P.A. Pregnane derivatives condensed in the 16, 17 position with an n-substituted isoxazolidine ring as anti-inflammatory agents
TW201139369A (en) 2010-02-05 2011-11-16 Chiesi Farma Spa Pyrrolidine derivatives
CN103380142A (zh) 2011-03-15 2013-10-30 奇斯药制品公司 异噁唑烷衍生物
GEP201606566B (en) * 2011-03-15 2016-11-10 Chiesi Farma Spa Isoxazolidine derivatives
BR112014001932A2 (pt) * 2011-08-01 2017-02-21 Chiesi Farm Spa composto, composição farmacêutica, combinação de um composto e uso de um composto

Also Published As

Publication number Publication date
EA201590390A1 (ru) 2015-08-31
MX2015002898A (es) 2015-06-03
PE20150675A1 (es) 2015-05-20
BR112015005500B1 (pt) 2022-11-22
KR101719524B1 (ko) 2017-03-24
CA2884705C (en) 2021-04-13
PH12015500534B1 (en) 2015-05-04
UA116545C2 (uk) 2018-04-10
US20150376226A1 (en) 2015-12-31
CA2884705A1 (en) 2014-03-20
NZ705902A (en) 2018-04-27
PL2895495T3 (pl) 2018-10-31
HK1209756A1 (en) 2016-04-08
GEP201706708B (en) 2017-07-25
AU2013314539A1 (en) 2015-04-02
MA37927B2 (fr) 2021-08-31
KR20150042264A (ko) 2015-04-20
CN108440637A (zh) 2018-08-24
SA515360134B1 (ar) 2016-07-24
MA20150350A1 (fr) 2015-10-30
US20140069419A1 (en) 2014-03-13
AU2013314539B2 (en) 2018-03-08
US9155747B2 (en) 2015-10-13
MX364865B (es) 2019-05-09
JP2015533801A (ja) 2015-11-26
PH12015500534A1 (en) 2015-05-04
EP2895495A1 (en) 2015-07-22
WO2014040837A1 (en) 2014-03-20
BR112015005500A2 (pt) 2018-05-22
US9469669B2 (en) 2016-10-18
EP2895495B1 (en) 2018-05-16
TN2015000093A1 (en) 2016-06-29
IL237686A (en) 2017-10-31
EA027034B1 (ru) 2017-06-30
ES2672140T3 (es) 2018-06-12
MY182523A (en) 2021-01-25
ZA201501691B (en) 2016-10-26
JP6736607B2 (ja) 2020-08-05
JP2018162270A (ja) 2018-10-18
CN104619714A (zh) 2015-05-13
SG11201501902RA (en) 2015-04-29
AR092547A1 (es) 2015-04-22

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