GB2126230B - Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols preparation and use thereof - Google Patents

Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols preparation and use thereof

Info

Publication number
GB2126230B
GB2126230B GB08323641A GB8323641A GB2126230B GB 2126230 B GB2126230 B GB 2126230B GB 08323641 A GB08323641 A GB 08323641A GB 8323641 A GB8323641 A GB 8323641A GB 2126230 B GB2126230 B GB 2126230B
Authority
GB
United Kingdom
Prior art keywords
indolylalkylamino
propanols
pyridyloxy
substituted
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08323641A
Other languages
English (en)
Other versions
GB2126230A (en
GB8323641D0 (en
Inventor
William E Kreighbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB8323641D0 publication Critical patent/GB8323641D0/en
Publication of GB2126230A publication Critical patent/GB2126230A/en
Priority to GB08519637A priority Critical patent/GB2162523B/en
Application granted granted Critical
Publication of GB2126230B publication Critical patent/GB2126230B/en
Priority to MYPI87002781A priority patent/MY102963A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB08323641A 1982-09-03 1983-09-02 Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols preparation and use thereof Expired GB2126230B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB08519637A GB2162523B (en) 1982-09-03 1985-08-05 Intermediates for synthesis of indole derivatives
MYPI87002781A MY102963A (en) 1982-09-03 1987-10-01 Substituted 1-pyridyloxy-3-indolylalky lamino -2-propanols, preparation, and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41474882A 1982-09-03 1982-09-03

Publications (3)

Publication Number Publication Date
GB8323641D0 GB8323641D0 (en) 1983-10-05
GB2126230A GB2126230A (en) 1984-03-21
GB2126230B true GB2126230B (en) 1987-01-14

Family

ID=23642783

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08323641A Expired GB2126230B (en) 1982-09-03 1983-09-02 Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols preparation and use thereof

Country Status (28)

Country Link
JP (1) JPS5965087A (es)
KR (1) KR870001019B1 (es)
AT (1) AT387385B (es)
AU (4) AU567112B2 (es)
BE (1) BE897671A (es)
CA (1) CA1236834A (es)
CH (2) CH668593A5 (es)
CY (1) CY1521A (es)
DE (1) DE3331612A1 (es)
DK (1) DK399783A (es)
ES (4) ES8507537A1 (es)
FI (1) FI79709C (es)
FR (1) FR2543952B1 (es)
GB (1) GB2126230B (es)
GR (1) GR79061B (es)
HK (1) HK17490A (es)
HU (2) HU194164B (es)
IE (1) IE56201B1 (es)
IL (1) IL69618A (es)
IT (1) IT1169459B (es)
LU (1) LU84986A1 (es)
NL (1) NL8303038A (es)
NO (1) NO161258C (es)
NZ (1) NZ205466A (es)
PT (1) PT77282B (es)
SE (2) SE460419B (es)
YU (2) YU45150B (es)
ZA (1) ZA836469B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543952B1 (fr) * 1982-09-03 1986-02-21 Bristol Myers Co Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
DE3721260A1 (de) * 1987-06-27 1989-01-12 Beiersdorf Ag Neue indolylpropanole, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5030640A (en) * 1989-01-05 1991-07-09 Merck & Co., Inc. Novel β-adrenergic agonists and pharmaceutical compositions thereof
PL365643A1 (en) * 2000-10-25 2005-01-10 Smithkline Beecham Corporation Calcilytic compounds
KR100457857B1 (ko) * 2002-05-23 2004-11-18 (주) 비엔씨바이오팜 2-[2-(3-인돌릴)에틸아미노]피리딘 유도체, 그 제조방법및 이를 포함하는 항바이러스용 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
FR2543952B1 (fr) * 1982-09-03 1986-02-21 Bristol Myers Co Composes hydrocarbones heterocycliques appartenant aux series indoliques et leur application pharmacologique
CA1241660A (en) * 1984-06-25 1988-09-06 Yvan Guindon Indole-2-alkanoic acids

Also Published As

Publication number Publication date
ES525243A0 (es) 1985-09-01
IE832063L (en) 1984-03-03
IL69618A0 (en) 1983-12-30
ES547111A0 (es) 1986-02-16
LU84986A1 (fr) 1984-04-24
IE56201B1 (en) 1991-05-22
CY1521A (en) 1990-11-16
YU180383A (en) 1988-06-30
GB2126230A (en) 1984-03-21
AU8055987A (en) 1988-02-18
CH661512A5 (fr) 1987-07-31
BE897671A (fr) 1984-03-02
CH668593A5 (fr) 1989-01-13
ATA315583A (de) 1988-06-15
AU609068B2 (en) 1991-04-26
FI833102A (fi) 1984-03-04
CA1236834A (en) 1988-05-17
FI79709B (fi) 1989-10-31
NL8303038A (nl) 1984-04-02
KR840006235A (ko) 1984-11-22
KR870001019B1 (ko) 1987-05-23
AU1859283A (en) 1984-03-08
AT387385B (de) 1989-01-10
PT77282A (en) 1983-10-01
GB8323641D0 (en) 1983-10-05
HU194164B (en) 1988-01-28
HK17490A (en) 1990-03-16
AU613589B2 (en) 1991-08-08
SE8304751L (sv) 1984-03-04
DE3331612A1 (de) 1984-03-08
JPS5965087A (ja) 1984-04-13
FI833102A0 (fi) 1983-08-31
NO161258C (no) 1989-07-26
YU224786A (en) 1987-10-31
AU8055787A (en) 1988-02-18
IT8322765A0 (it) 1983-09-02
SE8802265D0 (sv) 1988-06-16
AU8055887A (en) 1988-02-18
PT77282B (en) 1986-04-28
ES8604930A1 (es) 1986-02-16
ES8505200A1 (es) 1985-05-16
YU45150B (en) 1992-03-10
IT1169459B (it) 1987-05-27
ES531872A0 (es) 1985-05-16
FR2543952A1 (fr) 1984-10-12
DK399783D0 (da) 1983-09-01
SE8802265L (sv) 1988-06-16
ZA836469B (en) 1984-04-25
ES547110A0 (es) 1986-02-16
SE8304751D0 (sv) 1983-09-02
IL69618A (en) 1987-02-27
FR2543952B1 (fr) 1986-02-21
NZ205466A (en) 1986-12-05
ES8507537A1 (es) 1985-09-01
AU609067B2 (en) 1991-04-26
YU44940B (en) 1991-04-30
DK399783A (da) 1984-03-04
ES8604931A1 (es) 1986-02-16
GR79061B (es) 1984-10-02
NO161258B (no) 1989-04-17
HU192862B (en) 1987-07-28
SE460419B (sv) 1989-10-09
AU567112B2 (en) 1987-11-12
NO833128L (no) 1984-03-05
FI79709C (fi) 1990-02-12

Similar Documents

Publication Publication Date Title
EP0097960A3 (en) Bis-crown-ether derivatives and their use
IL68880A (en) Triazole-ethanol derivatives and their preparation
JPS57118794A (en) Imunosome and preparation thereof
GB2131806B (en) Alkylxylene sulphonate compounds their preparation and use
DE3367385D1 (en) N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use
SG4890G (en) 1-pyrimidinyloxy-3-hetarylalkylamino-2-propanols preparation and uses
IL71658A (en) 17-sulfonylmethylene-steroids and their preparation
DE3367089D1 (en) 3-phenoxy-1-azetidinecarboxamides and their use and preparation
ZA842202B (en) Phenylaminobenzenealkanols and preparation
DE3367607D1 (en) Basic compounds, their preparation and their use
MW1681A1 (en) 2-nitroimidazoles and preparation thereof
IL73876A0 (en) Acylamino-mitosanes and their preparation
GB2117757B (en) Alkylspectinomycins and their preparation
DE3367915D1 (en) Preparing 7-alkoxybenzofurans and intermediates used therein
GB2126230B (en) Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols preparation and use thereof
IL68831A (en) 2,2-dimethyl-3-aryl-cyclo-butanones and their preparation
GB2129001B (en) Epoxycarbacyclin derivatives their preparation and use
DE3374560D1 (en) Cyanoalkylpiperazines and methods for their preparation and use
DE3371073D1 (en) Beta-hydroxycyclopentylperoxide compounds and the use thereof
GB2141121B (en) 1-phenoxy-3-hydroxyindolyl-alkylamino-3-propanols and preparation
ZA849174B (en) Halonitriles and their preparation
DE3367919D1 (en) Furochromones and furobenzopyrans
KE3691A (en) 3-phenoxy-1-azetidinecarboxamides and their use and preparation
DE3163316D1 (en) Diacyloxyalkadienes and their preparation
IL68484A0 (en) Sulfonamidobenzophenones and their preparation

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930902