CH632487A5 - Process for preparing novel cyanoacetanilide derivatives - Google Patents

Process for preparing novel cyanoacetanilide derivatives Download PDF

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Publication number
CH632487A5
CH632487A5 CH1560476A CH1560476A CH632487A5 CH 632487 A5 CH632487 A5 CH 632487A5 CH 1560476 A CH1560476 A CH 1560476A CH 1560476 A CH1560476 A CH 1560476A CH 632487 A5 CH632487 A5 CH 632487A5
Authority
CH
Switzerland
Prior art keywords
formula
group
anilide
cyanoacetic
methyl
Prior art date
Application number
CH1560476A
Other languages
German (de)
English (en)
Inventor
Klaus-Dieter Dr Kampe
Hartmut Dr Ertel
Guenther Dr Heubach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752555685 external-priority patent/DE2555685A1/de
Priority claimed from DE19752557003 external-priority patent/DE2557003A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH632487A5 publication Critical patent/CH632487A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH1560476A 1975-12-11 1976-12-10 Process for preparing novel cyanoacetanilide derivatives CH632487A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752555685 DE2555685A1 (de) 1975-12-11 1975-12-11 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DE19752557003 DE2557003A1 (de) 1975-12-18 1975-12-18 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel

Publications (1)

Publication Number Publication Date
CH632487A5 true CH632487A5 (en) 1982-10-15

Family

ID=25769723

Family Applications (6)

Application Number Title Priority Date Filing Date
CH1560476A CH632487A5 (en) 1975-12-11 1976-12-10 Process for preparing novel cyanoacetanilide derivatives
CH250481A CH630341A5 (en) 1975-12-11 1981-04-14 Process for the preparation of novel cyanoacetic anilide derivatives.
CH250881A CH629757A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives
CH250681A CH630342A5 (en) 1975-12-11 1981-04-14 Process for the preparation of novel cyanoacetic acid anilide derivatives.
CH250581A CH629755A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives
CH250781A CH629756A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives

Family Applications After (5)

Application Number Title Priority Date Filing Date
CH250481A CH630341A5 (en) 1975-12-11 1981-04-14 Process for the preparation of novel cyanoacetic anilide derivatives.
CH250881A CH629757A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives
CH250681A CH630342A5 (en) 1975-12-11 1981-04-14 Process for the preparation of novel cyanoacetic acid anilide derivatives.
CH250581A CH629755A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives
CH250781A CH629756A5 (en) 1975-12-11 1981-04-14 Process for the preparation of cyanoacetanilide derivatives

Country Status (12)

Country Link
JP (1) JPS5273830A (fr)
CA (1) CA1092133A (fr)
CH (6) CH632487A5 (fr)
DK (1) DK545976A (fr)
ES (6) ES453963A2 (fr)
FR (1) FR2334350A2 (fr)
GB (1) GB1571990A (fr)
IE (1) IE44047B1 (fr)
IT (1) IT1124789B (fr)
LU (1) LU76354A1 (fr)
MX (1) MX4758E (fr)
NL (1) NL7613547A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3361451D1 (en) * 1982-03-05 1986-01-23 Fbc Ltd Fungicidal cyanopropenoates and compositions containing them
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619433D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
US6355678B1 (en) 1998-06-29 2002-03-12 Parker Hughes Institute Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
WO2010013159A1 (fr) * 2008-07-29 2010-02-04 Alembic Limited Procédé de préparation du tériflunomide

Also Published As

Publication number Publication date
DK545976A (da) 1977-06-12
ES475110A1 (es) 1979-05-01
IE44047L (en) 1977-06-11
ES453963A2 (es) 1978-05-01
ES466542A2 (es) 1979-01-16
FR2334350A2 (fr) 1977-07-08
IE44047B1 (en) 1981-07-29
ES475111A1 (es) 1979-05-01
GB1571990A (en) 1980-07-23
ES475108A2 (es) 1979-08-01
LU76354A1 (fr) 1977-06-24
NL7613547A (nl) 1977-06-14
MX4758E (es) 1982-09-03
CH629755A5 (en) 1982-05-14
CH629756A5 (en) 1982-05-14
JPS5273830A (en) 1977-06-21
CH629757A5 (en) 1982-05-14
ES475109A1 (es) 1979-04-16
CA1092133A (fr) 1980-12-23
CH630342A5 (en) 1982-06-15
IT1124789B (it) 1986-05-14
CH630341A5 (en) 1982-06-15
FR2334350B2 (fr) 1980-03-07

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Legal Events

Date Code Title Description
PL Patent ceased