DK137837B - Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener - Google Patents

Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener

Info

Publication number
DK137837B
DK137837B DK260976AA DK260976A DK137837B DK 137837 B DK137837 B DK 137837B DK 260976A A DK260976A A DK 260976AA DK 260976 A DK260976 A DK 260976A DK 137837 B DK137837 B DK 137837B
Authority
DK
Denmark
Prior art keywords
5alfa
delta9
calculators
keto
preparing
Prior art date
Application number
DK260976AA
Other languages
English (en)
Other versions
DK260976A (da
DK137837C (da
Inventor
U Kerb
R Wiechert
O Engelfried
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK260976A publication Critical patent/DK260976A/da
Publication of DK137837B publication Critical patent/DK137837B/da
Application granted granted Critical
Publication of DK137837C publication Critical patent/DK137837C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK260976A 1975-06-11 1976-06-11 Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener DK137837C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2526373A DE2526373C2 (de) 1975-06-11 1975-06-11 Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑-5α-20-Ketosteroiden

Publications (3)

Publication Number Publication Date
DK260976A DK260976A (da) 1976-12-12
DK137837B true DK137837B (da) 1978-05-16
DK137837C DK137837C (da) 1978-10-23

Family

ID=5948981

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260976A DK137837C (da) 1975-06-11 1976-06-11 Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener

Country Status (10)

Country Link
US (1) US4061661A (da)
JP (1) JPS51149260A (da)
CH (1) CH620452A5 (da)
DD (1) DD125699A5 (da)
DE (1) DE2526373C2 (da)
DK (1) DK137837C (da)
FR (1) FR2314197A1 (da)
GB (1) GB1554901A (da)
HU (1) HU174227B (da)
NL (1) NL7606137A (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748442C3 (de) * 1977-10-26 1981-08-27 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel
US4252729A (en) * 1978-05-12 1981-02-24 Hoffmann-La Roche Inc. Steroids and process for their manufacture
US4252719A (en) * 1978-08-17 1981-02-24 Research Corporation Steroid conversion method and products produced thereby
DE2929558C2 (de) * 1979-07-18 1982-03-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden
US4328162A (en) * 1980-09-05 1982-05-04 Eastman Kodak Company Process for preparing 9,11-unsaturated steroidal compound from the corresponding saturated steroidal compound
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
CN108976272B (zh) 2011-10-14 2021-05-25 萨奇治疗股份有限公司 3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
ES2807264T3 (es) 2013-04-17 2021-02-22 Sage Therapeutics Inc Esteroides neuroactivos 19-nor para métodos de tratamiento
HUE041369T2 (hu) 2013-04-17 2019-05-28 Sage Therapeutics Inc 19-nor C3,3-diszubsztituált C21-N-pirazolil-szteroidok és eljárás ezek alkalmazására
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
CA3199003A1 (en) 2013-07-19 2015-01-22 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CA3235088A1 (en) 2013-08-23 2015-02-26 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MX2017005002A (es) 2014-10-16 2018-01-23 Sage Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos del snc.
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3719029A1 (en) 2014-11-27 2020-10-07 Sage Therapeutics, Inc. Compositions for inducing sedation
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
US20180311258A1 (en) * 2015-04-10 2018-11-01 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
IL309259A (en) 2016-07-11 2024-02-01 Sage Therapeutics Inc C17, C20 and C21 converted neuroactive steroids and methods of using them
JP7065825B2 (ja) 2016-07-11 2022-05-12 セージ セラピューティクス， インコーポレイテッド Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法
EP3712161A1 (en) * 2019-03-19 2020-09-23 Bionice, S.L.U. Process for preparing high puritiy allopregnanolone and intermediates thereof
MA56046A (fr) 2019-05-31 2022-04-06 Sage Therapeutics Inc Stéroïdes neuroactifs et compositions associées

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2681353A (en) * 1952-03-11 1954-06-15 Sterling Drug Inc Chlorination of keto-steroids
GB1380248A (en) * 1970-12-17 1975-01-08 Glaxo Lab Ltd 3alpha-hydroxy steroids and esters thereof

Also Published As

Publication number Publication date
HU174227B (hu) 1979-11-28
DE2526373A1 (de) 1976-12-30
JPS51149260A (en) 1976-12-22
JPS6146480B2 (da) 1986-10-14
DD125699A5 (da) 1977-05-11
DE2526373C2 (de) 1983-11-10
DK260976A (da) 1976-12-12
NL7606137A (nl) 1976-12-14
US4061661A (en) 1977-12-06
GB1554901A (en) 1979-10-31
DK137837C (da) 1978-10-23
FR2314197A1 (fr) 1977-01-07
FR2314197B1 (da) 1981-03-20
CH620452A5 (da) 1980-11-28

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