CH615947A5 - Process for the cultivation of anchorage-dependent cells in a microcarrier culture, microcarriers for carrying it out and use of the process. - Google Patents

Process for the cultivation of anchorage-dependent cells in a microcarrier culture, microcarriers for carrying it out and use of the process. Download PDF

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Publication number
CH615947A5
CH615947A5 CH1382677A CH1382677A CH615947A5 CH 615947 A5 CH615947 A5 CH 615947A5 CH 1382677 A CH1382677 A CH 1382677A CH 1382677 A CH1382677 A CH 1382677A CH 615947 A5 CH615947 A5 CH 615947A5
Authority
CH
Switzerland
Prior art keywords
microcarrier
microcarriers
cells
groups
beads
Prior art date
Application number
CH1382677A
Other languages
German (de)
English (en)
Inventor
David W Levine
William G Thilly
Daniel I C Wang
Jason S Wong
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of CH615947A5 publication Critical patent/CH615947A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CH1382677A 1976-11-11 1977-11-11 Process for the cultivation of anchorage-dependent cells in a microcarrier culture, microcarriers for carrying it out and use of the process. CH615947A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74099376A 1976-11-11 1976-11-11

Publications (1)

Publication Number Publication Date
CH615947A5 true CH615947A5 (en) 1980-02-29

Family

ID=24978920

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1382677A CH615947A5 (en) 1976-11-11 1977-11-11 Process for the cultivation of anchorage-dependent cells in a microcarrier culture, microcarriers for carrying it out and use of the process.

Country Status (14)

Country Link
JP (3) JPS5362889A (nl)
AU (1) AU508398B2 (nl)
BE (1) BE860721A (nl)
BR (1) BR7707551A (nl)
CA (1) CA1063050A (nl)
CH (1) CH615947A5 (nl)
DE (2) DE2749989C3 (nl)
FI (1) FI60407C (nl)
FR (1) FR2370792A1 (nl)
GB (1) GB1535150A (nl)
IN (1) IN147612B (nl)
NL (1) NL177926C (nl)
SE (2) SE417108C (nl)
ZA (1) ZA776251B (nl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA776251B (en) * 1976-11-11 1978-07-26 Massachusetts Inst Technology Improved cell culture microcarriers
FR2470794A1 (fr) * 1979-12-05 1981-06-12 Pasteur Institut Nouvelles microparticules, leur preparation et leurs applications en biologie, notamment a la culture de cellules diploides humaines
US4448884A (en) * 1982-03-03 1984-05-15 Kms Fusion, Inc. Glass-surface microcarrier for growth of cell cultures
JPS592735U (ja) * 1982-06-28 1984-01-09 シャープ株式会社 給紙用カセツト内の用紙残量指示装置
JPS60126453U (ja) * 1984-02-02 1985-08-26 富士ゼロックス株式会社 フアクシミリ等の用紙残量表示装置
IL74259A0 (en) * 1984-02-06 1985-05-31 Surface Concepts Pty Ltd Improved method for cell culture
JPS60145139U (ja) * 1984-03-07 1985-09-26 日本電信電話株式会社 シ−ト状記録紙の残量表示装置
SE454518B (sv) * 1984-05-21 1988-05-09 Statens Bakteriologiska Lab Forfarande for odling av diploida celler i nervaro av cellulosafibrer
JP2606213B2 (ja) * 1986-04-22 1997-04-30 味の素株式会社 修飾された微生物産生セルロースのゲルおよび動物細胞膜との複合体
DE3633891A1 (de) * 1986-10-04 1988-04-07 Akzo Gmbh Verfahren und vorrichtung zum kultivieren von tierischen zellen
US20140170748A1 (en) * 2012-12-14 2014-06-19 DePuy Synthes Products, LLC Nutrient Enriched Media for hUTC Growth
CN113249311B (zh) * 2020-05-25 2022-06-28 北京唐颐惠康生物医学技术有限公司 间充质干细胞培养用可降解微载体的制备方法及其产品和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436323A (en) * 1972-04-26 1976-05-19 Wellcome Found Cell and virus culture systems
US3901095A (en) * 1974-06-17 1975-08-26 Joseph W Wechsler Bicycle gear shift
US3935067A (en) * 1974-11-22 1976-01-27 Wyo-Ben Products, Inc. Inorganic support for culture media
ZA776251B (en) * 1976-11-11 1978-07-26 Massachusetts Inst Technology Improved cell culture microcarriers
JPS5614270A (en) * 1979-07-14 1981-02-12 Ricoh Co Ltd Wet type development after treating device

Also Published As

Publication number Publication date
SE417108C (sv) 1989-04-17
BR7707551A (pt) 1978-06-20
NL177926B (nl) 1985-07-16
DE2749989A1 (de) 1978-05-18
AU508398B2 (en) 1980-03-20
DE2749989B2 (de) 1979-10-25
NL7712202A (nl) 1978-05-16
IN147612B (nl) 1980-05-03
ZA776251B (en) 1978-07-26
JPS5362889A (en) 1978-06-05
FI60407C (fi) 1982-01-11
AU3049177A (en) 1979-06-28
FI60407B (fi) 1981-09-30
FR2370792B1 (nl) 1983-07-29
JPS5699789A (en) 1981-08-11
SE7712700L (sv) 1978-05-12
CA1063050A (en) 1979-09-25
DE2749989C3 (de) 1980-07-03
BE860721A (nl) 1978-03-01
GB1535150A (en) 1978-12-06
JPS575514B2 (nl) 1982-01-30
DE2759579C2 (de) 1983-08-25
JPS5614270B2 (nl) 1981-04-03
NL177926C (nl) 1985-12-16
SE8006993L (sv) 1980-10-07
FI773377A (fi) 1978-05-12
JPS5735953B2 (nl) 1982-07-31
JPS5699790A (en) 1981-08-11
SE417108B (sv) 1981-02-23
FR2370792A1 (fr) 1978-06-09
SE460906B (sv) 1989-12-04

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PL Patent ceased