CH616678A5 - - Google Patents

Download PDF

Info

Publication number
CH616678A5
CH616678A5 CH132675A CH132675A CH616678A5 CH 616678 A5 CH616678 A5 CH 616678A5 CH 132675 A CH132675 A CH 132675A CH 132675 A CH132675 A CH 132675A CH 616678 A5 CH616678 A5 CH 616678A5
Authority
CH
Switzerland
Prior art keywords
dopamine
parkinson
piperazine
general formula
brain
Prior art date
Application number
CH132675A
Other languages
German (de)
English (en)
Inventor
Harlan Ford Hill
John Joseph Lafferty
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of CH616678A5 publication Critical patent/CH616678A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CH132675A 1974-02-07 1975-02-04 CH616678A5 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US440431A US3919230A (en) 1974-02-07 1974-02-07 {62 -Naphthylmethyl piperazinyl derivatives

Publications (1)

Publication Number Publication Date
CH616678A5 true CH616678A5 (hu) 1980-04-15

Family

ID=23748733

Family Applications (1)

Application Number Title Priority Date Filing Date
CH132675A CH616678A5 (hu) 1974-02-07 1975-02-04

Country Status (16)

Country Link
US (1) US3919230A (hu)
JP (1) JPS50108278A (hu)
AU (1) AU501049B2 (hu)
BE (1) BE825178A (hu)
CA (1) CA1042434A (hu)
CH (1) CH616678A5 (hu)
DE (1) DE2505002A1 (hu)
ES (1) ES434433A1 (hu)
FR (1) FR2260353B1 (hu)
GB (1) GB1449802A (hu)
HU (1) HU171352B (hu)
IE (1) IE40593B1 (hu)
IL (1) IL46568A (hu)
LU (1) LU71803A1 (hu)
NL (1) NL7501362A (hu)
ZA (1) ZA75160B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US6335343B1 (en) 1999-03-03 2002-01-01 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CN107652156B (zh) * 2017-11-18 2023-11-10 辽宁科技学院 一种β-甲基萘的结晶方法和装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127996C (hu) * 1963-11-19

Also Published As

Publication number Publication date
LU71803A1 (hu) 1975-06-24
IE40593B1 (en) 1979-07-04
IE40593L (en) 1975-08-07
NL7501362A (nl) 1975-08-11
AU501049B2 (en) 1979-06-07
BE825178A (fr) 1975-08-04
ES434433A1 (es) 1976-11-16
IL46568A (en) 1979-01-31
IL46568A0 (en) 1975-04-25
US3919230A (en) 1975-11-11
DE2505002A1 (de) 1975-08-14
CA1042434A (en) 1978-11-14
AU7784075A (en) 1976-08-05
GB1449802A (en) 1976-09-15
FR2260353A1 (hu) 1975-09-05
JPS50108278A (hu) 1975-08-26
FR2260353B1 (hu) 1980-01-04
ZA75160B (en) 1976-01-28
HU171352B (hu) 1977-12-28

Similar Documents

Publication Publication Date Title
AT390257B (de) Verfahren zur herstellung neuer imidazo(4,5-b)chinolin-derivate
DE2559755A1 (de) Substituierte oxazolidine
DE1470157A1 (de) Verfahren zur Herstellung substituierter Thioxanthensulfonamide und ihrer Saeureanlagerungssalze
DE2238504B2 (de) l-Phenoxy-3-alkylaminopropan-2-ol -Derivate
CH649287A5 (de) Carboximid-derivate, verfahren zur herstellung derselben sowie solche carboximid-derivate enthaltende medikamente.
DE60004671T2 (de) Neue piperazinylalkylthiopyrimidine derivate, diese enthaltende pharmazeutische zusammenstellungen und verfahren zu deren herstellung
DE3334757A1 (de) Piperazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
DE2426149C3 (de) 7-Fluor-substituierte Phenothiazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
CH616678A5 (hu)
DD272080A5 (de) Verfahren zur herstellung von arylpiperazinyl-alkylenphenyl-heterocyclische-verbindungen
EP0155903B1 (de) Indolophenanthridine, ihre Herstellung und Verwendung
DE2642331A1 (de) Basisch substituierte pyridincarboxamide
CH616141A5 (hu)
DE3538063C2 (hu)
DE1965888A1 (de) Anilinderivate
DE2745742A1 (de) Piperidylidenderivate von benzoxanthenen, -thioxanthenen und -dibenzoxepinen, verfahren zu deren herstellung und deren verwendung als psychopharmaca
CH637391A5 (de) Therapeutisch wirksame 3-(1-piperazinyl)-1,2,4-benzotriazine und ihre n-oxide.
EP0088323B1 (de) Imidazothiadiazolalkencarbonsäureamide, neue Zwischenprodukte zu ihrer Herstellung, ihre Herstellung und ihre Verwendung in Arzneimitteln
DE2359359A1 (de) Fluor-substituierte thioxanthene und verfahren zu deren herstellung sowie diese enthaltende pharmazeutische mittel
DE2456098B2 (de) Xanthen- und Thioxanthen-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1445636A1 (de) Alkylenimine
DE2322350A1 (de) 1,8-naphthyridin-2(1h)-on-derivate und verfahren zu ihrer herstellung
DE2814798C2 (hu)
DE1936670C3 (de) S-Diallylaminoalkanoyl-SJO-dihydro-11H-dibenzo eckige Klammer auf b,e eckige Klammer zu- eckige Klammer auf 1,4 eckige Klammer zu diazepin-11-onderivate
DE2057048A1 (de) Neue Amine und Verfahren zu ihrer Herstellung

Legal Events

Date Code Title Description
PL Patent ceased