CH655103A5 - Azolderivate, verfahren zu ihrer herstellung und ihre verwendung. - Google Patents

Azolderivate, verfahren zu ihrer herstellung und ihre verwendung. Download PDF

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Publication number
CH655103A5
CH655103A5 CH1332/83A CH133283A CH655103A5 CH 655103 A5 CH655103 A5 CH 655103A5 CH 1332/83 A CH1332/83 A CH 1332/83A CH 133283 A CH133283 A CH 133283A CH 655103 A5 CH655103 A5 CH 655103A5
Authority
CH
Switzerland
Prior art keywords
formula
pharmaceutically acceptable
compounds
compound according
halogen
Prior art date
Application number
CH1332/83A
Other languages
German (de)
English (en)
Inventor
Anton Dr Stuetz
Helmut Dr Egger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH1332/83A priority Critical patent/CH655103A5/de
Priority to HU84780A priority patent/HUT36098A/hu
Priority to DK149784A priority patent/DK149784A/da
Priority to BE1/10974A priority patent/BE899073A/fr
Priority to FR8403733A priority patent/FR2542315B1/fr
Priority to DE19843408127 priority patent/DE3408127A1/de
Priority to NL8400730A priority patent/NL8400730A/nl
Priority to GB08405900A priority patent/GB2136801B/en
Priority to IT47817/84A priority patent/IT1199085B/it
Priority to PH30375A priority patent/PH24667A/en
Priority to SE8401321A priority patent/SE8401321L/xx
Priority to LU85245A priority patent/LU85245A1/fr
Priority to AU25475/84A priority patent/AU571494B2/en
Priority to AT0078884A priority patent/AT382868B/de
Priority to FI840968A priority patent/FI840968A/fi
Priority to ZA841782A priority patent/ZA841782B/xx
Priority to PL1984246600A priority patent/PL146072B1/pl
Priority to IL71203A priority patent/IL71203A/xx
Priority to ES530461A priority patent/ES8506639A1/es
Priority to CA000449330A priority patent/CA1242723A/en
Priority to PT78226A priority patent/PT78226B/pt
Priority to NZ207453A priority patent/NZ207453A/en
Priority to KR1019840001218A priority patent/KR890000377B1/ko
Priority to JP59046384A priority patent/JPS59175472A/ja
Priority to GR74070A priority patent/GR81869B/el
Publication of CH655103A5 publication Critical patent/CH655103A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CH1332/83A 1983-03-11 1983-03-11 Azolderivate, verfahren zu ihrer herstellung und ihre verwendung. CH655103A5 (de)

Priority Applications (25)

