CH669523A5 - - Google Patents

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Publication number
CH669523A5
CH669523A5 CH2553/86A CH255386A CH669523A5 CH 669523 A5 CH669523 A5 CH 669523A5 CH 2553/86 A CH2553/86 A CH 2553/86A CH 255386 A CH255386 A CH 255386A CH 669523 A5 CH669523 A5 CH 669523A5
Authority
CH
Switzerland
Prior art keywords
mixture
ibuprofen
coated
tablets
cellulose
Prior art date
Application number
CH2553/86A
Other languages
German (de)
English (en)
Inventor
Pyare Lal Seth
Original Assignee
Mepha Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mepha Ag filed Critical Mepha Ag
Priority to CH2553/86A priority Critical patent/CH669523A5/de
Priority to EP86117458A priority patent/EP0250648B1/de
Priority to ES198686117458T priority patent/ES2029228T3/es
Priority to AT86117458T priority patent/ATE66370T1/de
Priority to DE8686117458T priority patent/DE3681031D1/de
Priority to IL81045A priority patent/IL81045A/xx
Priority to NO865195A priority patent/NO173081C/no
Priority to NZ218734A priority patent/NZ218734A/xx
Priority to FI865227A priority patent/FI88580C/fi
Priority to JP61303589A priority patent/JPS635020A/ja
Priority to ZA869586A priority patent/ZA869586B/xx
Priority to CN86108644A priority patent/CN1023191C/zh
Priority to KR1019860010971A priority patent/KR930008956B1/ko
Priority to US06/944,552 priority patent/US4867987A/en
Priority to AU66807/86A priority patent/AU590370B2/en
Priority to CA000525825A priority patent/CA1276560C/en
Priority to DK616186A priority patent/DK616186A/da
Publication of CH669523A5 publication Critical patent/CH669523A5/de
Priority to GR91401076T priority patent/GR3002579T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Control Of El Displays (AREA)
  • Manufacturing Of Tubular Articles Or Embedded Moulded Articles (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
CH2553/86A 1986-06-25 1986-06-25 CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CH2553/86A CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-06-25 1986-06-25
EP86117458A EP0250648B1 (de) 1986-06-25 1986-12-16 Pharmazeutisches Präparat zur verzögerten Freigabe von Ibuprofen
ES198686117458T ES2029228T3 (es) 1986-06-25 1986-12-16 Procedimiento para la produccion de un preparado retardado de ibuprofeno.
AT86117458T ATE66370T1 (de) 1986-06-25 1986-12-16 Pharmazeutisches praeparat zur verzoegerten freigabe von ibuprofen.
DE8686117458T DE3681031D1 (de) 1986-06-25 1986-12-16 Pharmazeutisches praeparat zur verzoegerten freigabe von ibuprofen.
JP61303589A JPS635020A (ja) 1986-06-25 1986-12-19 制御放出性イブプロフエン製剤
KR1019860010971A KR930008956B1 (ko) 1986-06-25 1986-12-19 서방형 이부프로펜 제제의 제조방법
NZ218734A NZ218734A (en) 1986-06-25 1986-12-19 Tablets containing coated microspheres which contain ibuprofen (2-(4-isobutyl phenyl)propanoic acid)
FI865227A FI88580C (fi) 1986-06-25 1986-12-19 Foerfarande foer framstaellning av ett depotpreparat av ibuprofen
IL81045A IL81045A (en) 1986-06-25 1986-12-19 Pharmaceutical product for the sustained release of ibuprofen and its preparation
ZA869586A ZA869586B (en) 1986-06-25 1986-12-19 Pharmaceutical product for the sustained release of ibuprofen
CN86108644A CN1023191C (zh) 1986-06-25 1986-12-19 生产持续释放异丁丙苯酸制剂的方法
NO865195A NO173081C (no) 1986-06-25 1986-12-19 Fremgangsmaate for fremstilling av et retard-preparat av ibuprofen
US06/944,552 US4867987A (en) 1986-06-25 1986-12-19 Pharmaceutical product for the sustained release of ibuprofen
AU66807/86A AU590370B2 (en) 1986-06-25 1986-12-19 Improvements in or relating to pharmaceutical products
CA000525825A CA1276560C (en) 1986-06-25 1986-12-19 Process for producing a sustained release ibuprofen preparation
DK616186A DK616186A (da) 1986-06-25 1986-12-19 Farmaceutisk praeparat med retarderet frigivelse af ibuprofen
GR91401076T GR3002579T3 (en) 1986-06-25 1991-08-22 Pharmaceutical preparation for the sustained release of ibuprofen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2553/86A CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-06-25 1986-06-25

Publications (1)

Publication Number Publication Date
CH669523A5 true CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-03-31

Family

ID=4236387

Family Applications (1)

Application Number Title Priority Date Filing Date
CH2553/86A CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-06-25 1986-06-25

Country Status (18)

Country Link
US (1) US4867987A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0250648B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS635020A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR930008956B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1023191C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE66370T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU590370B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1276560C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH669523A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3681031D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK616186A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2029228T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI88580C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3002579T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL81045A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO173081C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ218734A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA869586B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
US4970081A (en) * 1989-01-03 1990-11-13 Sterling Drug Inc. Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith
US5213807A (en) * 1990-05-03 1993-05-25 Chemburkar Pramod B Pharmaceutical composition containing ibuprofen and a prostaglandin
JPH04230625A (ja) * 1990-12-27 1992-08-19 Standard Chem & Pharmaceut Corp Ltd 噴霧乾燥したジクロフェナクナトリウムを含み腸溶性の被覆を有するマイクロカプセルからなる微分散した錠剤組成物の製造方法
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
US5637625A (en) * 1996-03-19 1997-06-10 Research Triangle Pharmaceuticals Ltd. Propofol microdroplet formulations
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
EP1338275B1 (en) * 2000-11-28 2012-02-29 Nartsissov, Yaroslav Pharmaceutical composition, the use thereof and method for producing said composition
SI1551372T1 (en) * 2002-09-20 2018-08-31 Alpharma Pharmaceuticals Llc SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES
AU2006211047B2 (en) * 2005-02-04 2011-03-24 Philip Morris Products S.A. Cigarette and filter with cellulosic flavor addition
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
BRPI0619868A8 (pt) * 2005-12-16 2016-06-07 Hanmi Pharm Ind Co Ltd Dispersão sólida compreendendo um ingrediente ativo tendo um ponto de fusão baixo e comprimido para administração oral compreendendo o mesmo
DK2484346T3 (en) 2006-06-19 2017-04-24 Alpharma Pharmaceuticals Llc Pharmaceutical compositions
US20080233156A1 (en) * 2006-10-11 2008-09-25 Alpharma, Inc. Pharmaceutical compositions
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US20090196890A1 (en) * 2007-12-17 2009-08-06 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
JP5953646B2 (ja) * 2009-11-24 2016-07-20 大正製薬株式会社 イブプロフェン含有固形製剤
CA2792523C (en) * 2010-03-09 2018-01-09 Alkermes Pharma Ireland Limited Alcohol resistant enteric pharmaceutical compositions
CA3018328A1 (en) 2014-10-31 2016-04-30 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1228757B (de) * 1962-06-28 1966-11-17 Haessle Ab Verfahren zur Herstellung eines in Wasser und Magensaft rasch zerfallenden UEberzuges auf festen Arzneiformen
JPS51127041A (en) * 1975-04-23 1976-11-05 Toyama Chem Co Ltd A process for preparing novel 2-( substituted phenyl) alkane acids and their salts.
US4447454A (en) * 1977-04-01 1984-05-08 The Upjohn Company Analgetic compounds, compositions and process of treatment
CA1125698A (en) * 1978-03-09 1982-06-15 Masaru Yoshida Process for preparing a polymer composition
JPS6028809B2 (ja) * 1979-08-21 1985-07-06 日本原子力研究所 イブプロフエン徐放剤組成物の製造方法
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
US4713249A (en) * 1981-11-12 1987-12-15 Schroeder Ulf Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
DE3205504C2 (de) * 1982-02-16 1983-12-01 Dolorgiet Gmbh & Co Kg, 5300 Bonn Äußerlich anwendbares, Ibuprofen enthaltendes Arzneimittel
US4587249A (en) * 1982-07-22 1986-05-06 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
IE55367B1 (en) * 1982-07-22 1990-08-29 Richardson Vicks Inc Improved analgesic and anti-inflammatory compositions comprising caffeine
US4486436A (en) * 1982-07-22 1984-12-04 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB2132887A (en) * 1982-11-15 1984-07-18 Procter & Gamble Enteric-coated anti-inflammatory compositions
JPS59122425A (ja) * 1982-12-27 1984-07-14 Kaken Pharmaceut Co Ltd 持続性製剤およびその製造法
US4567183A (en) * 1983-03-11 1986-01-28 Analgesic Associates Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4522826A (en) * 1984-02-08 1985-06-11 Richardson-Vicks Inc. Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same
US4585783A (en) * 1984-02-08 1986-04-29 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances

Also Published As

Publication number Publication date
DK616186A (da) 1987-12-26
EP0250648A2 (de) 1988-01-07
GR3002579T3 (en) 1993-01-25
KR880000090A (ko) 1988-03-23
ATE66370T1 (de) 1991-09-15
FI88580C (fi) 1993-06-10
KR930008956B1 (ko) 1993-09-17
NO865195D0 (no) 1986-12-19
DK616186D0 (da) 1986-12-19
CN86108644A (zh) 1988-01-06
IL81045A0 (en) 1987-03-31
JPS635020A (ja) 1988-01-11
IL81045A (en) 1990-11-05
ZA869586B (en) 1988-07-27
AU6680786A (en) 1988-01-07
CN1023191C (zh) 1993-12-22
CA1276560C (en) 1990-11-20
US4867987A (en) 1989-09-19
NO173081C (no) 1993-10-27
ES2029228T3 (es) 1992-08-01
EP0250648B1 (de) 1991-08-21
DE3681031D1 (de) 1991-09-26
FI865227A7 (fi) 1987-12-26
NZ218734A (en) 1990-03-27
EP0250648A3 (en) 1988-03-23
AU590370B2 (en) 1989-11-02
FI865227A0 (fi) 1986-12-19
FI88580B (fi) 1993-02-26
NO865195L (no) 1987-12-28
NO173081B (no) 1993-07-19

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Legal Events

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PL Patent ceased