CH612425A5 - Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans - Google Patents

Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans

Info

Publication number
CH612425A5
CH612425A5 CH280275A CH280275A CH612425A5 CH 612425 A5 CH612425 A5 CH 612425A5 CH 280275 A CH280275 A CH 280275A CH 280275 A CH280275 A CH 280275A CH 612425 A5 CH612425 A5 CH 612425A5
Authority
CH
Switzerland
Prior art keywords
benzomorphans
tetrahydrofurfuryl
novel
preparation
Prior art date
Application number
CH280275A
Other languages
English (en)
Inventor
Herbert Dr Merz
Adolf Dr Langbein
Gerhard Dr Walther
Klaus Dr Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of CH612425A5 publication Critical patent/CH612425A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH280275A 1974-03-09 1975-03-05 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans CH612425A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
CH612425A5 true CH612425A5 (en) 1979-07-31

Family

ID=5909593

Family Applications (8)

Application Number Title Priority Date Filing Date
CH280275A CH612425A5 (en) 1974-03-09 1975-03-05 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384579A CH622015A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384479A CH622014A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384979A CH622017A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384779A CH622016A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384879A CH620681A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384679A CH620440A5 (en) 1974-03-09 1979-04-24 Process for the preparation of 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384379A CH620439A5 (en) 1974-03-09 1979-04-24 Process for the preparation of 2-tetrahydrofurfuryl- 6,7-benzomorphans

Family Applications After (7)

Application Number Title Priority Date Filing Date
CH384579A CH622015A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384479A CH622014A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384979A CH622017A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384779A CH622016A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384879A CH620681A5 (en) 1974-03-09 1979-04-24 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384679A CH620440A5 (en) 1974-03-09 1979-04-24 Process for the preparation of 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384379A CH620439A5 (en) 1974-03-09 1979-04-24 Process for the preparation of 2-tetrahydrofurfuryl- 6,7-benzomorphans

Country Status (25)

Country Link
JP (1) JPS5827275B2 (en, 2012)
AT (1) AT344332B (en, 2012)
BE (1) BE826440A (en, 2012)
BG (3) BG24814A4 (en, 2012)
CA (1) CA1049511A (en, 2012)
CH (8) CH612425A5 (en, 2012)
CS (1) CS188221B2 (en, 2012)
DD (1) DD119236A5 (en, 2012)
DE (1) DE2411382C3 (en, 2012)
DK (1) DK137188C (en, 2012)
ES (6) ES440348A1 (en, 2012)
FI (1) FI63571C (en, 2012)
FR (1) FR2262984B1 (en, 2012)
GB (1) GB1496418A (en, 2012)
HU (1) HU177408B (en, 2012)
IE (1) IE40945B1 (en, 2012)
IL (1) IL46760A (en, 2012)
NL (1) NL7502724A (en, 2012)
NO (1) NO141800C (en, 2012)
PH (1) PH14127A (en, 2012)
PL (3) PL93499B1 (en, 2012)
RO (2) RO70051A (en, 2012)
SE (1) SE421919B (en, 2012)
SU (3) SU577982A3 (en, 2012)
ZA (1) ZA751394B (en, 2012)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
KR100444007B1 (ko) * 1995-03-10 2004-12-03 포토큐레 에이에스에이 광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
TW200911796A (en) 2007-07-26 2009-03-16 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2220048B1 (en) 2007-11-16 2017-01-25 Boehringer Ingelheim International GmbH Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001059A1 (es) 2008-05-01 2010-11-12 Boehringer Ingelheim Int Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras.
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5711115B2 (ja) 2008-05-13 2015-04-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリサイクリックカルボン酸誘導体、そのような化合物を含有する医薬及びその使用
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
ES2432150T3 (es) 2008-07-25 2013-12-02 Boehringer Ingelheim International Gmbh Inhibidores cíclicos de la 11 beta-hidroxiesteroide deshidrogenasa 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
DK137188B (da) 1978-01-30
BE826440A (fr) 1975-09-08
IE40945L (en) 1975-09-09
FI63571B (fi) 1983-03-31
IL46760A (en) 1978-12-17
CH620681A5 (en) 1980-12-15
HU177408B (en) 1981-10-28
CH622015A5 (en) 1981-03-13
CH620439A5 (en) 1980-11-28
ZA751394B (en) 1976-11-24
DE2411382C3 (de) 1979-09-06
AU7894275A (en) 1976-09-16
DD119236A5 (en, 2012) 1976-04-12
ES440347A1 (es) 1977-06-01
NL7502724A (nl) 1975-09-11
ES440349A1 (es) 1977-03-01
NO750773L (en, 2012) 1975-09-10
GB1496418A (en) 1977-12-30
SE7502592L (en, 2012) 1975-09-10
IE40945B1 (en) 1979-09-12
NO141800B (no) 1980-02-04
PL93700B1 (en, 2012) 1977-06-30
DE2411382B2 (de) 1979-01-18
SU588916A3 (ru) 1978-01-15
FR2262984B1 (en, 2012) 1978-07-28
PH14127A (en) 1981-02-26
PL93499B1 (en, 2012) 1977-05-30
DK92975A (en, 2012) 1975-09-10
FI63571C (fi) 1983-07-11
CH620440A5 (en) 1980-11-28
BG24813A4 (bg) 1978-05-12
RO70051A (ro) 1980-12-30
SE421919B (sv) 1982-02-08
CH622014A5 (en) 1981-03-13
SU577982A3 (ru) 1977-10-25
ES440346A1 (es) 1977-03-01
RO69617A (ro) 1980-08-15
CA1049511A (en) 1979-02-27
NO141800C (no) 1980-06-04
DE2411382A1 (de) 1975-09-18
ATA153875A (de) 1977-11-15
ES440348A1 (es) 1977-06-01
DK137188C (da) 1978-07-03
CH622017A5 (en) 1981-03-13
SU577983A3 (ru) 1977-10-25
JPS5827275B2 (ja) 1983-06-08
BG24814A4 (bg) 1978-05-12
JPS50123675A (en, 2012) 1975-09-29
ES440350A1 (es) 1977-03-16
FI750652A7 (en, 2012) 1975-09-10
BG25087A3 (bg) 1978-07-12
CS188221B2 (en) 1979-02-28
ES440345A1 (es) 1977-03-01
CH622016A5 (en) 1981-03-13
FR2262984A1 (en, 2012) 1975-10-03
AT344332B (de) 1978-07-10
PL93699B1 (en, 2012) 1977-06-30
IL46760A0 (en) 1975-05-22

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