CH619967A5 - Process for the preparation of nitrosourea derivatives - Google Patents

Process for the preparation of nitrosourea derivatives Download PDF

Info

Publication number
CH619967A5
CH619967A5 CH1033175A CH1033175A CH619967A5 CH 619967 A5 CH619967 A5 CH 619967A5 CH 1033175 A CH1033175 A CH 1033175A CH 1033175 A CH1033175 A CH 1033175A CH 619967 A5 CH619967 A5 CH 619967A5
Authority
CH
Switzerland
Prior art keywords
group
formula
nitrosourea
methyl
carbon atoms
Prior art date
Application number
CH1033175A
Other languages
German (de)
English (en)
Inventor
Tetsuo Suami
Tomoya Machinami
Takashi Hisamatsu
Original Assignee
Suami T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP49090266A external-priority patent/JPS5126876A/ja
Priority claimed from JP12431974A external-priority patent/JPS5152128A/ja
Priority claimed from JP3113175A external-priority patent/JPS51108043A/ja
Application filed by Suami T filed Critical Suami T
Publication of CH619967A5 publication Critical patent/CH619967A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68—N-nitroso ureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH1033175A 1974-08-08 1975-08-07 Process for the preparation of nitrosourea derivatives CH619967A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP49090266A JPS5126876A (en) 1974-08-08 1974-08-08 Shinkina nitorosonyosojudotaino seizohoho
JP12431974A JPS5152128A (ja) 1974-10-30 1974-10-30 Nitorosonyosojudotaino shinseizoho
JP3113175A JPS51108043A (ja) 1975-03-17 1975-03-17 Nitorosonyosokagobutsunoseiho

Publications (1)

Publication Number Publication Date
CH619967A5 true CH619967A5 (en) 1980-10-31

Family

ID=27287217

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1033175A CH619967A5 (en) 1974-08-08 1975-08-07 Process for the preparation of nitrosourea derivatives

Country Status (11)

Country Link
AT (1) AT351555B (sv)
CH (1) CH619967A5 (sv)
DE (1) DE2535048C3 (sv)
ES (1) ES440147A1 (sv)
FR (1) FR2281102A1 (sv)
GB (1) GB1507099A (sv)
HU (1) HU175174B (sv)
IL (1) IL47842A (sv)
NL (1) NL7509445A (sv)
SE (1) SE430340B (sv)
YU (1) YU39743B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5331664A (en) * 1976-09-02 1978-03-25 Suami T Production of novel nitroso urea derivatives
US4182757A (en) * 1977-07-29 1980-01-08 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
JPS5940400B2 (ja) * 1980-03-24 1984-09-29 わかもと製薬株式会社 新規ｄ−アロ−ス誘導体及びこれを有効成分とする抗腫瘍剤
DE3323095A1 (de) * 1983-06-27 1985-01-03 Institut organičeskoj chimii Akademii Nauk Kirgizskoj SSR, Frunze Verfahren zur herstellung von n-alkyl-n'-glykosyl-n-nitrosourethan
CA2357977A1 (en) * 1998-12-29 2000-07-06 Donald R. Kahn Method for prevention or treatment of acute allograft rejection and a pharmaceutical composition therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518270A (de) * 1969-03-07 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von Nitrosoharnstoffverbindungen
JPS4843333B1 (sv) * 1970-04-25 1973-12-18

Also Published As

Publication number Publication date
FR2281102B1 (sv) 1979-04-06
DE2535048B2 (de) 1979-06-07
HU175174B (hu) 1980-05-28
ATA618475A (de) 1979-01-15
YU39743B (en) 1985-04-30
DE2535048C3 (de) 1980-02-14
GB1507099A (en) 1978-04-12
IL47842A0 (en) 1975-10-15
ES440147A1 (es) 1977-06-16
AU8380475A (en) 1977-02-10
SE7508840L (sv) 1976-02-09
SE430340B (sv) 1983-11-07
YU203475A (en) 1982-02-28
AT351555B (de) 1979-08-10
FR2281102A1 (fr) 1976-03-05
DE2535048A1 (de) 1976-02-19
IL47842A (en) 1980-07-31
NL7509445A (nl) 1976-02-10

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PL Patent ceased