CH639659A5 - Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. - Google Patents
Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. Download PDFInfo
- Publication number
- CH639659A5 CH639659A5 CH1283578A CH1283578A CH639659A5 CH 639659 A5 CH639659 A5 CH 639659A5 CH 1283578 A CH1283578 A CH 1283578A CH 1283578 A CH1283578 A CH 1283578A CH 639659 A5 CH639659 A5 CH 639659A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- formula
- ch2ch
- new
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1978-12-18 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
DE19792949491 DE2949491A1 (de) | 1978-12-18 | 1979-12-08 | 1,4-dihydropyridine, ihre herstellung und verwendung |
SE7910188A SE445219B (sv) | 1978-12-18 | 1979-12-11 | 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition |
BE1/9643A BE880591A (fr) | 1978-12-18 | 1979-12-13 | Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments |
IT51095/79A IT1164097B (it) | 1978-12-18 | 1979-12-14 | "1,4-di idropiridine loro preparazione e loro applicazione come medicamenti" |
NL7909024A NL193066C (nl) | 1978-12-18 | 1979-12-14 | Methyl,isopropyl-4-(2,1,3-benzoxadiazool-4-yl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylaat en farmaceutisch preparaat dat deze verbinding bevat. |
GB7943113A GB2037766B (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines their preparation and pharmaceutical compositions containing them |
CY1321A CY1321A (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines their preparation and pharmaceutical compositions containing them |
GB08215988A GB2103203B (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines, their preparation and pharmaceutical compositions containing them |
AU53896/79A AU536055B2 (en) | 1978-12-18 | 1979-12-17 | Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole |
FR7930829A FR2444681A1 (fr) | 1978-12-18 | 1979-12-17 | Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments |
NZ192422A NZ192422A (en) | 1978-12-18 | 1979-12-17 | Benzoxadiazoles and benzothiadiazoles with 1,4-dihydropyridine moiety pharmaceutical compositions |
IE2445/79A IE49496B1 (en) | 1978-12-18 | 1979-12-17 | A 1,4-dihydropyridine derivative,its preparation and pharmaceutical compositions containing it |
JP16396579A JPS5583783A (en) | 1978-12-18 | 1979-12-17 | 1*44dihydropyridine derivative |
IE1165/83A IE49497B1 (en) | 1978-12-18 | 1979-12-17 | 1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them |
ZA00796842A ZA796842B (en) | 1978-12-18 | 1979-12-18 | 1,4-dihydropyridines, their preparation and pharmaceutical compositions containing them |
PH24383A PH19536A (en) | 1977-06-20 | 1980-08-01 | Benzoxadiazoles and benzothiadiazoles and pharmaceutical composition containing them |
NZ199437A NZ199437A (en) | 1978-12-18 | 1982-01-07 | 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3-methoxycarbonylpyridine-5-carboxylic acid isopropyl ester and pharmaceutical compositions |
US06/359,751 US4466972A (en) | 1977-06-20 | 1982-03-19 | Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them |
SG975/85A SG97585G (en) | 1978-12-18 | 1985-12-20 | A 1,4-dihydropyridine derivative,its preparation and pharmaceutical compositions containing it |
MY130/85A MY8500130A (en) | 1978-12-18 | 1985-12-30 | A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it |
KE3593A KE3593A (en) | 1978-12-18 | 1986-01-08 | A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it |
HK160/86A HK16086A (en) | 1978-12-18 | 1986-03-06 | A 1,4-dihydropyridine derivate its preparation and pharmaceutical compositions containing it |
NL990014C NL990014I1 (nl) | 1978-12-18 | 1999-05-11 | Methyl, isopropyl-4-(2,1,3-benzoxadiazool-4-yl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylaat en farmaceutisch preparaat dat deze verbinding bevat. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1978-12-18 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
Publications (1)
Publication Number | Publication Date |
---|---|
CH639659A5 true CH639659A5 (de) | 1983-11-30 |
Family
ID=4386824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1977-06-20 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5583783A (xx) |
AU (1) | AU536055B2 (xx) |
BE (1) | BE880591A (xx) |
CH (1) | CH639659A5 (xx) |
CY (1) | CY1321A (xx) |
DE (1) | DE2949491A1 (xx) |
FR (1) | FR2444681A1 (xx) |
GB (2) | GB2037766B (xx) |
HK (1) | HK16086A (xx) |
IE (1) | IE49496B1 (xx) |
IT (1) | IT1164097B (xx) |
KE (1) | KE3593A (xx) |
MY (1) | MY8500130A (xx) |
NL (2) | NL193066C (xx) |
NZ (1) | NZ192422A (xx) |
SE (1) | SE445219B (xx) |
SG (1) | SG97585G (xx) |
ZA (1) | ZA796842B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3022030A1 (de) * | 1980-06-12 | 1981-12-17 | Bayer Ag, 5090 Leverkusen | 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel |
CH655658B (xx) * | 1980-09-18 | 1986-05-15 | ||
