CH668593A5 - Composes heterocycliques appartenant aux series indoliques et leur preparation. - Google Patents

Composes heterocycliques appartenant aux series indoliques et leur preparation. Download PDF

Info

Publication number
CH668593A5
CH668593A5 CH4390/86A CH439086A CH668593A5 CH 668593 A5 CH668593 A5 CH 668593A5 CH 4390/86 A CH4390/86 A CH 4390/86A CH 439086 A CH439086 A CH 439086A CH 668593 A5 CH668593 A5 CH 668593A5
Authority
CH
Switzerland
Prior art keywords
hydrogen
formula
radical
lower alkyl
substituent
Prior art date
Application number
CH4390/86A
Other languages
English (en)
French (fr)
Inventor
William E Kreigbaum
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH668593A5 publication Critical patent/CH668593A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CH4390/86A 1982-09-03 1983-09-05 Composes heterocycliques appartenant aux series indoliques et leur preparation. CH668593A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41474882A 1982-09-03 1982-09-03

Publications (1)

Publication Number Publication Date
CH668593A5 true CH668593A5 (fr) 1989-01-13

Family

ID=23642783

Family Applications (2)

Application Number Title Priority Date Filing Date
CH4855/83A CH661512A5 (fr) 1982-09-03 1983-09-05 1-pyridyloxy-3-indolylalkylamino-propanols substitues et leur preparation.
CH4390/86A CH668593A5 (fr) 1982-09-03 1983-09-05 Composes heterocycliques appartenant aux series indoliques et leur preparation.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH4855/83A CH661512A5 (fr) 1982-09-03 1983-09-05 1-pyridyloxy-3-indolylalkylamino-propanols substitues et leur preparation.

Country Status (28)

Country Link
JP (1) JPS5965087A (hu)
KR (1) KR870001019B1 (hu)
AT (1) AT387385B (hu)
AU (4) AU567112B2 (hu)
BE (1) BE897671A (hu)
CA (1) CA1236834A (hu)
CH (2) CH661512A5 (hu)
CY (1) CY1521A (hu)
DE (1) DE3331612A1 (hu)
DK (1) DK399783A (hu)
ES (4) ES525243A0 (hu)
FI (1) FI79709C (hu)
FR (1) FR2543952B1 (hu)
GB (1) GB2126230B (hu)
GR (1) GR79061B (hu)
HK (1) HK17490A (hu)
HU (2) HU194164B (hu)
IE (1) IE56201B1 (hu)
IL (1) IL69618A (hu)
IT (1) IT1169459B (hu)
LU (1) LU84986A1 (hu)
NL (1) NL8303038A (hu)
NO (1) NO161258C (hu)
NZ (1) NZ205466A (hu)
PT (1) PT77282B (hu)
SE (2) SE460419B (hu)
YU (2) YU45150B (hu)
ZA (1) ZA836469B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543952B1 (fr) * 1982-09-03 1986-02-21 Bristol Myers Co Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5030640A (en) * 1989-01-05 1991-07-09 Merck & Co., Inc. Novel β-adrenergic agonists and pharmaceutical compositions thereof
WO2002038106A2 (en) * 2000-10-25 2002-05-16 Smithkline Beecham Corporation Calcilytic compounds
KR100457857B1 (ko) * 2002-05-23 2004-11-18 (주) 비엔씨바이오팜 2-[2-(3-인돌릴)에틸아미노]피리딘 유도체, 그 제조방법및 이를 포함하는 항바이러스용 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
FR2543952B1 (fr) * 1982-09-03 1986-02-21 Bristol Myers Co Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
CA1241660A (en) * 1984-06-25 1988-09-06 Yvan Guindon Indole-2-alkanoic acids

