ES8604930A1 - Un procedimiento de preparacion de nuevos derivados de 2- propanol - Google Patents
Un procedimiento de preparacion de nuevos derivados de 2- propanolInfo
- Publication number
- ES8604930A1 ES8604930A1 ES547110A ES547110A ES8604930A1 ES 8604930 A1 ES8604930 A1 ES 8604930A1 ES 547110 A ES547110 A ES 547110A ES 547110 A ES547110 A ES 547110A ES 8604930 A1 ES8604930 A1 ES 8604930A1
- Authority
- ES
- Spain
- Prior art keywords
- propanols
- coupling
- pyridinyloxy
- substituted
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS DE 2-PROPANOL. CONSISTE EN COPULAR UNA PIRIDINA Z-SUSTITUIDA DE FORMULA (II) CON UN PROPANOL W-SUSTITUIDO O INTERMEDIO DE PROPANOL INCIPIENTE DE FORMULA (III), PARA OBTENER DERIVADOS DE 2-PROPANOL DE FORMULA (I) Y SUS SALES DE ADICION DE CAIDOS, DONDE X ESTA SELECCIONADO ENTRE EL GRUPO FORMADO POR -CHO, -CN, -CF3, -CONRARB O -CO2RC, DONDE RA Y RB SON H O RC, Y RC PUEDE SER ALQUILO INFERIOR DE C 1 A 4, ARILO O ARIL-ALQUILO INFERIOR; Y ES UN SEGUNDO SUSTITUYENTE EN EL ANILLO DE PIRIDINA Y ES H, HALOGENO, ALCOXI INFERIOR C 1 A 4 Y OTROS; R ES H Y OTROS; R1, R2, A Y B ESTAN SELECCIONADOS INDEPENDIENTEMENTE ENTRE H Y ALQUILO INFERIOR; C ES UN SUSTITUYENTE EN EL ANILLO BENCENICO DEL INDOL Y ES H, HALOGENO Y OTROS; Y EL SISTEMA INDOLILO ESTA UNIDO POR SU POSICION 2 O 3.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41474882A | 1982-09-03 | 1982-09-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604930A1 true ES8604930A1 (es) | 1986-02-16 |
| ES547110A0 ES547110A0 (es) | 1986-02-16 |
Family
ID=23642783
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525243A Granted ES525243A0 (es) | 1982-09-03 | 1983-08-30 | Un procedimiento de preparacion de nuevos derivados de 2-propanol. |
| ES531872A Granted ES531872A0 (es) | 1982-09-03 | 1984-04-25 | Un procedimiento para la preparacion de nuevos derivados de 2-propanol |
| ES547111A Expired ES8604931A1 (es) | 1982-09-03 | 1985-09-19 | Un procedimiento de preparacion de nuevos derivados de 2- propanol |
| ES547110A Expired ES8604930A1 (es) | 1982-09-03 | 1985-09-19 | Un procedimiento de preparacion de nuevos derivados de 2- propanol |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525243A Granted ES525243A0 (es) | 1982-09-03 | 1983-08-30 | Un procedimiento de preparacion de nuevos derivados de 2-propanol. |
| ES531872A Granted ES531872A0 (es) | 1982-09-03 | 1984-04-25 | Un procedimiento para la preparacion de nuevos derivados de 2-propanol |
| ES547111A Expired ES8604931A1 (es) | 1982-09-03 | 1985-09-19 | Un procedimiento de preparacion de nuevos derivados de 2- propanol |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS5965087A (es) |
| KR (1) | KR870001019B1 (es) |
| AT (1) | AT387385B (es) |
| AU (4) | AU567112B2 (es) |
| BE (1) | BE897671A (es) |
| CA (1) | CA1236834A (es) |
| CH (2) | CH661512A5 (es) |
| CY (1) | CY1521A (es) |
| DE (1) | DE3331612A1 (es) |
| DK (1) | DK399783A (es) |
| ES (4) | ES525243A0 (es) |
| FI (1) | FI79709C (es) |
| FR (1) | FR2543952B1 (es) |
| GB (1) | GB2126230B (es) |
| GR (1) | GR79061B (es) |
| HK (1) | HK17490A (es) |
| HU (2) | HU194164B (es) |
| IE (1) | IE56201B1 (es) |
| IL (1) | IL69618A (es) |
| IT (1) | IT1169459B (es) |
| LU (1) | LU84986A1 (es) |
| NL (1) | NL8303038A (es) |
