CL2014001518A1 - Composicion de lagrima artificial porque es una emulsion sin sales que comprende aceite de ricino y un agente seleccionado de polisorbato, carboximetilcelulosa y glicerina, excluyendo aceite de oliva.; una emulsion; y un metodo para aliviar los ojos secos. - Google Patents

Composicion de lagrima artificial porque es una emulsion sin sales que comprende aceite de ricino y un agente seleccionado de polisorbato, carboximetilcelulosa y glicerina, excluyendo aceite de oliva.; una emulsion; y un metodo para aliviar los ojos secos.

Info

Publication number
CL2014001518A1
CL2014001518A1 CL2014001518A CL2014001518A CL2014001518A1 CL 2014001518 A1 CL2014001518 A1 CL 2014001518A1 CL 2014001518 A CL2014001518 A CL 2014001518A CL 2014001518 A CL2014001518 A CL 2014001518A CL 2014001518 A1 CL2014001518 A1 CL 2014001518A1
Authority
CL
Chile
Prior art keywords
emulsion
polysorbate
glycerin
salts
composition
Prior art date
Application number
CL2014001518A
Other languages
English (en)
Spanish (es)
Inventor
Joseph G Vehige
Peter A Simmons
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47459152&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014001518(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CL2014001518A1 publication Critical patent/CL2014001518A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2014001518A 2011-12-07 2014-06-09 Composicion de lagrima artificial porque es una emulsion sin sales que comprende aceite de ricino y un agente seleccionado de polisorbato, carboximetilcelulosa y glicerina, excluyendo aceite de oliva.; una emulsion; y un metodo para aliviar los ojos secos. CL2014001518A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568089P 2011-12-07 2011-12-07
US201261625401P 2012-04-17 2012-04-17

Publications (1)

Publication Number Publication Date
CL2014001518A1 true CL2014001518A1 (es) 2014-10-24

Family

ID=47459152

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014001518A CL2014001518A1 (es) 2011-12-07 2014-06-09 Composicion de lagrima artificial porque es una emulsion sin sales que comprende aceite de ricino y un agente seleccionado de polisorbato, carboximetilcelulosa y glicerina, excluyendo aceite de oliva.; una emulsion; y un metodo para aliviar los ojos secos.

Country Status (27)

Country Link
US (2) US9314528B2 (https=)
EP (5) EP3666257A1 (https=)
JP (1) JP6142419B2 (https=)
KR (1) KR102017922B1 (https=)
CN (2) CN104114152A (https=)
AR (1) AR089123A1 (https=)
AU (2) AU2012347459A1 (https=)
BR (1) BR112014013820A8 (https=)
CA (1) CA2858574C (https=)
CL (1) CL2014001518A1 (https=)
CO (1) CO6990739A2 (https=)
DK (2) DK2787968T3 (https=)
ES (2) ES2896336T3 (https=)
HU (2) HUE057140T2 (https=)
IL (1) IL233008A (https=)
IN (1) IN2014CN04809A (https=)
MX (1) MX355216B (https=)
MY (1) MY173378A (https=)
PH (2) PH12014501296B1 (https=)
PL (2) PL2787969T3 (https=)
PT (2) PT2787968T (https=)
RU (1) RU2014127074A (https=)
SG (1) SG11201403013VA (https=)
SI (2) SI2787968T1 (https=)
TW (1) TWI652072B (https=)
WO (2) WO2013086449A1 (https=)
ZA (1) ZA201404228B (https=)

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US8957048B2 (en) * 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
EP3266446B1 (en) 2016-07-07 2018-11-21 Laboratorios SALVAT, S.A. Ophthalmic composition comprising castor oil and medium chain triglyceride
US11903986B2 (en) 2016-08-19 2024-02-20 Akrivista Llc Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye
CN114376961A (zh) 2017-08-18 2022-04-22 阿克里维斯塔有限责任公司 诊断和治疗干眼综合症的方法和用于治疗人类眼睛的组合物
AU2019261437B2 (en) 2018-04-27 2024-11-07 Allergan, Inc. Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity
WO2025175150A1 (en) * 2024-02-16 2025-08-21 Allergan, Inc. Enhanced artificial tear formulations

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Also Published As

Publication number Publication date
DK2787968T3 (da) 2020-06-02
HK1203057A1 (en) 2015-10-16
IL233008A (en) 2017-07-31
CN104114152A (zh) 2014-10-22
EP4403220A2 (en) 2024-07-24
BR112014013820A2 (pt) 2017-06-13
IL233008A0 (en) 2014-07-31
EP2787969A1 (en) 2014-10-15
WO2013086438A1 (en) 2013-06-13
US20130197083A1 (en) 2013-08-01
ES2896336T3 (es) 2022-02-24
EP3666257A1 (en) 2020-06-17
CA2858574A1 (en) 2013-06-13
EP3981387A1 (en) 2022-04-13
PL2787968T3 (pl) 2020-08-24
CO6990739A2 (es) 2014-07-10
PH12014501296B1 (en) 2023-04-05
PH12014501296A1 (en) 2014-10-08
CN108969482A (zh) 2018-12-11
ZA201404228B (en) 2015-12-23
MY173378A (en) 2020-01-21
AU2017265181B2 (en) 2019-06-20
CA2858574C (en) 2017-05-30
KR20140107383A (ko) 2014-09-04
AR089123A1 (es) 2014-07-30
RU2018119362A3 (https=) 2021-09-07
SI2787968T1 (sl) 2020-08-31
HUE049489T2 (hu) 2020-09-28
PT2787968T (pt) 2020-06-16
EP2787969B1 (en) 2021-09-29
AU2017265181A1 (en) 2017-12-14
HUE057140T2 (hu) 2022-04-28
US9314528B2 (en) 2016-04-19
RU2014127074A (ru) 2016-02-10
KR102017922B1 (ko) 2019-09-03
AU2012347459A1 (en) 2014-07-03
IN2014CN04809A (https=) 2015-09-18
ES2797650T3 (es) 2020-12-03
SI2787969T1 (sl) 2021-12-31
TWI652072B (zh) 2019-03-01
US20130150324A1 (en) 2013-06-13
PT2787969T (pt) 2021-11-09
WO2013086449A1 (en) 2013-06-13
MX355216B (es) 2018-04-10
EP2787968A1 (en) 2014-10-15
HK1201458A1 (en) 2015-09-04
SG11201403013VA (en) 2014-07-30
EP2787968B1 (en) 2020-03-04
DK2787969T3 (da) 2021-11-01
TW201325633A (zh) 2013-07-01
MX2014006804A (es) 2014-09-22
PL2787969T3 (pl) 2021-12-20
JP2015504860A (ja) 2015-02-16
JP6142419B2 (ja) 2017-06-07
PH12021553172A1 (en) 2024-05-27
EP4403220A3 (en) 2024-10-23
RU2018119362A (ru) 2018-11-08
BR112014013820A8 (pt) 2017-06-13

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