Application Number Priority Date Filing Date Title
CH1332/83A CH655103A5 (de) 1983-03-11 1983-03-11 Azolderivate, verfahren zu ihrer herstellung und ihre verwendung.
HU84780A HUT36098A (en) 1983-03-11 1984-02-27 Process for producing 1-phenyl-azol-ethylaminocarbonyl derivatives and utilzing them as pharmaceuticals
DK149784A DK149784A (da) 1983-03-11 1984-02-29 Azolderivater
BE1/10974A BE899073A (fr) 1983-03-11 1984-03-05 Nouveaux composes azoliques, leur preparation et leur utilisation comme antifongiques et fongicides
FR8403733A FR2542315B1 (fr) 1983-03-11 1984-03-05 Nouveaux composes azoliques, leur preparation et leur utilisation comme antifongiques et fongicides
DE19843408127 DE3408127A1 (de) 1983-03-11 1984-03-06 Neue azole, verfahren zu ihrer herstellung und ihre verwendung
NL8400730A NL8400730A (nl) 1983-03-11 1984-03-07 Nieuwe azolen, werkwijzen voor het bereiden daarvan en hun gebruik.
GB08405900A GB2136801B (en) 1983-03-11 1984-03-07 Fungicidal n-acyl-1-aryl-2-azolyl-ethylamines
IT47817/84A IT1199085B (it) 1983-03-11 1984-03-08 Composti azolici,loro preparazione e loro impiego come fungicidi
PH30375A PH24667A (en) 1983-03-11 1984-03-09 1-phenyl-2-(1h-imidazol-1-yl) ethanamines and 1-phenyl-2-(1,2,4-triazol-1yl) ethanamines and method of use thereof
SE8401321A SE8401321L (sv) 1983-03-11 1984-03-09 Nya azoler, forfaranden for deras framstellning och deras anvendning
LU85245A LU85245A1 (fr) 1983-03-11 1984-03-09 Nouveaux composes azoliques,leur preparation et leur utilisation comme antifongiques et fongicides
AU25475/84A AU571494B2 (en) 1983-03-11 1984-03-09 1- phenyl-2-azole-ethylamino-carbonyl derivatives
AT0078884A AT382868B (de) 1983-03-11 1984-03-09 Verfahren zur herstellung neuer azolderivate und deren salze
FI840968A FI840968A (fi) 1983-03-11 1984-03-09 Nya azoler, deras framstaellningsprocesser och deras anvaendning.
ZA841782A ZA841782B (en) 1983-03-11 1984-03-09 New azoles,processes for their preparation and their use
PL1984246600A PL146072B1 (en) 1983-03-11 1984-03-09 Method of obtaining novel carbonyl derivatives of 1-phenyl-2-diazolylethylamine and fungicide obtained thereby
IL71203A IL71203A (en) 1983-03-11 1984-03-09 Acylaminoethyl imidazole(triazole)derivatives,their preparation and pharmaceutical and plant fungicidal compositions containing them
ES530461A ES8506639A1 (es) 1983-03-11 1984-03-09 Procedimiento para preparar nuevos azoles
CA000449330A CA1242723A (en) 1983-03-11 1984-03-09 Azoles, processes for their preparation and their use
PT78226A PT78226B (en) 1983-03-11 1984-03-09 Process for the preparation of new azoles
NZ207453A NZ207453A (en) 1983-03-11 1984-03-09 1-phenyl-2-azole-ethylaminocarbonyl derivatives and pharmaceutical compositions
KR1019840001218A KR890000377B1 (ko) 1983-03-11 1984-03-10 아졸류의 제조방법
JP59046384A JPS59175472A (ja) 1983-03-11 1984-03-10 新規アゾ−ル類、その製法および用途
GR74070A GR81869B (fi) 1983-03-11 1984-03-12

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1332/83A CH655103A5 (de) 1983-03-11 1983-03-11 Azolderivate, verfahren zu ihrer herstellung und ihre verwendung.

Publications (1)

Publication Number Publication Date
CH655103A5 true CH655103A5 (de) 1986-03-27

Family

ID=4207992

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1332/83A CH655103A5 (de) 1983-03-11 1983-03-11 Azolderivate, verfahren zu ihrer herstellung und ihre verwendung.

Country Status (24)

Country Link
JP (1) JPS59175472A (fi)
KR (1) KR890000377B1 (fi)
AU (1) AU571494B2 (fi)
BE (1) BE899073A (fi)
CA (1) CA1242723A (fi)
CH (1) CH655103A5 (fi)
DE (1) DE3408127A1 (fi)
DK (1) DK149784A (fi)
ES (1) ES8506639A1 (fi)
FI (1) FI840968A (fi)
FR (1) FR2542315B1 (fi)
GB (1) GB2136801B (fi)
GR (1) GR81869B (fi)
HU (1) HUT36098A (fi)
IL (1) IL71203A (fi)
IT (1) IT1199085B (fi)
LU (1) LU85245A1 (fi)
NL (1) NL8400730A (fi)
NZ (1) NZ207453A (fi)
PH (1) PH24667A (fi)
PL (1) PL146072B1 (fi)
PT (1) PT78226B (fi)
SE (1) SE8401321L (fi)
ZA (1) ZA841782B (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8618188D0 (en) * 1986-07-25 1986-09-03 Ici Plc Diamine compounds
DE3644615A1 (de) * 1986-12-29 1988-07-07 Lentia Gmbh Imidazol- und triazolderivate zur verwendung als antimykotische mittel
DE3644616A1 (de) * 1986-12-29 1988-07-07 Lentia Gmbh Imidazolderivate, verfahren zur herstellung und deren verwendung
US5252594A (en) * 1992-06-17 1993-10-12 Rohm And Haas Company Fungicidal (2-aryl-2-substituted)ethyl-1,2,4-triazoles
US5358939A (en) * 1992-06-25 1994-10-25 Rohm And Haas Company Fungicidal 2-aryl-2,2-disubstituted ethyl-1,2,4-triazoles
DE4412358A1 (de) * 1994-04-11 1995-10-12 Bayer Ag Cyclopropyl-ethyl-azole
GB9409882D0 (en) * 1994-05-18 1994-07-06 Sandoz Ltd Organic compounds
JP3214987B2 (ja) * 1994-09-05 2001-10-02 日本碍子株式会社 半導体装置およびその製造方法
US7125997B2 (en) * 2002-12-20 2006-10-24 Irm Llc Differential tumor cytotoxicity compounds and compositions
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
KR101192861B1 (ko) 2004-05-07 2012-10-19 얀센 파마슈티카 엔.브이. １１-베타 하이드록시스테로이드 탈수소효소 저해제로서의피롤리딘-２-온 및 피페리딘-２-온 유도체
JP5208505B2 (ja) 2004-08-30 2013-06-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ １１−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのｎ−２アダマンタニル−２−フェノキシ−アセトアミド誘導体
AU2005279209B2 (en) 2004-08-30 2011-03-24 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-BETA hydroxysteroid dehydrogenase inhibitors
DE602005017159D1 (de) 2004-08-30 2009-11-26 Janssen Pharmaceutica Nv Oxysteroid-dehydrogenase-inhibitoren
WO2006034338A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
WO2006034315A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
US7829712B2 (en) 2004-09-20 2010-11-09 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
BRPI0515482A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
TW200624427A (en) 2004-09-20 2006-07-16 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
CN101083994A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其用作硬脂酰CoA去饱和酶抑制剂的用途
BRPI0611187A2 (pt) 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
CN104530038A (zh) * 2014-12-10 2015-04-22 沈阳药科大学 酰胺咪唑类衍生物及其用途
CN112142673B (zh) * 2020-09-18 2023-06-30 聊城大学 芳基烯烃唑类衍生物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
CA1189857A (en) * 1981-03-27 1985-07-02 Janssen Pharmaceutica Naamloze Vennootschap Antimicrobial triazole derivatives
AU8314482A (en) * 1981-05-19 1982-11-25 Imperial Chemical Industries Plc 3-triazolyl(imidazolyl)-2,2 bis phenyl-propionamides
EP0117462A3 (en) * 1983-02-28 1986-08-20 American Cyanamid Company N-(2-4-(1h-imidazol-1-yl)alkyl)arylamides

Also Published As

Publication number Publication date
FR2542315B1 (fr) 1986-02-07
KR890000377B1 (ko) 1989-03-15
DK149784A (da) 1984-09-12
NZ207453A (en) 1987-09-30
BE899073A (fr) 1984-09-05
LU85245A1 (fr) 1984-11-14
GB2136801B (en) 1987-03-04
PT78226B (en) 1986-07-15
PH24667A (en) 1990-09-07
ES530461A0 (es) 1985-07-16
AU571494B2 (en) 1988-04-21
KR850006386A (ko) 1985-10-05
IL71203A (en) 1988-10-31
ZA841782B (en) 1985-10-30
HUT36098A (en) 1985-08-28
AU2547584A (en) 1984-09-13
IT1199085B (it) 1988-12-30
ES8506639A1 (es) 1985-07-16
FR2542315A1 (fr) 1984-09-14
PL146072B1 (en) 1988-12-31
DE3408127A1 (de) 1984-09-13
IT8447817A0 (it) 1984-03-08
CA1242723A (en) 1988-10-04
SE8401321D0 (sv) 1984-03-09
JPS59175472A (ja) 1984-10-04
PL246600A1 (en) 1985-03-12
PT78226A (en) 1984-04-01
GB2136801A (en) 1984-09-26
GR81869B (fi) 1984-12-12
DK149784D0 (da) 1984-02-29
NL8400730A (nl) 1984-10-01
FI840968A (fi) 1984-09-12
GB8405900D0 (en) 1984-04-11
SE8401321L (sv) 1984-09-12
IL71203A0 (en) 1984-06-29
FI840968A0 (fi) 1984-03-09

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