CH623811A5 - - Google Patents

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Publication number
CH623811A5
CH623811A5 CH1494276A CH1494276A CH623811A5 CH 623811 A5 CH623811 A5 CH 623811A5 CH 1494276 A CH1494276 A CH 1494276A CH 1494276 A CH1494276 A CH 1494276A CH 623811 A5 CH623811 A5 CH 623811A5
Authority
CH
Switzerland
Prior art keywords
spiro
carbon atoms
group
indoline
cyclopropan
Prior art date
Application number
CH1494276A
Other languages
German (de)
English (en)
Inventor
Shunsaku Noguchi
Saburo Takei
Yasuhiko Kawano
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH623811A5 publication Critical patent/CH623811A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH1494276A 1975-11-26 1976-11-26 CH623811A5 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50141748A JPS5265267A (en) 1975-11-26 1975-11-26 Synthesis of spiro compounds

Publications (1)

Publication Number Publication Date
CH623811A5 true CH623811A5 (hu) 1981-06-30

Family

ID=15299270

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1494276A CH623811A5 (hu) 1975-11-26 1976-11-26

Country Status (12)

Country Link
US (1) US4105670A (hu)
JP (1) JPS5265267A (hu)
AU (1) AU499472B2 (hu)
BE (1) BE848766A (hu)
CA (1) CA1091656A (hu)
CH (1) CH623811A5 (hu)
DE (1) DE2653477A1 (hu)
DK (1) DK526476A (hu)
FR (1) FR2362125A1 (hu)
GB (1) GB1570596A (hu)
NL (1) NL7613187A (hu)
SE (1) SE421692B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284644A (en) * 1977-01-12 1981-08-18 Takeda Chemical Industries, Ltd. Spirobenzofuranone compounds
US4342779A (en) * 1977-12-27 1982-08-03 Takeda Chemical Industries, Ltd. 7-Acetylspirobenzofuranone compound
JPS5646879A (en) * 1979-09-25 1981-04-28 Takeda Chem Ind Ltd Spiro compound, its preparation, and preventive and remedy for circulatory system disorder
US4330554A (en) * 1980-04-23 1982-05-18 Takeda Chemical Industries, Ltd. Spirobenzofuranone compounds
FR2501676A1 (fr) * 1981-03-11 1982-09-17 Rhone Poulenc Spec Chim Procede de n-alkylation de composes organiques azotes
CA2589363A1 (en) * 2004-12-13 2006-06-22 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors

Also Published As

Publication number Publication date
SE421692B (sv) 1982-01-25
DE2653477A1 (de) 1977-06-08
NL7613187A (nl) 1977-05-31
BE848766A (fr) 1977-05-25
AU499472B2 (en) 1979-04-26
FR2362125A1 (fr) 1978-03-17
JPS5265267A (en) 1977-05-30
DK526476A (da) 1977-05-27
AU1997476A (en) 1978-06-01
CA1091656A (en) 1980-12-16
US4105670A (en) 1978-08-08
SE7613218L (sv) 1977-05-27
FR2362125B1 (hu) 1982-07-09
GB1570596A (en) 1980-07-02

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Legal Events

Date Code Title Description
PL Patent ceased