CH578545A5 - Cns-active 1-subst 1,4-benzodiazepin-2-ones - Google Patents

Cns-active 1-subst 1,4-benzodiazepin-2-ones

Info

Publication number
CH578545A5
CH578545A5 CH104576A CH104576A CH578545A5 CH 578545 A5 CH578545 A5 CH 578545A5 CH 104576 A CH104576 A CH 104576A CH 104576 A CH104576 A CH 104576A CH 578545 A5 CH578545 A5 CH 578545A5
Authority
CH
Switzerland
Prior art keywords
benzodiazepin
dihydro
chloro
acid
phenyl
Prior art date
Application number
CH104576A
Other languages
German (de)
English (en)
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of CH578545A5 publication Critical patent/CH578545A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH104576A 1970-06-24 1976-01-28 Cns-active 1-subst 1,4-benzodiazepin-2-ones CH578545A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5552970A JPS4831118B1 (enrdf_load_stackoverflow) 1970-06-24 1970-06-24

Publications (1)

Publication Number Publication Date
CH578545A5 true CH578545A5 (en) 1976-08-13

Family

ID=13001241

Family Applications (1)

Application Number Title Priority Date Filing Date
CH104576A CH578545A5 (en) 1970-06-24 1976-01-28 Cns-active 1-subst 1,4-benzodiazepin-2-ones

Country Status (6)

Country Link
JP (1) JPS4831118B1 (enrdf_load_stackoverflow)
AT (1) AT306733B (enrdf_load_stackoverflow)
CH (1) CH578545A5 (enrdf_load_stackoverflow)
CS (1) CS179398B2 (enrdf_load_stackoverflow)
HU (1) HU163792B (enrdf_load_stackoverflow)
PL (1) PL92569B1 (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
JPS4831118B1 (enrdf_load_stackoverflow) 1973-09-26
PL92569B1 (enrdf_load_stackoverflow) 1977-04-30
AT306733B (de) 1973-04-25
HU163792B (enrdf_load_stackoverflow) 1973-10-27
CS179398B2 (en) 1977-10-31

Similar Documents

Publication Publication Date Title
DE2037693A1 (de) Chinazolinderivate,verfahren zu ihrer herstellung und ihre verwendung
CH632511A5 (de) Verfahren zur herstellung von diazepinderivaten.
CH532065A (de) Verfahren zur Herstellung von Benzodiazepinderivaten
DE1955349C2 (de) s-Triazolo [4,3-a] [1,4] benzodiazepine
DE1920207A1 (de) Verfahren zur Herstellung von 1,4-Benzodiazepin-2-onverbindungen
CH578545A5 (en) Cns-active 1-subst 1,4-benzodiazepin-2-ones
DE2166472A1 (de) Verfahren zur herstellung von 1,3dihydro-2h-1,4-benzodiazepin-2-onen
EP0072029A2 (de) Triazolobenzazepine, Verfahren und Zwischenprodukte zu deren Herstellung und diese enthaltende Arzneimittel
DE1695211A1 (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten
DE2166504C3 (enrdf_load_stackoverflow)
DE2104571C3 (de) S-Phenyl-1,3-dihydro-2H-1,4benzodiazepin-2-one, ihre Salze und diese Verbindungen enthaltende Arzneipräparate
DE2141443C3 (de) U-Dihydro-S-phenyl^H-M-benzodiazepin-2-one, ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
CH581633A5 (en) Cns-active 1-subst 1,4-benzodiazepin-2-ones
DE2016385C3 (de) 1 -Alkoxyalkyl-5-(o-fluorphenyl)-7chlor-13-dihydro-2H-benzodiazepin-2-onderivate
DE2017060C3 (de) Verfahren zur Herstellung von 1,3-Dihydro-2H-1,4-benzodiazepinon-(2)derivaten
DE2166866C3 (de) 1 -Phenylalkoxyäthyl-13-dihydro-5phenyl-2H-1,4-benzodiazepin-2-one
DE2119717C3 (de) 14.05.70 Japan 41499-70 1-Alkoxyalkyl-5-(o-tolyl)-7-chlor-1,3-dihydro-2H-1 ^-benzodiazepin Verbindungen, ihre Salze, Verfahren zu ihrer Herstellung und diese Verbindungen
AT395154B (de) Verfahren zur herstellung von neuen imidazo(1,5-a)(1,4)diazepinverbindungen
DE2541464A1 (de) 1,2,4-triazolderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2104571A1 (de) Benzodiazepine, Verfahren zu ihrer Herstellung und Arzneipraparate
DE2204484A1 (de) Verfahren zur herstellung von 1,4benzodiazepinen
AT330787B (de) Verfahren zur herstellung von neuen diazepinderivaten und deren salzen
DE1795372C3 (de) 10.01.68 Japan 1501-68 Verfahren zur Herstellung von 5-(o-Halogenphenyl)-7-halogen-1,3-dihydro-2H-1,4-benzodiazepin-2-onen und 2-Aminomethylindole und ihre Salze
DE2129647C3 (de) Verfahren zur Herstellung von 1-Hydroxyalkyl-5-(o-halogenphenyl)-1,3dihydro-2 H -1,4-benzodiazepin-2-onderivaten
AT276400B (de) Verfahren zur Herstellung von neuen Benzodiazepin-Derivaten und von deren Säureadditionssalzen und quaternären Salzen

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased