CH673947A5 - - Google Patents
Download PDFInfo
- Publication number
- CH673947A5 CH673947A5 CH3616/87A CH361687A CH673947A5 CH 673947 A5 CH673947 A5 CH 673947A5 CH 3616/87 A CH3616/87 A CH 3616/87A CH 361687 A CH361687 A CH 361687A CH 673947 A5 CH673947 A5 CH 673947A5
- Authority
- CH
- Switzerland
- Prior art keywords
- temazepam
- milligrams
- capsule
- use according
- insomnia
- Prior art date
Links
- SEQDDYPDSLOBDC-UHFFFAOYSA-N Temazepam Chemical compound N=1C(O)C(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 SEQDDYPDSLOBDC-UHFFFAOYSA-N 0.000 claims description 47
- 229960003188 temazepam Drugs 0.000 claims description 47
- 239000007903 gelatin capsule Substances 0.000 claims description 22
- 239000002775 capsule Substances 0.000 claims description 17
- 239000002245 particle Substances 0.000 claims description 15
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims description 11
- 206010022437 insomnia Diseases 0.000 claims description 11
- 239000003937 drug carrier Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 230000004622 sleep time Effects 0.000 description 11
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229940068196 placebo Drugs 0.000 description 4
- 239000000902 placebo Substances 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 230000001052 transient effect Effects 0.000 description 2
- 238000004438 BET method Methods 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 229910052743 krypton Inorganic materials 0.000 description 1
- DNNSSWSSYDEUBZ-UHFFFAOYSA-N krypton atom Chemical compound [Kr] DNNSSWSSYDEUBZ-UHFFFAOYSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004441 surface measurement Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91057186A | 1986-09-23 | 1986-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH673947A5 true CH673947A5 (fr) | 1990-04-30 |
Family
ID=25429005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH3616/87A CH673947A5 (fr) | 1986-09-23 | 1987-09-18 |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS63101325A (fr) |
| BE (1) | BE1000318A4 (fr) |
| CA (1) | CA1302886C (fr) |
| CH (1) | CH673947A5 (fr) |
| DE (1) | DE3731840A1 (fr) |
| FR (1) | FR2604091B1 (fr) |
| GB (1) | GB2195242A (fr) |
| IT (1) | IT1221509B (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19603402A1 (de) * | 1995-02-24 | 1996-08-29 | Basf Ag | Weichgelatinekapseln |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL60806A0 (en) * | 1979-09-14 | 1980-10-26 | Sparamedica Ag | Pharmaceutical compositions containing a benzodiazepine derivatives and a neuroleptic |
| DE3033919A1 (de) * | 1980-09-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
| DE3307353C2 (de) * | 1983-03-02 | 1985-01-31 | R.P. Scherer GmbH, 6930 Eberbach | Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung |
| GB8305693D0 (en) * | 1983-03-02 | 1983-04-07 | Scherer Ltd R P | Pharmaceutical compositions |
| EP0232254A1 (fr) * | 1985-07-24 | 1987-08-19 | SETH, Pyare | Composition pharmaceutique contenant de l'oxazepam |
-
1987
- 1987-09-18 CH CH3616/87A patent/CH673947A5/de not_active IP Right Cessation
- 1987-09-21 FR FR878713108A patent/FR2604091B1/fr not_active Expired
- 1987-09-21 BE BE8701058A patent/BE1000318A4/fr not_active IP Right Cessation
- 1987-09-21 GB GB08722205A patent/GB2195242A/en not_active Withdrawn
- 1987-09-22 IT IT48408/87A patent/IT1221509B/it active
- 1987-09-22 DE DE19873731840 patent/DE3731840A1/de not_active Withdrawn
- 1987-09-22 JP JP62236428A patent/JPS63101325A/ja active Pending
- 1987-09-22 CA CA000547518A patent/CA1302886C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63101325A (ja) | 1988-05-06 |
| IT1221509B (it) | 1990-07-06 |
| GB2195242A (en) | 1988-04-07 |
| IT8748408A0 (it) | 1987-09-22 |
| FR2604091B1 (fr) | 1989-05-05 |
| CA1302886C (fr) | 1992-06-09 |
| BE1000318A4 (fr) | 1988-10-18 |
| GB8722205D0 (en) | 1987-10-28 |
| FR2604091A1 (fr) | 1988-03-25 |
| DE3731840A1 (de) | 1988-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |