CL2009002037A1 - Polinucleotidos codificantes y polipeptidos antigenicos para streptococcus; vector y celula huesped; composición de vacuna; uso para tratar meningitis, otitis media, bacteremia, neumonia o infecciones bacterianas estreptococicas (div. sol. 3100-99) - Google Patents

Polinucleotidos codificantes y polipeptidos antigenicos para streptococcus; vector y celula huesped; composición de vacuna; uso para tratar meningitis, otitis media, bacteremia, neumonia o infecciones bacterianas estreptococicas (div. sol. 3100-99)

Info

Publication number
CL2009002037A1
CL2009002037A1 CL2009002037A CL2009002037A CL2009002037A1 CL 2009002037 A1 CL2009002037 A1 CL 2009002037A1 CL 2009002037 A CL2009002037 A CL 2009002037A CL 2009002037 A CL2009002037 A CL 2009002037A CL 2009002037 A1 CL2009002037 A1 CL 2009002037A1
Authority
CL
Chile
Prior art keywords
bacteremia
div
pneumonia
streptococcus
sol
Prior art date
Application number
CL2009002037A
Other languages
English (en)
Inventor
Denis Martin
Josee Hamel
Bernard R Brodeur
Isabelle Pineau
Clement Rioux
Nathalie Charland
Original Assignee
Id Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22351610&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009002037(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Id Biomedical Corp filed Critical Id Biomedical Corp
Publication of CL2009002037A1 publication Critical patent/CL2009002037A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Polinucleótidos y vectores portadores de ellos que codifican para polipéptidos antigénicos para streptococcus; dichos polipéptidos; polipéptidos quiméricos; composición de vacuna que comprende dichos polipéptidos; y su uso para tratar meningitis, otitis media, bacteremia o neumonía (Div. Sol. 3100-99).
CL2009002037A 1998-12-23 2009-11-05 Polinucleotidos codificantes y polipeptidos antigenicos para streptococcus; vector y celula huesped; composición de vacuna; uso para tratar meningitis, otitis media, bacteremia, neumonia o infecciones bacterianas estreptococicas (div. sol. 3100-99) CL2009002037A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11380098P 1998-12-23 1998-12-23

Publications (1)

Publication Number Publication Date
CL2009002037A1 true CL2009002037A1 (es) 2010-06-25

Family

ID=22351610

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009002037A CL2009002037A1 (es) 1998-12-23 2009-11-05 Polinucleotidos codificantes y polipeptidos antigenicos para streptococcus; vector y celula huesped; composición de vacuna; uso para tratar meningitis, otitis media, bacteremia, neumonia o infecciones bacterianas estreptococicas (div. sol. 3100-99)

Country Status (30)

Country Link
EP (2) EP1141306B1 (es)
JP (2) JP4761623B2 (es)
KR (4) KR101078919B1 (es)
CN (3) CN100398653C (es)
AP (1) AP2001002199A0 (es)
AR (1) AR029322A1 (es)
AT (1) ATE394489T1 (es)
AU (1) AU1764900A (es)
BR (1) BR9916477A (es)
CA (1) CA2356836C (es)
CL (1) CL2009002037A1 (es)
CY (3) CY1108223T1 (es)
CZ (2) CZ303675B6 (es)
DE (1) DE69938670D1 (es)
DK (3) DK1950302T3 (es)
EA (1) EA007409B1 (es)
ES (3) ES2400280T3 (es)
HK (1) HK1118575A1 (es)
HU (1) HU229664B1 (es)
IL (3) IL143905A0 (es)
MX (1) MXPA01006427A (es)
NO (1) NO330800B1 (es)
NZ (1) NZ512574A (es)
OA (1) OA11736A (es)
PL (3) PL206576B1 (es)
PT (3) PT1141306E (es)
TR (2) TR200102497T2 (es)
UY (1) UY25877A1 (es)
WO (1) WO2000039299A2 (es)
ZA (1) ZA200105114B (es)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2505999A (en) 1998-02-20 1999-09-06 Biochem Pharma Inc. Group b streptococcus antigens
EP1801218A3 (en) * 1998-07-27 2007-10-10 Sanofi Pasteur Limited Nucleic acids and proteins from streptococcus pneumoniae
US20030134407A1 (en) 1998-07-27 2003-07-17 Le Page Richard William Falla Nucleic acids and proteins from Streptococcus pneumoniae
EP2050464B1 (en) 1998-12-21 2019-08-07 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
HU229664B1 (en) * 1998-12-23 2014-04-28 Id Biomedical Corp Quebec Streptococcus antigens
WO2001096379A2 (en) 2000-06-12 2001-12-20 University Of Saskatchewan Immunization of dairy cattle with chimeric gapc protein against streptococcus infection
US6833134B2 (en) 2000-06-12 2004-12-21 University Of Saskacthewan Immunization of dairy cattle with GapC protein against Streptococcus infection
US6866855B2 (en) 2000-06-12 2005-03-15 University Of Saskatchewan Immunization of dairy cattle with GapC protein against Streptococcus infection
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
EP1303612A2 (en) 2000-06-20 2003-04-23 Shire Biochem Inc. Streptococcus antigens
AU2002242549A1 (en) * 2001-03-30 2002-10-15 Shire Biochem Inc. Streptococcus pyogenes antigens and corresponding dna fragments
WO2003004650A2 (en) * 2001-07-06 2003-01-16 Shire Biochem Inc. Group b streptococcus antigens and corresponding dna fragments
GB0130228D0 (en) * 2001-12-18 2002-02-06 Hansa Medica Ab Protein
AU2002351623A1 (en) * 2001-12-20 2003-07-09 Shire Biochem Inc. Streptococcus antigens
SI1601770T1 (sl) 2003-03-04 2010-01-29 Intercell Ag Streptococcus pyogenes antigeni
EP2314718A1 (en) 2003-04-15 2011-04-27 Intercell AG S. pneumoniae antigens
NZ569076A (en) 2005-12-22 2011-08-26 Glaxosmithkline Biolog Sa Vaccine comprising capsular polysaccharides conjugates from Streptococcus pneumoniae serotypes 19A and 19F
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
DK2167121T3 (en) 2007-06-26 2015-11-23 Glaxosmithkline Biolog Sa A vaccine comprising Streptococcus pneumoniae kapselpolysaccharidkonjugater
WO2009012588A1 (en) * 2007-07-23 2009-01-29 Sanofi Pasteur Limited Immunogenic polypeptides and monoclonal antibodies
CA2720961A1 (en) * 2008-04-16 2009-10-22 William Ripley Ballou, Jr. Streptococcus pneumonia vaccine
CN102223876A (zh) 2008-09-26 2011-10-19 纳米生物公司 纳米乳剂治疗性组合物及其使用方法
US20120052088A1 (en) 2009-04-30 2012-03-01 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2010132833A1 (en) 2009-05-14 2010-11-18 The Regents Of The University Of Michigan Streptococcus vaccine compositions and methods of using the same
RU2538162C2 (ru) 2009-09-03 2015-01-10 Пфайзер Вэксинс ЭлЭлСи Вакцина против pcsk9
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
JP6046632B2 (ja) 2010-12-03 2016-12-21 サノフィ パストゥール リミテッドSanofi Pasteur Limited 肺炎球菌に対する免疫用組成物
AU2012207088A1 (en) * 2011-01-20 2013-05-02 Children's Medical Center Corporation Vaccines and compositions against Streptococcus pneumoniae
WO2012131504A1 (en) 2011-03-02 2012-10-04 Pfizer Inc. Pcsk9 vaccine
BR112013029514A2 (pt) 2011-05-17 2019-09-24 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, e, método de tratar ou impedir uma doença
MX349494B (es) * 2012-01-05 2017-08-01 Deutsches Krebsforsch Medios y metodos para tratar o diagnosticar canceres positivos a idh1 r132h mutante.
WO2014089706A1 (en) * 2012-12-14 2014-06-19 Sanofi Pasteur, Ltd. Methods for assessing immunogenicity
PT3096783T (pt) 2014-01-21 2021-08-16 Pfizer Polissacáridos capsulares de streptococcus pneumoniae e conjugados dos mesmos
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
ES2820824T3 (es) 2014-01-21 2021-04-22 Pfizer Composiciones inmunogénicas que comprenden antígenos sacáridos capsulares conjugados y usos de las mismas
RU2688831C2 (ru) 2014-01-21 2019-05-22 Пфайзер Инк. Капсульные полисахариды Streptococcus pneumoniae и их конъюгаты
ES2701169T3 (es) 2014-02-14 2019-02-21 Pfizer Conjugados glucoproteicos inmunogénicos
US10653764B2 (en) 2015-01-15 2020-05-19 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
MX2018000867A (es) 2015-07-21 2018-05-15 Pfizer Composiciones inmunogenas que comprenden antigenos de sacarido capsular conjugados, kits que las comprenden y sus usos.
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
JP6884145B2 (ja) 2015-11-20 2021-06-09 ファイザー・インク 肺炎連鎖球菌ワクチンにおいて用いるための免疫原性組成物
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
EP3570879B1 (en) 2017-01-20 2022-03-30 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
US11260119B2 (en) 2018-08-24 2022-03-01 Pfizer Inc. Escherichia coli compositions and methods thereof
CA3120922A1 (en) 2018-12-12 2020-06-18 Pfizer Inc. Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof
JP7239509B6 (ja) 2019-02-22 2023-03-28 ファイザー・インク 細菌多糖類を精製するための方法
US20220184199A1 (en) 2019-04-10 2022-06-16 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
CN114728050A (zh) 2019-07-31 2022-07-08 圣诺菲·帕斯图尔公司 多价肺炎球菌多糖-蛋白质缀合物组合物及其使用方法
IL292494A (en) 2019-11-01 2022-06-01 Pfizer Preparations of Escherichia coli and their methods
WO2021165847A1 (en) 2020-02-21 2021-08-26 Pfizer Inc. Purification of saccharides
CA3173729A1 (en) 2020-02-23 2021-08-26 Pfizer Inc. Escherichia coli compositions and methods thereof
EP4232593A1 (en) 2020-10-22 2023-08-30 Pfizer Inc. Methods for purifying bacterial polysaccharides
PE20231934A1 (es) 2020-10-27 2023-12-01 Pfizer Composiciones de escherichia coli y metodos de las mismas
MX2023005221A (es) 2020-11-04 2023-05-16 Pfizer Composiciones inmunogenicas para uso en vacunas neumococicas.
US20220202923A1 (en) 2020-12-23 2022-06-30 Pfizer Inc. E. coli fimh mutants and uses thereof
EP4333879A1 (en) 2021-05-03 2024-03-13 Pfizer Inc. Vaccination against bacterial and betacoronavirus infections
WO2022234416A1 (en) 2021-05-03 2022-11-10 Pfizer Inc. Vaccination against pneumoccocal and covid-19 infections
EP4346893A2 (en) 2021-05-28 2024-04-10 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
US20220387613A1 (en) 2021-05-28 2022-12-08 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2023135515A1 (en) 2022-01-13 2023-07-20 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2023161817A1 (en) 2022-02-25 2023-08-31 Pfizer Inc. Methods for incorporating azido groups in bacterial capsular polysaccharides
WO2023218322A1 (en) 2022-05-11 2023-11-16 Pfizer Inc. Process for producing of vaccine formulations with preservatives
WO2024084397A1 (en) 2022-10-19 2024-04-25 Pfizer Inc. Vaccination against pneumoccocal and covid-19 infections

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4425437A (en) 1979-11-05 1984-01-10 Genentech, Inc. Microbial polypeptide expression vehicle
US4431739A (en) 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
CA2158658A1 (en) * 1993-03-19 1994-09-29 Margaretha Stalhammar-Carlemalm Protein rib, a cell surface protein that confers immunity to many strains of the group b streptococcus; process for purification of the protein, reagent kit and pharmaceutical composition
AP9701163A0 (en) * 1995-06-07 1998-01-31 Biochem Vaccines Inc Streptococcal heat shock proteins members of the HSP70 family.
US5882896A (en) * 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
US5928895A (en) * 1996-09-24 1999-07-27 Smithkline Beecham Corporation IgA Fc binding protein
EP1400592A1 (en) 1996-10-31 2004-03-24 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
CA2305016A1 (en) * 1997-09-24 1999-04-01 Regents Of The University Of Minnesota Human complement c3-degrading proteinase from streptococcus pneumoniae
AU770378B2 (en) * 1998-04-23 2004-02-19 Uab Research Foundation Pneumococcal surface protein C(PspC), epitopic regions and strain selection thereof, and uses therefor
ATE361365T1 (de) * 1998-07-27 2007-05-15 Sanofi Pasteur Ltd Streptococcus pneumoniae proteine und nukleinsäuren
CN1318103A (zh) * 1998-07-27 2001-10-17 微生物技术有限公司 肺炎链球菌的核酸和蛋白质
IL142017A0 (en) * 1998-09-24 2002-03-10 Univ Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae
EP2050464B1 (en) * 1998-12-21 2019-08-07 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
HU229664B1 (en) * 1998-12-23 2014-04-28 Id Biomedical Corp Quebec Streptococcus antigens

Also Published As

Publication number Publication date
NO20013045L (no) 2001-08-20
CN1191362C (zh) 2005-03-02
CN100398653C (zh) 2008-07-02
CA2356836C (en) 2011-09-13
KR101078919B1 (ko) 2011-11-01
KR20060134227A (ko) 2006-12-27
IL143905A (en) 2011-05-31
PT1141306E (pt) 2008-07-30
MXPA01006427A (es) 2002-06-04
EP2261358A2 (en) 2010-12-15
NO20013045D0 (no) 2001-06-19
HU229664B1 (en) 2014-04-28
PL206576B1 (pl) 2010-08-31
ES2306528T3 (es) 2008-11-01
PL349777A1 (en) 2002-09-09
ES2480417T3 (es) 2014-07-28
TR200102497T2 (tr) 2002-01-21
DK1950302T3 (da) 2013-01-14
CN101134775A (zh) 2008-03-05
NZ512574A (en) 2004-03-26
CY1115340T1 (el) 2017-01-04
CN1332803A (zh) 2002-01-23
AP2001002199A0 (en) 2001-09-30
KR101170203B1 (ko) 2012-07-31
DK2261358T3 (da) 2014-07-28
ATE394489T1 (de) 2008-05-15
CA2356836A1 (en) 2000-07-06
HUP0104774A2 (hu) 2002-04-29
KR20010104693A (ko) 2001-11-26
JP4761623B2 (ja) 2011-08-31
KR100891398B1 (ko) 2009-04-02
KR20100063814A (ko) 2010-06-11
IL194230A0 (en) 2011-08-01
EP1141306A2 (en) 2001-10-10
EP2261358B1 (en) 2014-05-14
DE69938670D1 (de) 2008-06-19
CN1654657A (zh) 2005-08-17
IL194230A (en) 2013-12-31
JP2010142246A (ja) 2010-07-01
EA007409B1 (ru) 2006-10-27
OA11736A (en) 2005-06-12
CY1108223T1 (el) 2014-02-12
AR029322A1 (es) 2003-06-25
PT2261358E (pt) 2014-07-30
EP1141306B1 (en) 2008-05-07
KR100802198B1 (ko) 2008-02-11
JP2002533123A (ja) 2002-10-08
PL205041B1 (pl) 2010-03-31
CZ20012161A3 (cs) 2001-10-17
PL204073B1 (pl) 2009-12-31
HK1118575A1 (en) 2009-02-13
ES2400280T3 (es) 2013-04-08
WO2000039299A3 (en) 2000-11-02
ZA200105114B (en) 2002-11-21
CY1114722T1 (el) 2016-10-05
TR200200633T2 (tr) 2002-06-21
CZ302790B6 (cs) 2011-11-09
HUP0104774A3 (en) 2007-10-29
NO330800B1 (no) 2011-07-18
BR9916477A (pt) 2004-06-22
JP5039802B2 (ja) 2012-10-03
CZ303675B6 (cs) 2013-02-27
IL143905A0 (en) 2002-04-21
AU1764900A (en) 2000-07-31
EA200100565A1 (ru) 2002-04-25
DK1141306T3 (da) 2008-08-18
UY25877A1 (es) 2000-08-21
KR20080036666A (ko) 2008-04-28
PT1950302E (pt) 2013-01-16
WO2000039299A2 (en) 2000-07-06
EP2261358A3 (en) 2011-02-23

