DK137837C - Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener - Google Patents

Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener

Info

Publication number
DK137837C
DK137837C DK260976A DK260976A DK137837C DK 137837 C DK137837 C DK 137837C DK 260976 A DK260976 A DK 260976A DK 260976 A DK260976 A DK 260976A DK 137837 C DK137837 C DK 137837C
Authority
DK
Denmark
Prior art keywords
5alfa
delta9
calculators
keto
preparing
Prior art date
Application number
DK260976A
Other languages
English (en)
Other versions
DK260976A (da
DK137837B (da
Inventor
U Kerb
R Wiechert
O Engelfried
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK260976A publication Critical patent/DK260976A/da
Publication of DK137837B publication Critical patent/DK137837B/da
Application granted granted Critical
Publication of DK137837C publication Critical patent/DK137837C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK260976A 1975-06-11 1976-06-11 Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener DK137837C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2526373A DE2526373C2 (de) 1975-06-11 1975-06-11 Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑-5α-20-Ketosteroiden

Publications (3)

Publication Number Publication Date
DK260976A DK260976A (da) 1976-12-12
DK137837B DK137837B (da) 1978-05-16
DK137837C true DK137837C (da) 1978-10-23

Family

ID=5948981

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260976A DK137837C (da) 1975-06-11 1976-06-11 Fremgangsmaade til fremstilling af delta9(11)-5alfa-20-ketopregnener

Country Status (10)

Country Link
US (1) US4061661A (da)
JP (1) JPS51149260A (da)
CH (1) CH620452A5 (da)
DD (1) DD125699A5 (da)
DE (1) DE2526373C2 (da)
DK (1) DK137837C (da)
FR (1) FR2314197A1 (da)
GB (1) GB1554901A (da)
HU (1) HU174227B (da)
NL (1) NL7606137A (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748442C3 (de) * 1977-10-26 1981-08-27 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel
US4252729A (en) * 1978-05-12 1981-02-24 Hoffmann-La Roche Inc. Steroids and process for their manufacture
US4252719A (en) * 1978-08-17 1981-02-24 Research Corporation Steroid conversion method and products produced thereby
DE2929558C2 (de) * 1979-07-18 1982-03-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden
US4328162A (en) * 1980-09-05 1982-05-04 Eastman Kodak Company Process for preparing 9,11-unsaturated steroidal compound from the corresponding saturated steroidal compound
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
CA3152410A1 (en) 2011-10-14 2013-04-18 Sage Therapeutics, Inc. 3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
CN112110976B (zh) 2013-04-17 2023-08-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
CN113527400A (zh) 2013-04-17 2021-10-22 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
LT3021852T (lt) 2013-07-19 2021-04-12 Sage Therapeutics, Inc. Neuroaktyvūs steroidai, jų kompozicijos ir panaudojimas
DK3488852T3 (da) 2013-08-23 2021-02-01 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser deraf
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
ES2808855T3 (es) 2014-10-16 2021-03-02 Sage Therapeutics Inc Composiciones y métodos para tratar trastornos del SNC
TW202235090A (zh) 2014-10-16 2022-09-16 美商賽吉醫療公司 用於治療中樞神經系統(cns)病症之組合物及方法
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
HUE054092T2 (hu) 2015-01-26 2021-08-30 Sage Therapeutics Inc Központi idegrendszeri zavarok kezelésére szolgáló kompozíciók és eljárások
ES2935476T3 (es) 2015-02-20 2023-03-07 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
EP3280420B1 (en) * 2015-04-10 2024-03-27 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
CA3030420A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C20, C17 and C21 converted neuroactive steroids and methods of using them
EP3712161A1 (en) * 2019-03-19 2020-09-23 Bionice, S.L.U. Process for preparing high puritiy allopregnanolone and intermediates thereof
BR112021024033A2 (pt) 2019-05-31 2022-02-08 Sage Therapeutics Inc Esteroides neuroativos e suas composições

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2681353A (en) * 1952-03-11 1954-06-15 Sterling Drug Inc Chlorination of keto-steroids
GB1380248A (en) * 1970-12-17 1975-01-08 Glaxo Lab Ltd 3alpha-hydroxy steroids and esters thereof

Also Published As

Publication number Publication date
HU174227B (hu) 1979-11-28
JPS51149260A (en) 1976-12-22
DK260976A (da) 1976-12-12
NL7606137A (nl) 1976-12-14
CH620452A5 (da) 1980-11-28
DE2526373C2 (de) 1983-11-10
DK137837B (da) 1978-05-16
US4061661A (en) 1977-12-06
FR2314197B1 (da) 1981-03-20
JPS6146480B2 (da) 1986-10-14
GB1554901A (en) 1979-10-31
FR2314197A1 (fr) 1977-01-07
DE2526373A1 (de) 1976-12-30
DD125699A5 (da) 1977-05-11

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