CH647515A5 - Substituierte s-triazinone bzw. thione. - Google Patents
Substituierte s-triazinone bzw. thione. Download PDFInfo
- Publication number
- CH647515A5 CH647515A5 CH10138/79A CH1013879A CH647515A5 CH 647515 A5 CH647515 A5 CH 647515A5 CH 10138/79 A CH10138/79 A CH 10138/79A CH 1013879 A CH1013879 A CH 1013879A CH 647515 A5 CH647515 A5 CH 647515A5
- Authority
- CH
- Switzerland
- Prior art keywords
- lower alkyl
- triazin
- amidino
- dihydro
- acceptable salts
- Prior art date
Links
- OPOJRMTZHYUKLY-UHFFFAOYSA-N 1h-1,3,5-triazin-2-one Chemical class O=C1N=CN=CN1 OPOJRMTZHYUKLY-UHFFFAOYSA-N 0.000 title claims description 17
- 150000001875 compounds Chemical class 0.000 claims description 107
- 125000000217 alkyl group Chemical group 0.000 claims description 52
- 238000012360 testing method Methods 0.000 claims description 40
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 38
- -1 cyano, carboxyl Chemical group 0.000 claims description 37
- 150000003839 salts Chemical class 0.000 claims description 36
- 238000002360 preparation method Methods 0.000 claims description 34
- 231100000252 nontoxic Toxicity 0.000 claims description 30
- 230000003000 nontoxic effect Effects 0.000 claims description 30
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- OKGXJRGLYVRVNE-UHFFFAOYSA-N diaminomethylidenethiourea Chemical compound NC(N)=NC(N)=S OKGXJRGLYVRVNE-UHFFFAOYSA-N 0.000 claims description 8
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 claims description 8
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- RBYFKCAAFQIZAQ-UHFFFAOYSA-N 1h-1,3,5-triazine-2-thione Chemical compound S=C1N=CN=CN1 RBYFKCAAFQIZAQ-UHFFFAOYSA-N 0.000 claims description 5
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- 125000004433 nitrogen atom Chemical group N* 0.000 claims 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 6
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical group C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 claims 5
- 125000002252 acyl group Chemical group 0.000 claims 5
- 125000004423 acyloxy group Chemical group 0.000 claims 5
- 125000003342 alkenyl group Chemical group 0.000 claims 5
- 125000000304 alkynyl group Chemical group 0.000 claims 5
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 5
- 125000005843 halogen group Chemical group 0.000 claims 5
- 125000004442 acylamino group Chemical group 0.000 claims 4
- 229910052799 carbon Inorganic materials 0.000 claims 4
- 238000004587 chromatography analysis Methods 0.000 claims 4
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 claims 4
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims 4
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 3
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- JIHQDMXYYFUGFV-UHFFFAOYSA-N 1,3,5-triazine Chemical class C1=NC=NC=N1 JIHQDMXYYFUGFV-UHFFFAOYSA-N 0.000 claims 2
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- UJKUJXVZLUTEAZ-UHFFFAOYSA-N n,n-dimethylformamide;dimethyl sulfate Chemical compound CN(C)C=O.COS(=O)(=O)OC UJKUJXVZLUTEAZ-UHFFFAOYSA-N 0.000 claims 2
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- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 claims 2
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- JALZUVLKZSNFIH-UHFFFAOYSA-N 1-(2,6-dimethylphenyl)-4-(methylamino)-1,3,5-triazin-2-one;methanesulfonic acid Chemical compound CS(O)(=O)=O.O=C1N=C(NC)N=CN1C1=C(C)C=CC=C1C JALZUVLKZSNFIH-UHFFFAOYSA-N 0.000 claims 1
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- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
- C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/959,611 US4246409A (en) | 1978-11-13 | 1978-11-13 | Triazinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH647515A5 true CH647515A5 (de) | 1985-01-31 |
Family
ID=25502213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH10138/79A CH647515A5 (de) | 1978-11-13 | 1979-11-13 | Substituierte s-triazinone bzw. thione. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4246409A (en, 2012) |
| JP (1) | JPS5572174A (en, 2012) |
| AR (1) | AR226547A1 (en, 2012) |
| AU (1) | AU530790B2 (en, 2012) |
| BE (1) | BE879990A (en, 2012) |
| CA (1) | CA1136136A (en, 2012) |
| CH (1) | CH647515A5 (en, 2012) |
| DE (1) | DE2945701A1 (en, 2012) |
| ES (1) | ES485929A0 (en, 2012) |
| FR (1) | FR2441617A1 (en, 2012) |
| GB (1) | GB2039891B (en, 2012) |
| HU (1) | HU180289B (en, 2012) |
| IT (1) | IT1193334B (en, 2012) |
| MX (1) | MX6832E (en, 2012) |
| NL (1) | NL7908287A (en, 2012) |
| PH (1) | PH17430A (en, 2012) |
| ZA (1) | ZA796079B (en, 2012) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4387225A (en) * | 1981-01-15 | 1983-06-07 | William H. Rorer, Inc. | Heterocyclic alkylene triazinones |
| US4452980A (en) * | 1981-01-15 | 1984-06-05 | William H. Rorer, Inc. | Triazinones |
| US4443456A (en) * | 1981-05-12 | 1984-04-17 | William H. Rorer, Inc. | Pyridyl alkylene amidinoureas |
| US4460585A (en) * | 1981-07-06 | 1984-07-17 | William H. Rorer, Inc. | 1-Aryl-4-hydrazinyl-s-triazin-2-ones |
| US4406897A (en) * | 1981-07-06 | 1983-09-27 | William H. Rorer, Inc. | 6-Aryl-4-hydrazinyl-s-triazin-2-ones |
| USRE33125E (en) * | 1981-07-06 | 1989-12-05 | Rorer Pharmaceutical Corporation | 3- and 5-[3-(1-arylureido)]-1,2,4-triazoles |
| EP0073276A1 (en) * | 1981-08-24 | 1983-03-09 | Rorer International (Overseas) Inc. | A method of increasing the feed efficiency of animals, and compositions for use in such a method |
| US4562188A (en) * | 1984-01-13 | 1985-12-31 | William H. Rorer, Inc. | Triazinones for treating irritable bowel syndrome |
| WO2011109383A1 (en) * | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy -4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| WO2015050212A1 (ja) * | 2013-10-02 | 2015-04-09 | 日産化学工業株式会社 | Ｔ型カルシウムチャネル阻害剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1287910A (en, 2012) * | 1968-12-19 | 1972-09-06 | ||
| IL42103A (en) * | 1972-05-24 | 1976-05-31 | Du Pont | 6-amino-s-triazine-2,4-(1h,3h)-diones and corresponding 4-thio compounds,their preparation and their use as herbicides |
| US4068081A (en) * | 1974-02-15 | 1978-01-10 | Imperial Chemical Industries Limited | Δ-Triazine-2,6-dione |
-
1978
- 1978-11-13 US US05/959,611 patent/US4246409A/en not_active Expired - Lifetime
-
1979
- 1979-11-07 CA CA000339405A patent/CA1136136A/en not_active Expired
- 1979-11-12 PH PH23273A patent/PH17430A/en unknown
- 1979-11-12 AU AU52735/79A patent/AU530790B2/en not_active Ceased
- 1979-11-12 ZA ZA00796079A patent/ZA796079B/xx unknown
- 1979-11-13 MX MX798483U patent/MX6832E/es unknown
- 1979-11-13 BE BE0/198083A patent/BE879990A/fr not_active IP Right Cessation
- 1979-11-13 DE DE19792945701 patent/DE2945701A1/de not_active Ceased
- 1979-11-13 HU HU79RO1042A patent/HU180289B/hu unknown
- 1979-11-13 GB GB7939190A patent/GB2039891B/en not_active Expired
- 1979-11-13 ES ES485929A patent/ES485929A0/es active Granted
- 1979-11-13 NL NL7908287A patent/NL7908287A/nl not_active Application Discontinuation
- 1979-11-13 CH CH10138/79A patent/CH647515A5/de not_active IP Right Cessation
- 1979-11-13 IT IT27243/79A patent/IT1193334B/it active
- 1979-11-13 JP JP14697079A patent/JPS5572174A/ja active Granted
- 1979-11-13 FR FR7927874A patent/FR2441617A1/fr active Granted
- 1979-11-18 AR AR278877A patent/AR226547A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| AU530790B2 (en) | 1983-07-28 |
| GB2039891A (en) | 1980-08-20 |
| IT7927243A0 (it) | 1979-11-13 |
| ZA796079B (en) | 1980-12-31 |
| US4246409A (en) | 1981-01-20 |
| CA1136136A (en) | 1982-11-23 |
| PH17430A (en) | 1984-08-20 |
| NL7908287A (nl) | 1980-05-16 |
| ES8100278A1 (es) | 1980-11-01 |
| MX6832E (es) | 1986-08-15 |
| BE879990A (fr) | 1980-05-13 |
| FR2441617B1 (en, 2012) | 1983-08-26 |
| AU5273579A (en) | 1980-05-22 |
| ES485929A0 (es) | 1980-11-01 |
| AR226547A1 (es) | 1982-07-30 |
| IT1193334B (it) | 1988-06-15 |
| JPS5572174A (en) | 1980-05-30 |
| JPS6365664B2 (en, 2012) | 1988-12-16 |
| DE2945701A1 (de) | 1980-08-07 |
| HU180289B (en) | 1983-02-28 |
| FR2441617A1 (fr) | 1980-06-13 |
| GB2039891B (en) | 1983-05-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |