BR9803296A - Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma. - Google Patents
Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma.Info
- Publication number
- BR9803296A BR9803296A BR9803296-8A BR9803296A BR9803296A BR 9803296 A BR9803296 A BR 9803296A BR 9803296 A BR9803296 A BR 9803296A BR 9803296 A BR9803296 A BR 9803296A
- Authority
- BR
- Brazil
- Prior art keywords
- molecule
- fas
- antibody
- treatment
- prophylaxis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MOLéCULA, ANTICORPO, USO DE UMA MOLéCULA, DNA, VETOR DE DNA RECOMBINANTE, CéLULA HOSPEDEIRA, MICROORGANISMO, PROCESSO PARA PRODUZIR UM ANTICORPO, AGENTE PARA O TRATAMENTO OU PROFILAXIA DE CONDIçõES ATRIBUìVEIS A ANORMALIDADES DO SISTEMA LIGANDO FAS/FAS, USO DE UMA MOLéCULA E HIBRIDOMA". Anticorpos Fas anti-humanos que são reativos cruzados com Fas de camundongo e humano são utilizáveis no tratamento de condições atribuíveis a anormalidades no sistema ligando Fas/Fas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8295397 | 1997-04-01 | ||
JP16908897 | 1997-06-25 | ||
JP27606497 | 1997-10-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9803296A true BR9803296A (pt) | 2000-01-11 |
Family
ID=27304060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9803296-8A BR9803296A (pt) | 1997-04-01 | 1998-04-01 | Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0909816A1 (pt) |
KR (1) | KR19980080993A (pt) |
CN (1) | CN1207395A (pt) |
AR (1) | AR010139A1 (pt) |
AU (1) | AU734758B2 (pt) |
BR (1) | BR9803296A (pt) |
CA (1) | CA2233783A1 (pt) |
CZ (1) | CZ294340B6 (pt) |
HU (1) | HUP9800744A3 (pt) |
ID (1) | ID20117A (pt) |
IL (1) | IL123888A0 (pt) |
NO (1) | NO981454L (pt) |
NZ (1) | NZ330095A (pt) |
PL (1) | PL325667A1 (pt) |
RU (1) | RU2212412C2 (pt) |
TR (1) | TR199800604A2 (pt) |
TW (1) | TW526205B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6972323B1 (en) | 1997-04-01 | 2005-12-06 | Sankyo Company, Limited | Anti-Fas antibodies |
ATE357459T1 (de) * | 1998-01-23 | 2007-04-15 | Hoffmann La Roche | Antikörper gegen mensliches il-12 |
EP1087993B1 (en) | 1998-06-18 | 2008-04-02 | Imed Ab | Fas peptides and antibodies for modulating apoptosis |
AU757961B2 (en) * | 1998-09-30 | 2003-03-13 | Sankyo Company Limited | Anti-Fas antibodies |
HUP0201333A3 (en) | 1999-05-24 | 2004-11-29 | Sankyo Company Ltd Chuo Ku | Medicinal compositions containing anti-fas antibody |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US20070129291A1 (en) * | 2001-08-01 | 2007-06-07 | Genset S.A. | Genobix agonists and antagonists for use in the treatment of metabolic disorders |
JP2005509412A (ja) | 2001-08-23 | 2005-04-14 | アールエスアール リミテッド | チロトロフィン(tsh)受容体の抗原決定領域、その使用およびその抗体 |
ES2357225T3 (es) | 2001-11-01 | 2011-04-20 | Uab Research Foundation | Combinaciones de anticuerpos anti-dr5 y anticuerpos anti-dr4 y otros agentes terapéuticos. |
HUE026132T2 (en) | 2004-01-07 | 2016-05-30 | Novartis Vaccines & Diagnostics Inc | M-CSF-specific monoclonal antibody and its uses |
CN102170905B (zh) * | 2008-08-01 | 2016-08-03 | 阿克西斯股份有限公司 | 骨关节炎治疗剂及预防剂 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0723556A4 (en) * | 1993-10-14 | 2003-03-19 | Immunex Corp | FAS ANTAGONISTS AND THEIR APPLICATIONS |
DE69535719T2 (de) * | 1994-01-07 | 2009-03-19 | Mochida Pharmaceutical Co. Ltd. | Fas-antigenbindender ligand |
AU6091496A (en) * | 1995-06-07 | 1996-12-30 | Chiron Corporation | Antibodies to fas antigen capable of inhibiting apoptosis |
GB9523469D0 (en) * | 1995-11-16 | 1996-01-17 | Sandoz Ltd | Organic compounds |
-
1998
- 1998-03-30 AU AU59701/98A patent/AU734758B2/en not_active Ceased
- 1998-03-30 IL IL12388898A patent/IL123888A0/xx unknown
- 1998-03-31 TW TW087104806A patent/TW526205B/zh not_active IP Right Cessation
- 1998-03-31 CA CA002233783A patent/CA2233783A1/en not_active Abandoned
- 1998-03-31 ID IDP980478A patent/ID20117A/id unknown
- 1998-03-31 NO NO981454A patent/NO981454L/no not_active Application Discontinuation
- 1998-03-31 RU RU98105631/13A patent/RU2212412C2/ru not_active IP Right Cessation
- 1998-03-31 NZ NZ330095A patent/NZ330095A/xx unknown
- 1998-04-01 CZ CZ1998985A patent/CZ294340B6/cs not_active IP Right Cessation
- 1998-04-01 PL PL98325667A patent/PL325667A1/xx unknown
- 1998-04-01 HU HU9800744A patent/HUP9800744A3/hu unknown
- 1998-04-01 TR TR1998/00604A patent/TR199800604A2/xx unknown
- 1998-04-01 EP EP98302575A patent/EP0909816A1/en not_active Withdrawn
- 1998-04-01 BR BR9803296-8A patent/BR9803296A/pt not_active IP Right Cessation
- 1998-04-01 CN CN98108265A patent/CN1207395A/zh active Pending
- 1998-04-01 AR ARP980101481A patent/AR010139A1/es unknown
- 1998-04-01 KR KR1019980011477A patent/KR19980080993A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TR199800604A3 (tr) | 1999-10-21 |
AU5970198A (en) | 1998-10-08 |
RU2212412C2 (ru) | 2003-09-20 |
CN1207395A (zh) | 1999-02-10 |
HUP9800744A3 (en) | 2001-04-28 |
CZ98598A3 (cs) | 1998-10-14 |
CZ294340B6 (cs) | 2004-12-15 |
PL325667A1 (en) | 1998-10-12 |
AU734758B2 (en) | 2001-06-21 |
EP0909816A1 (en) | 1999-04-21 |
NO981454D0 (no) | 1998-03-31 |
HU9800744D0 (en) | 1998-05-28 |
CA2233783A1 (en) | 1998-10-01 |
IL123888A0 (en) | 1998-10-30 |
HUP9800744A2 (hu) | 1999-02-01 |
NZ330095A (en) | 1998-12-23 |
KR19980080993A (ko) | 1998-11-25 |
TW526205B (en) | 2003-04-01 |
ID20117A (id) | 1998-10-01 |
AR010139A1 (es) | 2000-05-17 |
TR199800604A2 (xx) | 1999-10-21 |
NO981454L (no) | 1998-10-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9713294A (pt) | "anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano" | |
CL2009000575A1 (es) | Anticuerpos aislados anti-interleuquina 12 (anti il-12) de mamiferos, secuencia de nucleotidos, vector, celula y metodo de produccion, composicion y dispositivo medico que contienen, util en el diagnostico y tratamiento de condicones relacionadas con il-12. | |
BR9803296A (pt) | Moléculam anticorpo,uso de uma molécula, dna, vetor de dna recombinante, célula hospedeira,microorganismo, processo para produzir um anticorpo agente para o tratamento ou profilaxia de condições atribuìveis a normalidades do sistema ligando fas/fas, uso de uma molécula e hibridoma. | |
ATE248605T1 (de) | Für e-selectin und p-selectin spezifische kreuzreaktive monoklonale antikörper | |
DE69227041D1 (de) | Expression und reinigung von rekombinantem, löslichem gewebefaktor | |
DE69534235D1 (de) | Cytokin lerk-7 | |
ATE312920T1 (de) | Dna immunisierung gegen chlamydia infektion | |
BR9808153A (pt) | Processo para melhorar a fotossìntese | |
CY1109437T1 (el) | ΣΥΝΘΕΣΕΙΣ β-ΓΛΥΚΑΝΩΝ ΚΑΙ ΕΙΔΙΚΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ | |
KR950032279A (ko) | 인체의 프로그램된 세포 사멸과 관련 있는 펩티드 및 이를 암호하는 디엔에이(dna) | |
BR0212756A (pt) | Molécula de anticorpo tendo especificidade para kdr humano, variante da molécula de anticorpo, composto, sequência de dna, vetor, célula hospedeira, processo para a produção da molécula de anticorpo, composição terapêutica ou diagnóstica, e, uso da molécula de anticorpo | |
BRPI0504146A (pt) | processo catalìtico seletivo regenerativo | |
BR9904475A (pt) | Molécula tipo anticorpo anti-fas, humanizada, agente para a profilaxia e/ou tratamento de condições envolvendo uma anormalidade no sistema ligando fas/fas, uso de um anticorpo, dna, vetor de dna recombinante, célula hospedeira, processo para produzir um anticorpo anti-pas, cepa transformante de e.coli, e, polipeptìdeo. | |
BR9608481A (pt) | Anticorpos quiméricos para administração de antìgenos a células selecionadas do sistema imunológico. | |
AR036189A1 (es) | Anticuerpos de interleuquina-1beta | |
BR0013043A (pt) | Proteìna isolada, anticorpo isolado, composição, método de regulação de reação imunológica em animais, método de tratamento de câncer em animais, molécula de ácido nucleico isolado, molécula de ácido nucleico recombinante, célula recombinante e vìrus recombinante | |
BR0015287A (pt) | Moléculas recombinantes de fusão | |
DK0457804T3 (da) | M-CSF-monoklonale antistoffer, som genkender en neutraliserende, konformational epitop | |
DE69841331D1 (de) | Humanisierte monoklonale antikörper die schützen gegen shigatoxininduzierte krankheiten | |
DE69938725D1 (de) | Monoklonale antikörper gegen das protein g3bp und deren verwendungen | |
DE69940692D1 (de) | Verwendung von immunogenen immunsuppressiven und/oder angiogenen proteinen die inaktiviert sind, verfahren zur deren herstellung, und verwendungen als pharmazeutikum oder impfstoff | |
BR9101117A (pt) | Produto que compreende um ou mais veiculos de material enzimatico e processo para distribuir um agente ativo a um sitio | |
ATE98130T1 (de) | Kombination von angiotensin-converting-enzymehemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln. | |
DE69839582D1 (de) | Neues polypeptid, dafür kodierende dna und deren verwendungen | |
Beletskij et al. | A parametric analysis of relative equilibrium stability in a gravitational field. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 8A E 9A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007. |