Similar Documents

Publication Publication Date Title
CL2009002037A1 (es) Polinucleotidos codificantes y polipeptidos antigenicos para streptococcus; vector y celula huesped; composición de vacuna; uso para tratar meningitis, otitis media, bacteremia, neumonia o infecciones bacterianas estreptococicas (div. sol. 3100-99)
BR0208874A (pt) Proteìnas superficiais de streptococcus pyogenes
NO20004161L (no) Gruppe B streptokoccus antigener
AR033980A1 (es) Antigeno de estreptococos
ATE544776T1 (de) Chimäre dna-bindeproteine
DK1155802T3 (da) Holdeanordning til en form, en formhalvdel eller en formbærer i en spröjtestöbemaskine
FI943389A0 (fi) Bacillus-lajista saatu ksylanaasi, tällaisen ksylanaasin ja muiden proteiinien ekspressiovektori, niiden isäntäorganismit ja käyttö
DE69737125D1 (de) Streptococcus pneumoniae antigene und impfstoffe
CY1106350T1 (el) Εμβολιο φυματιωσης
ATE522541T1 (de) Bakterielle adhäsine konformere
NZ500540A (en) Purified proteins, fusion proteins, recombinant vector, vaccine, kit, comprising proteins from Actinobacillus pleuropneumoniae
ES2146214T3 (es) Vacunas para actinobacillus pleuropneumoniae.
WO1998039450A3 (de) Oberflächenprotein (spsa-protein) von streptococcus pneumoniae deletierte abkömmlinge, expressionssssystem für diese proteine und vaccine mit den proteinen
HUP0104825A2 (hu) Gének, fehérjék és alkalmazásuk
NO922421L (no) Collagenbindende protein, samt fremstilling derav
BR9803296A (pt) Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma.
DK0990703T3 (da) Nyt polypeptid, DNA, som koder herfor, samt anvendelse heraf
DE60224930D1 (de) Expressionsvektoren die signalpeptide aus bakteriophagen kodieren
DE69941099D1 (de) Spezifische Nukleinsäuren und Polypeptide aus krankheitserregenden Stämmen von Neisseria
SE9804491D0 (sv) Novel fibronectin-binding protein
DK0870015T3 (da) Xylanaser, gener, der koder for disse, samt anvendelser deraf
BR0111886A (pt) Antìgeno para estreptococos
Haziroglu et al. Association of Pasteurella haemolytica, Pasteurella multocida and Haemophilus somnus with pneumonia in calves.
ATE547527T1 (de) Gruppe b streptococcus bvh-a2 und bvh-a3 antigene
MX9204348A (es) Vector de adn para la transformacion de celulas de bacillus thuringiensis.