CH620452A5 - - Google Patents
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- Publication number
- CH620452A5 CH620452A5 CH726176A CH726176A CH620452A5 CH 620452 A5 CH620452 A5 CH 620452A5 CH 726176 A CH726176 A CH 726176A CH 726176 A CH726176 A CH 726176A CH 620452 A5 CH620452 A5 CH 620452A5
- Authority
- CH
- Switzerland
- Prior art keywords
- hydroxy
- methyl
- pregnan
- iodobenzoyl
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2526373A DE2526373C2 (de) | 1975-06-11 | 1975-06-11 | Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑-5α-20-Ketosteroiden |
Publications (1)
Publication Number | Publication Date |
---|---|
CH620452A5 true CH620452A5 (xx) | 1980-11-28 |
Family
ID=5948981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH726176A CH620452A5 (xx) | 1975-06-11 | 1976-06-09 |
Country Status (10)
Country | Link |
---|---|
US (1) | US4061661A (xx) |
JP (1) | JPS51149260A (xx) |
CH (1) | CH620452A5 (xx) |
DD (1) | DD125699A5 (xx) |
DE (1) | DE2526373C2 (xx) |
DK (1) | DK137837C (xx) |
FR (1) | FR2314197A1 (xx) |
GB (1) | GB1554901A (xx) |
HU (1) | HU174227B (xx) |
NL (1) | NL7606137A (xx) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2748442C3 (de) * | 1977-10-26 | 1981-08-27 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel |
US4252729A (en) * | 1978-05-12 | 1981-02-24 | Hoffmann-La Roche Inc. | Steroids and process for their manufacture |
US4252719A (en) * | 1978-08-17 | 1981-02-24 | Research Corporation | Steroid conversion method and products produced thereby |
DE2929558C2 (de) * | 1979-07-18 | 1982-03-11 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden |
US4328162A (en) * | 1980-09-05 | 1982-05-04 | Eastman Kodak Company | Process for preparing 9,11-unsaturated steroidal compound from the corresponding saturated steroidal compound |
US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
ES2738526T3 (es) | 2011-10-14 | 2020-01-23 | Sage Therapeutics Inc | Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos |
US20160068563A1 (en) | 2013-04-17 | 2016-03-10 | Boyd L. Harrison | 19-nor neuroactive steroids and methods of use thereof |
WO2014169831A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof |
SG11201508550XA (en) | 2013-04-17 | 2015-11-27 | Sage Therapeutics Inc | 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof |
CA2909546C (en) | 2013-04-17 | 2019-01-22 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
SI3021852T1 (sl) | 2013-07-19 | 2021-07-30 | Sage Therapeutics, Inc. | Nevroaktivni steroidi, sestavki in uporabe le-teh |
EP3035940B1 (en) | 2013-08-23 | 2018-10-17 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
PL3206493T3 (pl) | 2014-10-16 | 2021-01-25 | Sage Therapeutics, Inc. | Kompozycje i sposoby leczenia zaburzeń OUN |
SG10202009861SA (en) | 2014-10-16 | 2020-11-27 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
LT3224269T (lt) | 2014-11-27 | 2020-07-10 | Sage Therapeutics, Inc. | Kompozicijos ir būdai, skirti cns sutrikimams gydyti |
PL3250210T3 (pl) | 2015-01-26 | 2021-07-26 | Sage Therapeutics, Inc. | Kompozycje i sposoby leczenia zaburzeń OUN |
DK3258939T3 (da) | 2015-02-20 | 2022-12-12 | Sage Therapeutics Inc | Neuroaktive steroider, sammensætninger og anvendelser heraf |
WO2016164763A1 (en) * | 2015-04-10 | 2016-10-13 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
US20190233465A1 (en) | 2016-07-11 | 2019-08-01 | Sage Therapeutics, Inc. | C7, c12, and c16 substituted neuroactive steroids and their methods of use |
CN116162121A (zh) | 2016-07-11 | 2023-05-26 | 萨奇治疗股份有限公司 | C17、c20和c21取代的神经活性类固醇及其使用方法 |
EP3712161A1 (en) * | 2019-03-19 | 2020-09-23 | Bionice, S.L.U. | Process for preparing high puritiy allopregnanolone and intermediates thereof |
MX2021014515A (es) | 2019-05-31 | 2022-03-22 | Sage Therapeutics Inc | Esteroides neuroactivos y composiciones de estos. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2681353A (en) * | 1952-03-11 | 1954-06-15 | Sterling Drug Inc | Chlorination of keto-steroids |
GB1380248A (en) * | 1970-12-17 | 1975-01-08 | Glaxo Lab Ltd | 3alpha-hydroxy steroids and esters thereof |
-
1975
- 1975-06-11 DE DE2526373A patent/DE2526373C2/de not_active Expired
-
1976
- 1976-06-08 NL NL7606137A patent/NL7606137A/xx not_active Application Discontinuation
- 1976-06-08 US US05/693,848 patent/US4061661A/en not_active Expired - Lifetime
- 1976-06-09 JP JP51067563A patent/JPS51149260A/ja active Granted
- 1976-06-09 GB GB23849/76A patent/GB1554901A/en not_active Expired
- 1976-06-09 DD DD193275A patent/DD125699A5/xx unknown
- 1976-06-09 CH CH726176A patent/CH620452A5/de not_active IP Right Cessation
- 1976-06-10 HU HU76SCHE569A patent/HU174227B/hu not_active IP Right Cessation
- 1976-06-11 DK DK260976A patent/DK137837C/da not_active IP Right Cessation
- 1976-06-11 FR FR7617698A patent/FR2314197A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
NL7606137A (nl) | 1976-12-14 |
DK137837B (da) | 1978-05-16 |
FR2314197B1 (xx) | 1981-03-20 |
JPS51149260A (en) | 1976-12-22 |
DK260976A (da) | 1976-12-12 |
HU174227B (hu) | 1979-11-28 |
DD125699A5 (xx) | 1977-05-11 |
GB1554901A (en) | 1979-10-31 |
JPS6146480B2 (xx) | 1986-10-14 |
DE2526373C2 (de) | 1983-11-10 |
DE2526373A1 (de) | 1976-12-30 |
US4061661A (en) | 1977-12-06 |
DK137837C (da) | 1978-10-23 |
FR2314197A1 (fr) | 1977-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |