CH688572A5 - Procédé pour la préparation à sec de particules, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telle particules. - Google Patents

Procédé pour la préparation à sec de particules, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telle particules. Download PDF

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Publication number
CH688572A5
CH688572A5 CH01436/94A CH143694A CH688572A5 CH 688572 A5 CH688572 A5 CH 688572A5 CH 01436/94 A CH01436/94 A CH 01436/94A CH 143694 A CH143694 A CH 143694A CH 688572 A5 CH688572 A5 CH 688572A5
Authority
CH
Switzerland
Prior art keywords
biocompatible polymer
particles
active principle
support phase
stirring
Prior art date
Application number
CH01436/94A
Other languages
English (en)
French (fr)
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of CH688572A5 publication Critical patent/CH688572A5/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
CH01436/94A 1993-05-15 1994-05-09 Procédé pour la préparation à sec de particules, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telle particules. CH688572A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (1)

Publication Number Publication Date
CH688572A5 true CH688572A5 (fr) 1997-11-28

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
CH01436/94A CH688572A5 (fr) 1993-05-15 1994-05-09 Procédé pour la préparation à sec de particules, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telle particules.

Country Status (35)

Country Link
JP (1) JP3139913B2 (de)
KR (1) KR100341261B1 (de)
CN (1) CN1050534C (de)
AT (1) AT406017B (de)
AU (1) AU685094B2 (de)
BE (1) BE1008323A3 (de)
BR (1) BR9401968A (de)
CA (1) CA2123481C (de)
CH (1) CH688572A5 (de)
DE (1) DE4416812C2 (de)
DK (1) DK171454B1 (de)
DZ (1) DZ1779A1 (de)
ES (1) ES2097083B1 (de)
FI (1) FI112915B (de)
FR (1) FR2705232B1 (de)
GB (2) GB9310030D0 (de)
GR (1) GR1002034B (de)
HK (1) HK1002831A1 (de)
HU (1) HU220617B1 (de)
IE (1) IE940392A1 (de)
IN (1) IN182330B (de)
IT (1) IT1269508B (de)
LU (1) LU88482A1 (de)
MA (1) MA23194A1 (de)
NL (1) NL9400795A (de)
NO (1) NO307403B1 (de)
NZ (1) NZ260520A (de)
OA (1) OA09939A (de)
PL (1) PL175780B1 (de)
PT (1) PT101518B (de)
RU (1) RU2125869C1 (de)
SE (1) SE519004C2 (de)
SG (1) SG46631A1 (de)
TN (1) TNSN94046A1 (de)
ZA (1) ZA943316B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69435055T2 (de) * 1993-01-06 2008-12-04 IPSEN Manufacturing Ireland Ltd., Blanchardstown Bioabbaubare Polyester zur Herstellung ionischer molekularer Konjugate mit bioaktiven Polypeptiden
WO1994015587A2 (en) * 1993-01-06 1994-07-21 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
WO2001036000A1 (en) 1999-11-15 2001-05-25 Bio Syntech Canada, Inc. Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
MY133977A (en) * 2000-06-16 2007-11-30 Nippon Catalytic Chem Ind Crosslinked polymers containing tertiary amine and/or quaternary ammonium salt structures, processes for making and uses thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (de) * 1987-10-14 1990-01-15 Debiopharm Sa
AU2810189A (en) * 1987-10-30 1989-05-23 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
JP3191948B2 (ja) * 1990-04-12 2001-07-23 塩野義製薬株式会社 被覆製剤およびその製造法
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE467815B (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
JPH07507768A (ja) * 1992-03-12 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド Ａｃｔｈ含有マイクロスフェアの制御放出
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
ATE222500T1 (de) * 1992-06-11 2002-09-15 Alkermes Inc Enythropoietin enthaltendes arzneimittelabgabesystem
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
IE940392A1 (en) 1994-11-16
GB9409565D0 (en) 1994-07-06
SE519004C2 (sv) 2002-12-17
PT101518B (pt) 2000-12-29
TNSN94046A1 (fr) 1995-04-25
AU6308494A (en) 1994-11-17
GB2277915B (en) 1997-10-29
ITMI940931A0 (it) 1994-05-11
NZ260520A (en) 1994-12-22
BR9401968A (pt) 1994-12-13
IT1269508B (it) 1997-04-01
CA2123481A1 (en) 1994-11-16
GR1002034B (en) 1995-10-31
ES2097083B1 (es) 1997-12-01
ATA98794A (de) 1999-06-15
LU88482A1 (fr) 1994-12-01
RU2125869C1 (ru) 1999-02-10
ITMI940931A1 (it) 1995-11-11
GB9310030D0 (en) 1993-06-30
JP3139913B2 (ja) 2001-03-05
SE9401557L (sv) 1994-11-16
DK171454B1 (da) 1996-11-04
ES2097083A1 (es) 1997-03-16
KR100341261B1 (ko) 2002-09-27
AU685094B2 (en) 1998-01-15
NO307403B1 (no) 2000-04-03
FR2705232B1 (fr) 1995-08-25
BE1008323A3 (fr) 1996-04-02
CN1050534C (zh) 2000-03-22
FI942222A0 (fi) 1994-05-13
ZA943316B (en) 1995-01-16
FI112915B (fi) 2004-02-13
IN182330B (de) 1999-03-20
FI942222A (fi) 1994-11-16
PT101518A (pt) 1995-03-01
NO941810D0 (no) 1994-05-13
DE4416812A1 (de) 1994-11-17
GB2277915A (en) 1994-11-16
HU9401412D0 (en) 1994-08-29
HUT67599A (en) 1995-04-28
OA09939A (fr) 1994-11-15
DZ1779A1 (fr) 2002-02-17
SE9401557D0 (sv) 1994-05-05
NL9400795A (nl) 1994-12-01
HU220617B1 (hu) 2002-03-28
SG46631A1 (en) 1998-02-20
JPH072652A (ja) 1995-01-06
NO941810L (no) 1994-11-16
PL175780B1 (pl) 1999-02-26
DE4416812C2 (de) 2003-02-06
AT406017B (de) 2000-01-25
CA2123481C (en) 2005-01-11
DK54994A (da) 1994-11-16
MA23194A1 (fr) 1994-12-31
FR2705232A1 (fr) 1994-11-25
HK1002831A1 (en) 1998-09-18
CN1104557A (zh) 1995-07-05

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