| NO (1) | NO161258C (es) |
| NZ (1) | NZ205466A (es) |
| PT (1) | PT77282B (es) |
| SE (2) | SE460419B (es) |
| YU (2) | YU45150B (es) |
| ZA (1) | ZA836469B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2543952B1 (fr) * | 1982-09-03 | 1986-02-21 | Bristol Myers Co | Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique |
| DE3721260A1 (de) * | 1987-06-27 | 1989-01-12 | Beiersdorf Ag | Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
| US5030640A (en) * | 1989-01-05 | 1991-07-09 | Merck & Co., Inc. | Novel β-adrenergic agonists and pharmaceutical compositions thereof |
| US20040009980A1 (en) * | 2000-10-25 | 2004-01-15 | Pradip Bhatnagar | Calcilytic compounds |
| KR100457857B1 (ko) * | 2002-05-23 | 2004-11-18 | (주) 비엔씨바이오팜 | 2-[2-(3-인돌릴)에틸아미노]피리딘 유도체, 그 제조방법및 이를 포함하는 항바이러스용 약학적 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4144343A (en) * | 1978-01-04 | 1979-03-13 | Merck & Co., Inc. | Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines |
| FR2463765A1 (fr) * | 1979-08-17 | 1981-02-27 | Clin Midy | Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire |
| FR2543952B1 (fr) * | 1982-09-03 | 1986-02-21 | Bristol Myers Co | Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique |
| CA1241660A (en) * | 1984-06-25 | 1988-09-06 | Yvan Guindon | Indole-2-alkanoic acids |
-
1983
- 1983-08-26 FR FR8313793A patent/FR2543952B1/fr not_active Expired
- 1983-08-30 ES ES525243A patent/ES525243A0/es active Granted
- 1983-08-30 GR GR72336A patent/GR79061B/el unknown
- 1983-08-31 FI FI833102A patent/FI79709C/fi not_active IP Right Cessation
- 1983-08-31 AU AU18592/83A patent/AU567112B2/en not_active Ceased
- 1983-08-31 NL NL8303038A patent/NL8303038A/nl not_active Application Discontinuation
- 1983-08-31 ZA ZA836469A patent/ZA836469B/xx unknown
- 1983-09-01 NO NO833128A patent/NO161258C/no unknown
- 1983-09-01 IL IL69618A patent/IL69618A/xx unknown
- 1983-09-01 DE DE19833331612 patent/DE3331612A1/de not_active Withdrawn
- 1983-09-01 CA CA000435880A patent/CA1236834A/en not_active Expired
- 1983-09-01 PT PT77282A patent/PT77282B/pt not_active IP Right Cessation
- 1983-09-01 DK DK399783A patent/DK399783A/da not_active Application Discontinuation
- 1983-09-02 LU LU84986A patent/LU84986A1/fr unknown
- 1983-09-02 BE BE211466A patent/BE897671A/fr unknown
- 1983-09-02 AT AT0315583A patent/AT387385B/de not_active IP Right Cessation
- 1983-09-02 SE SE8304751A patent/SE460419B/sv not_active IP Right Cessation
- 1983-09-02 HU HU864311A patent/HU194164B/hu not_active IP Right Cessation
- 1983-09-02 NZ NZ205466A patent/NZ205466A/en unknown
- 1983-09-02 KR KR1019830004140A patent/KR870001019B1/ko not_active IP Right Cessation
- 1983-09-02 IE IE2063/83A patent/IE56201B1/en unknown
- 1983-09-02 GB GB08323641A patent/GB2126230B/en not_active Expired
- 1983-09-02 JP JP58160596A patent/JPS5965087A/ja active Pending
- 1983-09-02 IT IT22765/83A patent/IT1169459B/it active
- 1983-09-02 HU HU833064A patent/HU192862B/hu not_active IP Right Cessation
- 1983-09-05 CH CH4855/83A patent/CH661512A5/fr not_active IP Right Cessation
- 1983-09-05 CH CH4390/86A patent/CH668593A5/fr not_active IP Right Cessation
- 1983-09-05 YU YU1803/83A patent/YU45150B/xx unknown
-
1984
- 1984-04-25 ES ES531872A patent/ES531872A0/es active Granted