DE3269219D1 (en) * | 1981-11-17 | 1986-03-27 | Fisons Plc | Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals |
ZA83959B (en) * | 1982-03-10 | 1984-09-26 | Sandoz Ltd | 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
US4414213A (en) * | 1982-03-22 | 1983-11-08 | Mead Johnson & Company | Dihydropyridyl cyclic imidate esters and their pharmaceutical use |
IL68975A (en) * | 1982-06-15 | 1987-01-30 | Sandoz Ag | 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them |
FR2528431B1 (fr) * | 1982-06-15 | 1986-01-10 | Sandoz Sa | Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments |
JPS5978186A (ja) * | 1982-10-27 | 1984-05-04 | Yoshitomi Pharmaceut Ind Ltd | 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体 |
US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
HU198844B (en) * | 1984-06-14 | 1989-12-28 | Sandoz Ag | Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient |
US5260321A (en) * | 1984-11-12 | 1993-11-09 | Sandoz Ltd. | Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins |
HU197201B (en) * | 1985-10-01 | 1989-03-28 | Sandoz Ag | Process for producing oral pharmaceutical compositions of controlled solubility of the active components |
DE3542794A1 (de) * | 1985-12-04 | 1987-06-11 | Bayer Ag | Antihypertensives kombinationspraeparat |
GB8626217D0 (en) * | 1986-11-03 | 1986-12-03 | Sandoz Ltd | Pharmaceutical compositions |
US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
KR940003492B1 (ko) * | 1988-10-27 | 1994-04-23 | 주식회사 유한양행 | 1,4-디하이드로피리딘유도체 및 그의 제조방법 |
DE4222770A1 (de) * | 1992-07-10 | 1994-01-13 | Bayer Ag | Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine |
EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
AU2003269482A1 (en) * | 2003-09-10 | 2005-03-29 | Shasun Chemicals And Drugs Limited | Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde |
CN103613584B (zh) * | 2013-11-27 | 2016-04-27 | 沈阳药科大学 | 一种伊拉地平合成产物后处理的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
FR2320750A1 (fr) * | 1975-08-12 | 1977-03-11 | Hexachimie | Dihydro-1,4 pyridines et leur application therapeutique |
DE2616991A1 (de) * | 1976-04-17 | 1977-10-27 | Bayer Ag | Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPS5373327A (en) * | 1976-12-13 | 1978-06-29 | Matsushita Electric Ind Co Ltd | Power source system |
FI64938C (fi) * | 1977-06-20 | 1984-02-10 | Sandoz Ag | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat |
-
1978
- 1978-12-18 CH CH1283578A patent/CH639659A5/de not_active IP Right Cessation
-
1979
- 1979-12-08 DE DE19792949491 patent/DE2949491A1/de active Granted
- 1979-12-11 SE SE7910188A patent/SE445219B/sv not_active IP Right Cessation
- 1979-12-13 BE BE1/9643A patent/BE880591A/fr not_active IP Right Cessation
- 1979-12-14 GB GB7943113A patent/GB2037766B/en not_active Expired
- 1979-12-14 NL NL7909024A patent/NL193066C/nl not_active IP Right Cessation
- 1979-12-14 GB GB08215988A patent/GB2103203B/en not_active Expired
- 1979-12-14 CY CY1321A patent/CY1321A/xx unknown
- 1979-12-14 IT IT51095/79A patent/IT1164097B/it active Protection Beyond IP Right Term
- 1979-12-17 NZ NZ192422A patent/NZ192422A/xx unknown
- 1979-12-17 FR FR7930829A patent/FR2444681A1/fr active Granted
- 1979-12-17 IE IE2445/79A patent/IE49496B1/en not_active IP Right Cessation
- 1979-12-17 AU AU53896/79A patent/AU536055B2/en not_active Expired
- 1979-12-17 JP JP16396579A patent/JPS5583783A/ja active Granted
- 1979-12-18 ZA ZA00796842A patent/ZA796842B/xx unknown
-
1985
- 1985-12-20 SG SG975/85A patent/SG97585G/en unknown
- 1985-12-30 MY MY130/85A patent/MY8500130A/xx unknown
-
1986
- 1986-01-08 KE KE3593A patent/KE3593A/xx unknown
- 1986-03-06 HK HK160/86A patent/HK16086A/xx not_active IP Right Cessation
-
1999
- 1999-05-11 NL NL990014C patent/NL990014I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
NL193066C (nl) | 1998-09-08 |
GB2037766B (en) | 1983-02-16 |
NL7909024A (nl) | 1980-06-20 |
JPS5583783A (en) | 1980-06-24 |
NZ192422A (en) | 1982-09-14 |
KE3593A (en) | 1986-02-07 |
SE445219B (sv) | 1986-06-09 |
GB2103203A (en) | 1983-02-16 |
SE7910188L (sv) | 1980-06-19 |
AU536055B2 (en) | 1984-04-19 |
IE49496B1 (en) | 1985-10-16 |
IE792445L (en) | 1980-06-18 |
HK16086A (en) | 1986-03-14 |
FR2444681B1 (xx) | 1982-10-29 |
NL990014I1 (nl) | 1999-07-01 |
IT7951095A0 (it) | 1979-12-14 |
MY8500130A (en) | 1985-12-31 |
ZA796842B (en) | 1981-07-29 |
NL193066B (nl) | 1998-05-06 |
CY1321A (en) | 1986-06-27 |
JPH0369910B2 (xx) | 1991-11-05 |
FR2444681A1 (fr) | 1980-07-18 |
AU5389679A (en) | 1980-06-26 |
IT1164097B (it) | 1987-04-08 |
SG97585G (en) | 1986-07-18 |
GB2103203B (en) | 1983-06-08 |
DE2949491C2 (xx) | 1988-10-27 |
BE880591A (fr) | 1980-06-13 |
GB2037766A (en) | 1980-07-16 |
DE2949491A1 (de) | 1980-06-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PFA | Name/firm changed |
Owner name: SANDOZ AG TRANSFER- NOVARTIS AG |
|
PL | Patent ceased |