Also Published As

Publication number Publication date
IE832063L (en) 1984-03-03
DE3331612A1 (de) 1984-03-08
AU8055887A (en) 1988-02-18
SE8802265D0 (sv) 1988-06-16
YU180383A (en) 1988-06-30
FI833102A0 (fi) 1983-08-31
FI833102A (fi) 1984-03-04
IE56201B1 (en) 1991-05-22
IL69618A (en) 1987-02-27
ES8604931A1 (es) 1986-02-16
IL69618A0 (en) 1983-12-30
CA1236834A (en) 1988-05-17
IT8322765A0 (it) 1983-09-02
NO833128L (no) 1984-03-05
KR840006235A (ko) 1984-11-22
FI79709C (fi) 1990-02-12
BE897671A (fr) 1984-03-02
HU194164B (en) 1988-01-28
AU613589B2 (en) 1991-08-08
HU192862B (en) 1987-07-28
ES547111A0 (es) 1986-02-16
SE8802265L (sv) 1988-06-16
PT77282B (en) 1986-04-28
AU609068B2 (en) 1991-04-26
JPS5965087A (ja) 1984-04-13
GB2126230A (en) 1984-03-21
NL8303038A (nl) 1984-04-02
YU45150B (en) 1992-03-10
NZ205466A (en) 1986-12-05
DK399783A (da) 1984-03-04
AU8055787A (en) 1988-02-18
YU224786A (en) 1987-10-31
SE8304751D0 (sv) 1983-09-02
LU84986A1 (fr) 1984-04-24
ATA315583A (de) 1988-06-15
ES8604930A1 (es) 1986-02-16
SE460419B (sv) 1989-10-09
CY1521A (en) 1990-11-16
GB2126230B (en) 1987-01-14
AU567112B2 (en) 1987-11-12
YU44940B (en) 1991-04-30
IT1169459B (it) 1987-05-27
ES531872A0 (es) 1985-05-16
FR2543952A1 (fr) 1984-10-12
ES547110A0 (es) 1986-02-16
FR2543952B1 (fr) 1986-02-21
ES8507537A1 (es) 1985-09-01
FI79709B (fi) 1989-10-31
ES525243A0 (es) 1985-09-01
HK17490A (en) 1990-03-16
ES8505200A1 (es) 1985-05-16
NO161258B (no) 1989-04-17
AU8055987A (en) 1988-02-18
CH661512A5 (fr) 1987-07-31
NO161258C (no) 1989-07-26
SE8304751L (sv) 1984-03-04
KR870001019B1 (ko) 1987-05-23
GR79061B (hu) 1984-10-02
AU1859283A (en) 1984-03-08
AT387385B (de) 1989-01-10
AU609067B2 (en) 1991-04-26
PT77282A (en) 1983-10-01
GB8323641D0 (en) 1983-10-05
ZA836469B (en) 1984-04-25
DK399783D0 (da) 1983-09-01

Similar Documents

Publication Publication Date Title
CH646969A5 (fr) Derives du beta-amino-3 nor-tropane.
EP0011059B1 (fr) Procédé de préparation de la (+,-) vincadifformine et d'autres dérivés pentacycliques apparentés
EP0406112B1 (fr) 1-Benzhydrylazétidines, leur préparation et leur application comme intermédiaires pour la préparation de composés à activité antimicrobienne
CH668593A5 (fr) Composes heterocycliques appartenant aux series indoliques et leur preparation.
EP0086678B1 (fr) Procédé pour la préparation d'acyl-2 hexahydro-1,3,4,6,7,11b-2H-pyrazino (2,1-a)isoquinoléinones-4 et intermédiaires
EP0155870B1 (fr) 3-aminoazétidine, ses sels, procédé pour leur préparation et intermédiaires de synthèse
FR2523977A1 (fr) Procede et composes intermediaires cles pour la preparation de la 19-norandrostenedione
BE900835R (fr) Derives de phenethanol-amine.
EP0251938B1 (fr) Procédé de synthèse stéréospécifique de dérivés de l'indole
FR2628738A1 (fr) Produits chimiques intermediaires utilisables pour la preparation de certains agents anti-histaminiques h2
BE793180A (fr) Composes utiles en fluorometrie
EP0005654A1 (fr) Procédé d'isomérisation des dérivés de la vinyl-3 pipéridine
CH624089A5 (hu)
FR2727410A1 (fr) Chlorures de sulfonyles, leur preparation et leur utilisation comme intermediaires de synthese
WO1998031671A1 (fr) Derives de pyridone, leur preparation et leur utilisation comme intermediaires de synthese
CH671762A5 (hu)
BE889338A (fr) Nouveau procede de preparation d'indolo (2',3';3,4) pyrido (1,2-b) quinazolines-5-ones
FR2555582A1 (fr) Procede de preparation de 4-(2-phenoxyethyl)-1,2,4-triazolone
CH645627A5 (fr) Carbanion de la papaverine et sa preparation.
FR2615853A1 (fr) Nouveau procede pour la preparation de derives de la piperazine pharmacologiquement actifs, derives et nouveaux intermediaires obtenus
FR2485538A1 (fr) Nouveau procede de preparation d'indolo(2',3';3,4)-pyrido(1,2-b)quinazoline-5-ones
EP0199618A1 (fr) Nouvelles 5-H pyrido (3',4':4,5) pyrrolo (3,2-c) pyridones, leur procédé de préparation et leur application en tant qu'intermédiaires de synthèse
WO1999050207A1 (fr) Procede pour la preparation du 2-chloro-1-cyclohexyl-4-ethylnylbenzene
FR2461702A1 (fr) Nouveaux derives de l'isoquinoleine et leur procede de preparation
BE566396A (hu)

Legal Events

Date Code Title Description
PL Patent ceased