BR9916477A - Polinucleotìdeo isolado, polinucleotìdeo quimérico, composição de vacina e uso desta composição compreendendo os polinucleotìdeos - Google Patents
Polinucleotìdeo isolado, polinucleotìdeo quimérico, composição de vacina e uso desta composição compreendendo os polinucleotìdeosInfo
- Publication number
- BR9916477A BR9916477A BR9916477-9A BR9916477A BR9916477A BR 9916477 A BR9916477 A BR 9916477A BR 9916477 A BR9916477 A BR 9916477A BR 9916477 A BR9916477 A BR 9916477A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- polynucleotide
- polynucleotides
- vaccine
- disclosed
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 5
- 108091033319 polynucleotide Proteins 0.000 title abstract 5
- 239000002157 polynucleotide Substances 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 241000194017 Streptococcus Species 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11380098P | 1998-12-23 | 1998-12-23 | |
PCT/CA1999/001218 WO2000039299A2 (en) | 1998-12-23 | 1999-12-20 | Streptococcus antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9916477A true BR9916477A (pt) | 2004-06-22 |
Family
ID=22351610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9916477-9A BR9916477A (pt) | 1998-12-23 | 1999-12-20 | Polinucleotìdeo isolado, polinucleotìdeo quimérico, composição de vacina e uso desta composição compreendendo os polinucleotìdeos |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP1141306B1 (pt) |
JP (2) | JP4761623B2 (pt) |
KR (4) | KR101078919B1 (pt) |
CN (3) | CN100398653C (pt) |
AP (1) | AP2001002199A0 (pt) |
AR (1) | AR029322A1 (pt) |
AT (1) | ATE394489T1 (pt) |
AU (1) | AU1764900A (pt) |
BR (1) | BR9916477A (pt) |
CA (1) | CA2356836C (pt) |
CL (1) | CL2009002037A1 (pt) |
CY (3) | CY1108223T1 (pt) |
CZ (2) | CZ303675B6 (pt) |
DE (1) | DE69938670D1 (pt) |
DK (3) | DK1950302T3 (pt) |
EA (1) | EA007409B1 (pt) |
ES (3) | ES2400280T3 (pt) |
HK (1) | HK1118575A1 (pt) |
HU (1) | HU229664B1 (pt) |
IL (3) | IL143905A0 (pt) |
MX (1) | MXPA01006427A (pt) |
NO (1) | NO330800B1 (pt) |
NZ (1) | NZ512574A (pt) |
OA (1) | OA11736A (pt) |
PL (3) | PL206576B1 (pt) |
PT (3) | PT1141306E (pt) |
TR (2) | TR200102497T2 (pt) |
UY (1) | UY25877A1 (pt) |
WO (1) | WO2000039299A2 (pt) |
ZA (1) | ZA200105114B (pt) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2505999A (en) | 1998-02-20 | 1999-09-06 | Biochem Pharma Inc. | Group b streptococcus antigens |
EP1801218A3 (en) * | 1998-07-27 | 2007-10-10 | Sanofi Pasteur Limited | Nucleic acids and proteins from streptococcus pneumoniae |
US20030134407A1 (en) | 1998-07-27 | 2003-07-17 | Le Page Richard William Falla | Nucleic acids and proteins from Streptococcus pneumoniae |
EP2050464B1 (en) | 1998-12-21 | 2019-08-07 | Medimmune, Inc. | Streptococcus pneumoniae proteins and immunogenic fragments for vaccines |
US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
HU229664B1 (en) * | 1998-12-23 | 2014-04-28 | Id Biomedical Corp Quebec | Streptococcus antigens |
WO2001096379A2 (en) | 2000-06-12 | 2001-12-20 | University Of Saskatchewan | Immunization of dairy cattle with chimeric gapc protein against streptococcus infection |
US6833134B2 (en) | 2000-06-12 | 2004-12-21 | University Of Saskacthewan | Immunization of dairy cattle with GapC protein against Streptococcus infection |
US6866855B2 (en) | 2000-06-12 | 2005-03-15 | University Of Saskatchewan | Immunization of dairy cattle with GapC protein against Streptococcus infection |
US7074415B2 (en) | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
EP1303612A2 (en) | 2000-06-20 | 2003-04-23 | Shire Biochem Inc. | Streptococcus antigens |
AU2002242549A1 (en) * | 2001-03-30 | 2002-10-15 | Shire Biochem Inc. | Streptococcus pyogenes antigens and corresponding dna fragments |
WO2003004650A2 (en) * | 2001-07-06 | 2003-01-16 | Shire Biochem Inc. | Group b streptococcus antigens and corresponding dna fragments |
GB0130228D0 (en) * | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
AU2002351623A1 (en) * | 2001-12-20 | 2003-07-09 | Shire Biochem Inc. | Streptococcus antigens |
SI1601770T1 (sl) | 2003-03-04 | 2010-01-29 | Intercell Ag | Streptococcus pyogenes antigeni |
EP2314718A1 (en) | 2003-04-15 | 2011-04-27 | Intercell AG | S. pneumoniae antigens |
NZ569076A (en) | 2005-12-22 | 2011-08-26 | Glaxosmithkline Biolog Sa | Vaccine comprising capsular polysaccharides conjugates from Streptococcus pneumoniae serotypes 19A and 19F |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
DK2167121T3 (en) | 2007-06-26 | 2015-11-23 | Glaxosmithkline Biolog Sa | A vaccine comprising Streptococcus pneumoniae kapselpolysaccharidkonjugater |
WO2009012588A1 (en) * | 2007-07-23 | 2009-01-29 | Sanofi Pasteur Limited | Immunogenic polypeptides and monoclonal antibodies |
CA2720961A1 (en) * | 2008-04-16 | 2009-10-22 | William Ripley Ballou, Jr. | Streptococcus pneumonia vaccine |
CN102223876A (zh) | 2008-09-26 | 2011-10-19 | 纳米生物公司 | 纳米乳剂治疗性组合物及其使用方法 |
US20120052088A1 (en) | 2009-04-30 | 2012-03-01 | Coley Pharmaceutical Group, Inc. | Pneumococcal vaccine and uses thereof |
WO2010132833A1 (en) | 2009-05-14 | 2010-11-18 | The Regents Of The University Of Michigan | Streptococcus vaccine compositions and methods of using the same |
RU2538162C2 (ru) | 2009-09-03 | 2015-01-10 | Пфайзер Вэксинс ЭлЭлСи | Вакцина против pcsk9 |
GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
JP6046632B2 (ja) | 2010-12-03 | 2016-12-21 | サノフィ パストゥール リミテッドSanofi Pasteur Limited | 肺炎球菌に対する免疫用組成物 |
AU2012207088A1 (en) * | 2011-01-20 | 2013-05-02 | Children's Medical Center Corporation | Vaccines and compositions against Streptococcus pneumoniae |
WO2012131504A1 (en) | 2011-03-02 | 2012-10-04 | Pfizer Inc. | Pcsk9 vaccine |
BR112013029514A2 (pt) | 2011-05-17 | 2019-09-24 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, e, método de tratar ou impedir uma doença |
MX349494B (es) * | 2012-01-05 | 2017-08-01 | Deutsches Krebsforsch | Medios y metodos para tratar o diagnosticar canceres positivos a idh1 r132h mutante. |
WO2014089706A1 (en) * | 2012-12-14 | 2014-06-19 | Sanofi Pasteur, Ltd. | Methods for assessing immunogenicity |
PT3096783T (pt) | 2014-01-21 | 2021-08-16 | Pfizer | Polissacáridos capsulares de streptococcus pneumoniae e conjugados dos mesmos |
US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
ES2820824T3 (es) | 2014-01-21 | 2021-04-22 | Pfizer | Composiciones inmunogénicas que comprenden antígenos sacáridos capsulares conjugados y usos de las mismas |
RU2688831C2 (ru) | 2014-01-21 | 2019-05-22 | Пфайзер Инк. | Капсульные полисахариды Streptococcus pneumoniae и их конъюгаты |
ES2701169T3 (es) | 2014-02-14 | 2019-02-21 | Pfizer | Conjugados glucoproteicos inmunogénicos |
US10653764B2 (en) | 2015-01-15 | 2020-05-19 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
MX2018000867A (es) | 2015-07-21 | 2018-05-15 | Pfizer | Composiciones inmunogenas que comprenden antigenos de sacarido capsular conjugados, kits que las comprenden y sus usos. |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
JP6884145B2 (ja) | 2015-11-20 | 2021-06-09 | ファイザー・インク | 肺炎連鎖球菌ワクチンにおいて用いるための免疫原性組成物 |
GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
EP3570879B1 (en) | 2017-01-20 | 2022-03-30 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
CA3120922A1 (en) | 2018-12-12 | 2020-06-18 | Pfizer Inc. | Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof |
JP7239509B6 (ja) | 2019-02-22 | 2023-03-28 | ファイザー・インク | 細菌多糖類を精製するための方法 |
US20220184199A1 (en) | 2019-04-10 | 2022-06-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
CN114728050A (zh) | 2019-07-31 | 2022-07-08 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物及其使用方法 |
IL292494A (en) | 2019-11-01 | 2022-06-01 | Pfizer | Preparations of Escherichia coli and their methods |
WO2021165847A1 (en) | 2020-02-21 | 2021-08-26 | Pfizer Inc. | Purification of saccharides |
CA3173729A1 (en) | 2020-02-23 | 2021-08-26 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
EP4232593A1 (en) | 2020-10-22 | 2023-08-30 | Pfizer Inc. | Methods for purifying bacterial polysaccharides |
PE20231934A1 (es) | 2020-10-27 | 2023-12-01 | Pfizer | Composiciones de escherichia coli y metodos de las mismas |
MX2023005221A (es) | 2020-11-04 | 2023-05-16 | Pfizer | Composiciones inmunogenicas para uso en vacunas neumococicas. |
US20220202923A1 (en) | 2020-12-23 | 2022-06-30 | Pfizer Inc. | E. coli fimh mutants and uses thereof |
EP4333879A1 (en) | 2021-05-03 | 2024-03-13 | Pfizer Inc. | Vaccination against bacterial and betacoronavirus infections |
WO2022234416A1 (en) | 2021-05-03 | 2022-11-10 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
EP4346893A2 (en) | 2021-05-28 | 2024-04-10 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
US20220387613A1 (en) | 2021-05-28 | 2022-12-08 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
WO2023135515A1 (en) | 2022-01-13 | 2023-07-20 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
WO2023161817A1 (en) | 2022-02-25 | 2023-08-31 | Pfizer Inc. | Methods for incorporating azido groups in bacterial capsular polysaccharides |
WO2023218322A1 (en) | 2022-05-11 | 2023-11-16 | Pfizer Inc. | Process for producing of vaccine formulations with preservatives |
WO2024084397A1 (en) | 2022-10-19 | 2024-04-25 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
CA2158658A1 (en) * | 1993-03-19 | 1994-09-29 | Margaretha Stalhammar-Carlemalm | Protein rib, a cell surface protein that confers immunity to many strains of the group b streptococcus; process for purification of the protein, reagent kit and pharmaceutical composition |
AP9701163A0 (en) * | 1995-06-07 | 1998-01-31 | Biochem Vaccines Inc | Streptococcal heat shock proteins members of the HSP70 family. |
US5882896A (en) * | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | M protein |
US5928895A (en) * | 1996-09-24 | 1999-07-27 | Smithkline Beecham Corporation | IgA Fc binding protein |
EP1400592A1 (en) | 1996-10-31 | 2004-03-24 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
CA2305016A1 (en) * | 1997-09-24 | 1999-04-01 | Regents Of The University Of Minnesota | Human complement c3-degrading proteinase from streptococcus pneumoniae |
AU770378B2 (en) * | 1998-04-23 | 2004-02-19 | Uab Research Foundation | Pneumococcal surface protein C(PspC), epitopic regions and strain selection thereof, and uses therefor |
ATE361365T1 (de) * | 1998-07-27 | 2007-05-15 | Sanofi Pasteur Ltd | Streptococcus pneumoniae proteine und nukleinsäuren |
CN1318103A (zh) * | 1998-07-27 | 2001-10-17 | 微生物技术有限公司 | 肺炎链球菌的核酸和蛋白质 |
IL142017A0 (en) * | 1998-09-24 | 2002-03-10 | Univ Minnesota | Human complement c3-degrading polypeptide from streptococcus pneumoniae |
EP2050464B1 (en) * | 1998-12-21 | 2019-08-07 | Medimmune, Inc. | Streptococcus pneumoniae proteins and immunogenic fragments for vaccines |
HU229664B1 (en) * | 1998-12-23 | 2014-04-28 | Id Biomedical Corp Quebec | Streptococcus antigens |
-
1999
- 1999-12-20 HU HU0104774A patent/HU229664B1/hu not_active IP Right Cessation
- 1999-12-20 PL PL349777A patent/PL206576B1/pl unknown
- 1999-12-20 PL PL382438A patent/PL204073B1/pl not_active IP Right Cessation
- 1999-12-20 CN CNB2005100037492A patent/CN100398653C/zh not_active Expired - Fee Related
- 1999-12-20 AU AU17649/00A patent/AU1764900A/en not_active Abandoned
- 1999-12-20 DK DK08155317.4T patent/DK1950302T3/da active
- 1999-12-20 ES ES08155317T patent/ES2400280T3/es not_active Expired - Lifetime
- 1999-12-20 CN CNA2007101481600A patent/CN101134775A/zh active Pending
- 1999-12-20 AT AT99960748T patent/ATE394489T1/de active
- 1999-12-20 CZ CZ20012161A patent/CZ303675B6/cs not_active IP Right Cessation
- 1999-12-20 ES ES10180372.4T patent/ES2480417T3/es not_active Expired - Lifetime
- 1999-12-20 EA EA200100565A patent/EA007409B1/ru not_active IP Right Cessation
- 1999-12-20 PT PT99960748T patent/PT1141306E/pt unknown
- 1999-12-20 DE DE69938670T patent/DE69938670D1/de not_active Expired - Lifetime
- 1999-12-20 CN CNB998149047A patent/CN1191362C/zh not_active Expired - Fee Related
- 1999-12-20 DK DK99960748T patent/DK1141306T3/da active
- 1999-12-20 AP APAP/P/2001/002199A patent/AP2001002199A0/en unknown
- 1999-12-20 BR BR9916477-9A patent/BR9916477A/pt active Search and Examination
- 1999-12-20 JP JP2000591190A patent/JP4761623B2/ja not_active Expired - Fee Related
- 1999-12-20 OA OA1200100165A patent/OA11736A/en unknown
- 1999-12-20 NZ NZ512574A patent/NZ512574A/xx not_active IP Right Cessation
- 1999-12-20 MX MXPA01006427A patent/MXPA01006427A/es not_active IP Right Cessation
- 1999-12-20 PT PT101803724T patent/PT2261358E/pt unknown
- 1999-12-20 WO PCT/CA1999/001218 patent/WO2000039299A2/en active Application Filing
- 1999-12-20 PT PT81553174T patent/PT1950302E/pt unknown
- 1999-12-20 CZ CZ20100674A patent/CZ302790B6/cs not_active IP Right Cessation
- 1999-12-20 KR KR1020107009285A patent/KR101078919B1/ko not_active IP Right Cessation
- 1999-12-20 ES ES99960748T patent/ES2306528T3/es not_active Expired - Lifetime
- 1999-12-20 PL PL382437A patent/PL205041B1/pl unknown
- 1999-12-20 CA CA2356836A patent/CA2356836C/en not_active Expired - Fee Related
- 1999-12-20 KR KR1020067025282A patent/KR100891398B1/ko not_active IP Right Cessation
- 1999-12-20 TR TR2001/02497T patent/TR200102497T2/xx unknown
- 1999-12-20 KR KR1020017007963A patent/KR100802198B1/ko not_active IP Right Cessation
- 1999-12-20 TR TR2002/00633T patent/TR200200633T2/xx unknown
- 1999-12-20 KR KR1020087008264A patent/KR101170203B1/ko not_active IP Right Cessation
- 1999-12-20 EP EP99960748A patent/EP1141306B1/en not_active Expired - Lifetime
- 1999-12-20 IL IL14390599A patent/IL143905A0/xx unknown
- 1999-12-20 DK DK10180372.4T patent/DK2261358T3/da active
- 1999-12-20 EP EP10180372.4A patent/EP2261358B1/en not_active Expired - Lifetime
- 1999-12-23 UY UY25877A patent/UY25877A1/es unknown
- 1999-12-23 AR ARP990106746A patent/AR029322A1/es not_active Application Discontinuation
-
2001
- 2001-06-19 NO NO20013045A patent/NO330800B1/no not_active IP Right Cessation
- 2001-06-21 IL IL143905A patent/IL143905A/en not_active IP Right Cessation
- 2001-06-21 ZA ZA200105114A patent/ZA200105114B/en unknown
-
2008
- 2008-07-29 CY CY20081100787T patent/CY1108223T1/el unknown
- 2008-09-10 HK HK08110047.4A patent/HK1118575A1/xx not_active IP Right Cessation
- 2008-09-21 IL IL194230A patent/IL194230A/en not_active IP Right Cessation
-
2009
- 2009-11-05 CL CL2009002037A patent/CL2009002037A1/es unknown
-
2010
- 2010-02-09 JP JP2010026521A patent/JP5039802B2/ja not_active Expired - Fee Related
-
2012
- 2012-12-27 CY CY20121101268T patent/CY1114722T1/el unknown
-
2014
- 2014-07-16 CY CY20141100536T patent/CY1115340T1/el unknown
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