GB1449802A - Piperazine derivatives and compositions containing them for treating parkinsons disease - Google Patents

Piperazine derivatives and compositions containing them for treating parkinsons disease

Info

Publication number
GB1449802A
GB1449802A GB453675A GB453675A GB1449802A GB 1449802 A GB1449802 A GB 1449802A GB 453675 A GB453675 A GB 453675A GB 453675 A GB453675 A GB 453675A GB 1449802 A GB1449802 A GB 1449802A
Authority
GB
United Kingdom
Prior art keywords
piperazine
naphthylmethyl
substituted
chloromethylnaphthalene
piperazines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB453675A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of GB1449802A publication Critical patent/GB1449802A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
GB453675A 1974-02-07 1975-02-03 Piperazine derivatives and compositions containing them for treating parkinsons disease Expired GB1449802A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US440431A US3919230A (en) 1974-02-07 1974-02-07 {62 -Naphthylmethyl piperazinyl derivatives

Publications (1)

Publication Number Publication Date
GB1449802A true GB1449802A (en) 1976-09-15

Family

ID=23748733

Family Applications (1)

Application Number Title Priority Date Filing Date
GB453675A Expired GB1449802A (en) 1974-02-07 1975-02-03 Piperazine derivatives and compositions containing them for treating parkinsons disease

Country Status (16)

Country Link
US (1) US3919230A (hu)
JP (1) JPS50108278A (hu)
AU (1) AU501049B2 (hu)
BE (1) BE825178A (hu)
CA (1) CA1042434A (hu)
CH (1) CH616678A5 (hu)
DE (1) DE2505002A1 (hu)
ES (1) ES434433A1 (hu)
FR (1) FR2260353B1 (hu)
GB (1) GB1449802A (hu)
HU (1) HU171352B (hu)
IE (1) IE40593B1 (hu)
IL (1) IL46568A (hu)
LU (1) LU71803A1 (hu)
NL (1) NL7501362A (hu)
ZA (1) ZA75160B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US6335343B1 (en) 1999-03-03 2002-01-01 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
CN107652156B (zh) * 2017-11-18 2023-11-10 辽宁科技学院 一种β-甲基萘的结晶方法和装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL127996C (hu) * 1963-11-19

Also Published As

Publication number Publication date
LU71803A1 (hu) 1975-06-24
IE40593B1 (en) 1979-07-04
IE40593L (en) 1975-08-07
NL7501362A (nl) 1975-08-11
AU501049B2 (en) 1979-06-07
CH616678A5 (hu) 1980-04-15
BE825178A (fr) 1975-08-04
ES434433A1 (es) 1976-11-16
IL46568A (en) 1979-01-31
IL46568A0 (en) 1975-04-25
US3919230A (en) 1975-11-11
DE2505002A1 (de) 1975-08-14
CA1042434A (en) 1978-11-14
AU7784075A (en) 1976-08-05
FR2260353A1 (hu) 1975-09-05
JPS50108278A (hu) 1975-08-26
FR2260353B1 (hu) 1980-01-04
ZA75160B (en) 1976-01-28
HU171352B (hu) 1977-12-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee