CH609342A5 - - Google Patents
Info
- Publication number
- CH609342A5 CH609342A5 CH218575A CH218575A CH609342A5 CH 609342 A5 CH609342 A5 CH 609342A5 CH 218575 A CH218575 A CH 218575A CH 218575 A CH218575 A CH 218575A CH 609342 A5 CH609342 A5 CH 609342A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2408804A DE2408804C2 (de) | 1974-02-23 | 1974-02-23 | 1-(2-Methoxyphenyl)-4-[3-(naphth-1-yl-oxy)-2-hydroxy-propyl]-piperazin, dessen Salze, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH609342A5 true CH609342A5 (forum.php) | 1979-02-28 |
Family
ID=5908286
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1023478A CH612958A5 (forum.php) | 1974-02-23 | 1975-02-21 | |
| CH218575A CH609342A5 (forum.php) | 1974-02-23 | 1975-02-21 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1023478A CH612958A5 (forum.php) | 1974-02-23 | 1975-02-21 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3997666A (forum.php) |
| JP (1) | JPS6029712B2 (forum.php) |
| AR (1) | AR206339A1 (forum.php) |
| AT (1) | AT340937B (forum.php) |
| BE (1) | BE825755A (forum.php) |
| CA (1) | CA1039282A (forum.php) |
| CH (2) | CH612958A5 (forum.php) |
| DE (1) | DE2408804C2 (forum.php) |
| DK (1) | DK135124C (forum.php) |
| ES (1) | ES434829A1 (forum.php) |
| FI (1) | FI59248C (forum.php) |
| FR (1) | FR2261770B1 (forum.php) |
| GB (1) | GB1445548A (forum.php) |
| IE (1) | IE40678B1 (forum.php) |
| NL (2) | NL175059B (forum.php) |
| PL (1) | PL92131B1 (forum.php) |
| SE (1) | SE405601B (forum.php) |
| SU (2) | SU549085A3 (forum.php) |
| YU (2) | YU37156B (forum.php) |
| ZA (1) | ZA751031B (forum.php) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2387971A1 (fr) * | 1977-04-19 | 1978-11-17 | Delalande Sa | Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique |
| EP0269383A3 (en) * | 1986-11-21 | 1990-05-02 | A.H. Robins Company, Incorporated | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents |
| US4882330A (en) * | 1986-11-21 | 1989-11-21 | A. H. Robins Company, Incorporated | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents |
| DE3918542A1 (de) * | 1989-06-07 | 1990-12-13 | Boehringer Mannheim Gmbh | Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE3918543A1 (de) * | 1989-06-07 | 1990-12-13 | Boehringer Mannheim Gmbh | Verwendung von naftopidil zur therapie der dysurie bei benigner prostata-hypertrophie |
| US5932538A (en) * | 1996-02-02 | 1999-08-03 | Nitromed, Inc. | Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses |
| US20020143007A1 (en) * | 1996-02-02 | 2002-10-03 | Garvey David S. | Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use |
| US20050065161A1 (en) * | 1996-02-02 | 2005-03-24 | Nitromed, Inc. | Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
| KR20000070507A (ko) | 1997-01-30 | 2000-11-25 | 요시다 쇼지 | 하이드로퀴논 유도체 |
| EP1891954A3 (en) | 1998-09-30 | 2009-01-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder |
| US20020065286A1 (en) * | 2000-08-21 | 2002-05-30 | Davies Michael John | Treatment of wounds |
| US20020091129A1 (en) * | 2000-11-20 | 2002-07-11 | Mitradev Boolell | Treatment of premature ejaculation |
| US20030229001A1 (en) * | 2002-01-31 | 2003-12-11 | Pfizer Inc. | Treatment of male sexual dysfunction |
| AU2003250483A1 (en) | 2002-08-19 | 2004-03-11 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
| GB0219961D0 (en) | 2002-08-28 | 2002-10-02 | Pfizer Ltd | Oxytocin inhibitors |
| US7323462B2 (en) * | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
| MXPA05006333A (es) | 2002-12-13 | 2005-08-26 | Warner Lambert Co | Metodo de tratamiento. |
| CA2451267A1 (en) * | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
| PA8597401A1 (es) * | 2003-03-14 | 2005-05-24 | Pfizer | Derivados del acido 3-(1-[3-(1,3-benzotiazol-6-il) propilcarbamoil] cicloalquil) propanoico como inhibidores de nep |
| US20040220186A1 (en) * | 2003-04-30 | 2004-11-04 | Pfizer Inc. | PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease |
| KR20110117731A (ko) | 2003-05-30 | 2011-10-27 | 랜박시 래보러터리스 리미티드 | 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도 |
| US20050065158A1 (en) * | 2003-07-16 | 2005-03-24 | Pfizer Inc. | Treatment of sexual dysfunction |
| US7291640B2 (en) * | 2003-09-22 | 2007-11-06 | Pfizer Inc. | Substituted triazole derivatives as oxytocin antagonists |
| DE602006003416D1 (de) | 2005-03-21 | 2008-12-11 | Pfizer Ltd | Substituierte triazolderivate als oxytocinantagonisten |
| CA2618103A1 (en) * | 2005-08-10 | 2007-02-15 | Pfizer Limited | Substituted triazole derivatives as oxytocin antagonists |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| SG166829A1 (en) | 2005-11-08 | 2010-12-29 | Ranbaxy Lab Ltd | Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| EP2077262A4 (en) | 2006-10-23 | 2011-12-28 | Takeda Pharmaceutical | IMINOPYRIDINE DERIVATIVE AND USE THEREOF |
| JP5498168B2 (ja) | 2006-12-01 | 2014-05-21 | ブリストル−マイヤーズ スクイブ カンパニー | アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体 |
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| US20110039892A1 (en) | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| CN101671317B (zh) * | 2009-10-09 | 2011-04-27 | 蚌埠丰原涂山制药有限公司 | 一种萘哌地尔的制备方法 |
| CN101747293B (zh) * | 2009-12-29 | 2011-12-07 | 蚌埠丰原涂山制药有限公司 | 萘哌地尔的制备方法 |
| JP5807423B2 (ja) * | 2011-07-21 | 2015-11-10 | 大日本印刷株式会社 | ナフトピジルの製造方法 |
| CN102816136A (zh) * | 2012-09-18 | 2012-12-12 | 通化吉通药业有限公司 | 萘哌地尔制备方法 |
| BR112015026513A2 (pt) | 2013-04-17 | 2017-07-25 | Pfizer | derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares |
| US9272980B2 (en) | 2014-06-06 | 2016-03-01 | Ktn Biotec, Inc. | Anticancer agent |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| FI3911648T3 (fi) | 2019-01-18 | 2025-01-10 | Astrazeneca Ab | 6'-[[[(1s,3s)-3-[[5-(difluorometoksi)-2-pyrimidinyyli]amino]syklopentyyli]amino][1(2h),3'-bipyridin]-2-oni pcsk9:n estäjänä ja menetelmät sen käyttöön |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA967965A (en) * | 1968-12-24 | 1975-05-20 | Hoffmann-La Roche Limited | Aromatic ethers and process for the manufacture thereof |
| GB1317479A (en) * | 1970-11-10 | 1973-05-16 | Pfizer Ltd | 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives |
| DE2235597A1 (de) * | 1972-07-20 | 1974-01-31 | Boehringer Mannheim Gmbh | 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung |
-
0
- NL NLAANVRAGE7501877,A patent/NL175059C/xx active
-
1974
- 1974-02-23 DE DE2408804A patent/DE2408804C2/de not_active Expired
-
1975
- 1975-01-01 AR AR257639A patent/AR206339A1/es active
- 1975-01-28 US US05/544,719 patent/US3997666A/en not_active Expired - Lifetime
- 1975-02-12 CA CA219,883A patent/CA1039282A/en not_active Expired
- 1975-02-17 GB GB656975A patent/GB1445548A/en not_active Expired
- 1975-02-18 FI FI750449A patent/FI59248C/fi not_active IP Right Cessation
- 1975-02-18 YU YU0382/75A patent/YU37156B/xx unknown
- 1975-02-18 ES ES434829A patent/ES434829A1/es not_active Expired
- 1975-02-18 NL NLAANVRAGE7501877,A patent/NL175059B/xx not_active IP Right Cessation
- 1975-02-18 DK DK58175A patent/DK135124C/da not_active IP Right Cessation
- 1975-02-19 ZA ZA00751031A patent/ZA751031B/xx unknown
- 1975-02-20 SE SE7501911A patent/SE405601B/xx not_active IP Right Cessation
- 1975-02-20 BE BE153540A patent/BE825755A/xx not_active IP Right Cessation
- 1975-02-20 JP JP50021386A patent/JPS6029712B2/ja not_active Expired
- 1975-02-21 SU SU2112509A patent/SU549085A3/ru active
- 1975-02-21 CH CH1023478A patent/CH612958A5/xx not_active IP Right Cessation
- 1975-02-21 PL PL1975178230A patent/PL92131B1/pl unknown
- 1975-02-21 IE IE359/75A patent/IE40678B1/xx unknown
- 1975-02-21 CH CH218575A patent/CH609342A5/xx not_active IP Right Cessation
- 1975-02-21 AT AT132375A patent/AT340937B/de not_active IP Right Cessation
- 1975-02-21 FR FR7505511A patent/FR2261770B1/fr not_active Expired
-
1976
- 1976-01-07 SU SU2308659A patent/SU561514A3/ru active
-
1981
- 1981-04-21 YU YU1044/81A patent/YU37157B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |