CH646953A5 - 1(2h)-isochinolone und deren salze mit saeuren, verfahren zu ihrer herstellung und sie enthaltende arzneipraeparate. - Google Patents

1(2h)-isochinolone und deren salze mit saeuren, verfahren zu ihrer herstellung und sie enthaltende arzneipraeparate. Download PDF

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Publication number
CH646953A5
CH646953A5 CH632480A CH632480A CH646953A5 CH 646953 A5 CH646953 A5 CH 646953A5 CH 632480 A CH632480 A CH 632480A CH 632480 A CH632480 A CH 632480A CH 646953 A5 CH646953 A5 CH 646953A5
Authority
CH
Switzerland
Prior art keywords
formula
isoquinolone
mixture
recrystallized
phenyl
Prior art date
Application number
CH632480A
Other languages
German (de)
English (en)
Inventor
Shigeo Senda
Osamu Ohtani
Eiichi Katho
Hidekazu Miyake
Khosuke Fujiwara
Original Assignee
Maruko Pharmaceutical Co
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruko Pharmaceutical Co, Taiho Pharmaceutical Co Ltd filed Critical Maruko Pharmaceutical Co
Publication of CH646953A5 publication Critical patent/CH646953A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH632480A 1979-08-21 1980-08-21 1(2h)-isochinolone und deren salze mit saeuren, verfahren zu ihrer herstellung und sie enthaltende arzneipraeparate. CH646953A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10549779A JPS5677261A (en) 1979-08-21 1979-08-21 1 2h isoquinolone derivative and its acid addition salt

Publications (1)

Publication Number Publication Date
CH646953A5 true CH646953A5 (de) 1984-12-28

Family

ID=14409228

Family Applications (1)

Application Number Title Priority Date Filing Date
CH632480A CH646953A5 (de) 1979-08-21 1980-08-21 1(2h)-isochinolone und deren salze mit saeuren, verfahren zu ihrer herstellung und sie enthaltende arzneipraeparate.

Country Status (10)

Country Link
JP (1) JPS5677261A (it)
AU (1) AU532023B2 (it)
CA (1) CA1153763A (it)
CH (1) CH646953A5 (it)
DE (1) DE3031574A1 (it)
ES (1) ES494891A0 (it)
FR (1) FR2463766A1 (it)
GB (1) GB2058783B (it)
IT (1) IT1188988B (it)
NL (1) NL8004736A (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2098980B (en) * 1981-03-28 1985-05-15 Taiho Pharmaceutical Co Ltd 1(2h)-isoquinolone compounds and acid addition salts thereof
JPS58164577A (ja) * 1982-03-24 1983-09-29 Taiho Yakuhin Kogyo Kk ４―ベンジル―１―（２ｈ）イソキノロン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils
SE368009B (it) * 1971-09-16 1974-06-17 Kabi Ab
US3928612A (en) * 1974-10-02 1975-12-23 American Home Prod 1,2-Dihydro- and 1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid derivatives as anti-allergic agents

Also Published As

Publication number Publication date
DE3031574A1 (de) 1981-03-12
CA1153763A (en) 1983-09-13
AU532023B2 (en) 1983-09-15
AU6160980A (en) 1981-04-09
FR2463766A1 (fr) 1981-02-27
GB2058783A (en) 1981-04-15
FR2463766B1 (it) 1983-09-02
ES8106501A1 (es) 1981-09-01
ES494891A0 (es) 1981-09-01
GB2058783B (en) 1983-04-07
IT8049519A1 (it) 1982-02-19
IT1188988B (it) 1988-01-28
JPS5677261A (en) 1981-06-25
NL8004736A (nl) 1981-02-24
IT8049519A0 (it) 1980-08-19

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PL Patent ceased