-
1985
- 1985-09-19 ES ES547111A patent/ES8604931A1/es not_active Expired
- 1985-09-19 ES ES547110A patent/ES8604930A1/es not_active Expired
-
1986
- 1986-12-25 YU YU2247/86A patent/YU44940B/xx unknown
-
1987
- 1987-10-30 AU AU80559/87A patent/AU613589B2/en not_active Ceased
- 1987-10-30 AU AU80558/87A patent/AU609068B2/en not_active Ceased
- 1987-10-30 AU AU80557/87A patent/AU609067B2/en not_active Ceased
-
1988
- 1988-06-16 SE SE8802265A patent/SE8802265D0/xx not_active Application Discontinuation
-
1990
- 1990-03-08 HK HK174/90A patent/HK17490A/xx unknown
- 1990-11-16 CY CY1521A patent/CY1521A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK513481A (da) | Nicotinamidderivater fremgangsmaader til fremstilling heraf midler med indhold heraf og disses anvendelse i landbruget | |
| ES8607934A1 (es) | Procedimiento para preparar nuevos compuestos de 3-piridilo | |
| PT78361B (en) | Preparation process of new furo-(3,4-c)-pyridine derivatives | |
| PT79511B (en) | Preparation process of new 6-vinyl-furo-(3,4-c)-pyridine derivatives | |
| CA1272199C (en) | 2,6-SUBSTITUTE PYRIDINE COMPOUNDS | |
| ZA931537B (en) | 4-Oxo-2-thioxoimidazolidine derivatives. | |
| ES8604930A1 (es) | Un procedimiento de preparacion de nuevos derivados de 2- propanol | |
| DE3060345D1 (en) | Fluortriazine derivatives, process for the preparation of fluortriazin-derivatives and reactive dyes and their application | |
| DE3062601D1 (en) | Pyridine derivatives, processes for preparing them, herbicidal compositions containing them and methods of killing plants therewith | |
| DE3264599D1 (en) | Associates of bases obtained by combining an alkyl or aryllithium and an alkaliamide or hydride, process of polymerisation using them and obtained product | |
| MY102963A (en) | Substituted 1-pyridyloxy-3-indolylalky lamino -2-propanols, preparation, and use thereof | |
| DE3062989D1 (en) | Triazolylphenacyl-pyridyl-ether derivatives, process for their preparation and their application as fungicides | |
| DE3168066D1 (en) | Process for preparing dispersions of polyacrylates, and their use | |
| NZ223437A (en) | 2,6 substituted pyridine derivatives comprising at least two n-containing rings as herbicides | |
| IL62844A (en) | Production of 2,3,5-trichloropyridine | |
| PT71539A (en) | Process for the preparation of 1,2-dihydro-2-oxo-5-(pyridinyl) nicotinonitrile | |
| IE781992L (en) | Packaged food product | |
| ES8603458A1 (es) | Un procedimiento para preparar una 3-r1-4-r2-5-q-6-r-2(1h)-piridinona | |
| IE39467B1 (en) | Mercaptqmethylpyridines and their derivatives | |
| HU178253B (en) | Process for preparing 1,1,2-triphenyl-propane and -propane derivatives | |
| ZA821101B (en) | Novel substituted tetrahydropyrimidinone derivatives,process for their preparation and their use as herbicides | |
| PT74114B (en) | Process for the preparation of 1,2-dihydro-5-(pyridinyl)-nico- tinamide derivatives | |
| GB2052472B (en) | Process for the production of heat-insulating bonded fibrous articles | |
| PT71427A (en) | Process for the preparation of 5-(4-pyridinyl)-2 (1h) pyridinones useful as cardiotonic agents | |
| AU7273881A (en) | Synthesis of 2-(1-(2,5-dimethylphenyl) ethylsulfonyl) pyridine-1-oxide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |