CA1092133A - Derives anilides de l'acide cyanoacetique, procede de preparation et composes les contenant - Google Patents

Derives anilides de l'acide cyanoacetique, procede de preparation et composes les contenant

Info

Publication number
CA1092133A
CA1092133A CA267,670A CA267670A CA1092133A CA 1092133 A CA1092133 A CA 1092133A CA 267670 A CA267670 A CA 267670A CA 1092133 A CA1092133 A CA 1092133A
Authority
CA
Canada
Prior art keywords
formula
anilide
acid
cyanoacetic acid
hydroxyethylidene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA267,670A
Other languages
English (en)
Inventor
Klaus-Dieter Kampe
Hartmut Ertel
Gunther Heubach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752555685 external-priority patent/DE2555685A1/de
Priority claimed from DE19752557003 external-priority patent/DE2557003A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1092133A publication Critical patent/CA1092133A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA267,670A 1975-12-11 1976-12-10 Derives anilides de l'acide cyanoacetique, procede de preparation et composes les contenant Expired CA1092133A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19752555685 DE2555685A1 (de) 1975-12-11 1975-12-11 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
DEP2555685.8 1975-12-11
DEP2557003.0 1975-12-18
DE19752557003 DE2557003A1 (de) 1975-12-18 1975-12-18 Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel

Publications (1)

Publication Number Publication Date
CA1092133A true CA1092133A (fr) 1980-12-23

Family

ID=25769723

Family Applications (1)

Application Number Title Priority Date Filing Date
CA267,670A Expired CA1092133A (fr) 1975-12-11 1976-12-10 Derives anilides de l'acide cyanoacetique, procede de preparation et composes les contenant

Country Status (12)

Country Link
JP (1) JPS5273830A (fr)
CA (1) CA1092133A (fr)
CH (6) CH632487A5 (fr)
DK (1) DK545976A (fr)
ES (6) ES453963A2 (fr)
FR (1) FR2334350A2 (fr)
GB (1) GB1571990A (fr)
IE (1) IE44047B1 (fr)
IT (1) IT1124789B (fr)
LU (1) LU76354A1 (fr)
MX (1) MX4758E (fr)
NL (1) NL7613547A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3361451D1 (en) * 1982-03-05 1986-01-23 Fbc Ltd Fungicidal cyanopropenoates and compositions containing them
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619433D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
US6355678B1 (en) 1998-06-29 2002-03-12 Parker Hughes Institute Inhibitors of the EGF-receptor tyrosine kinase and methods for their use
WO2010013159A1 (fr) * 2008-07-29 2010-02-04 Alembic Limited Procédé de préparation du tériflunomide

Also Published As

Publication number Publication date
DK545976A (da) 1977-06-12
ES475110A1 (es) 1979-05-01
IE44047L (en) 1977-06-11
CH632487A5 (en) 1982-10-15
ES453963A2 (es) 1978-05-01
ES466542A2 (es) 1979-01-16
FR2334350A2 (fr) 1977-07-08
IE44047B1 (en) 1981-07-29
ES475111A1 (es) 1979-05-01
GB1571990A (en) 1980-07-23
ES475108A2 (es) 1979-08-01
LU76354A1 (fr) 1977-06-24
NL7613547A (nl) 1977-06-14
MX4758E (es) 1982-09-03
CH629755A5 (en) 1982-05-14
CH629756A5 (en) 1982-05-14
JPS5273830A (en) 1977-06-21
CH629757A5 (en) 1982-05-14
ES475109A1 (es) 1979-04-16
CH630342A5 (en) 1982-06-15
IT1124789B (it) 1986-05-14
CH630341A5 (en) 1982-06-15
FR2334350B2 (fr) 1980-03-07

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Legal Events

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