CH416944A - Bariumsulfat enthaltendes Röntgenkontrastmittel - Google Patents
Bariumsulfat enthaltendes RöntgenkontrastmittelInfo
- Publication number
- CH416944A CH416944A CH371262A CH371262A CH416944A CH 416944 A CH416944 A CH 416944A CH 371262 A CH371262 A CH 371262A CH 371262 A CH371262 A CH 371262A CH 416944 A CH416944 A CH 416944A
- Authority
- CH
- Switzerland
- Prior art keywords
- suspension
- barium sulfate
- water
- contrast medium
- ray contrast
- Prior art date
Links
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 title claims description 44
- 239000002872 contrast media Substances 0.000 title claims description 21
- 239000000725 suspension Substances 0.000 claims description 44
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 239000000084 colloidal system Substances 0.000 claims description 18
- 230000001681 protective effect Effects 0.000 claims description 16
- 238000002360 preparation method Methods 0.000 claims description 14
- 230000009974 thixotropic effect Effects 0.000 claims description 13
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 10
- 241000195493 Cryptophyta Species 0.000 claims description 8
- 235000010443 alginic acid Nutrition 0.000 claims description 8
- 229920000615 alginic acid Polymers 0.000 claims description 8
- 150000004781 alginic acids Chemical class 0.000 claims description 8
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims description 8
- 229940075582 sorbic acid Drugs 0.000 claims description 8
- 235000010199 sorbic acid Nutrition 0.000 claims description 8
- 239000004334 sorbic acid Substances 0.000 claims description 8
- 238000003860 storage Methods 0.000 claims description 7
- 239000000783 alginic acid Substances 0.000 claims description 6
- 229960001126 alginic acid Drugs 0.000 claims description 6
- 125000000129 anionic group Chemical group 0.000 claims description 5
- 239000002270 dispersing agent Substances 0.000 claims description 5
- 239000000796 flavoring agent Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 241001474374 Blennius Species 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- 210000001072 colon Anatomy 0.000 claims description 4
- 238000010790 dilution Methods 0.000 claims description 4
- 239000012895 dilution Substances 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- 239000000243 solution Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 239000000341 volatile oil Substances 0.000 claims description 4
- 241000206572 Rhodophyta Species 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 230000032050 esterification Effects 0.000 claims description 3
- 238000005886 esterification reaction Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- -1 propylene glycol ester Chemical class 0.000 claims description 3
- 230000028327 secretion Effects 0.000 claims description 3
- 238000001694 spray drying Methods 0.000 claims description 3
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 claims description 2
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 claims description 2
- 150000007513 acids Chemical class 0.000 claims description 2
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 claims description 2
- 238000003745 diagnosis Methods 0.000 claims description 2
- 238000007865 diluting Methods 0.000 claims description 2
- IDAGXRIGDWCIET-SDFKWCIISA-L disodium;(2s,3s,4s,5r)-2,3,4,5-tetrahydroxyhexanedioate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O IDAGXRIGDWCIET-SDFKWCIISA-L 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 210000003238 esophagus Anatomy 0.000 claims description 2
- 235000019634 flavors Nutrition 0.000 claims description 2
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- 230000002496 gastric effect Effects 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims description 2
- 238000009928 pasteurization Methods 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims description 2
- 229960001462 sodium cyclamate Drugs 0.000 claims description 2
- 239000002344 surface layer Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 4
- 239000000654 additive Substances 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 230000002335 preservative effect Effects 0.000 claims 2
- 230000000996 additive effect Effects 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000000047 product Substances 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 125000002843 carboxylic acid group Chemical group 0.000 description 1
- 229940039231 contrast media Drugs 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0404—X-ray contrast preparations containing barium sulfate
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE3402/61A SE309650B (enrdf_load_stackoverflow) | 1961-03-30 | 1961-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH416944A true CH416944A (de) | 1966-07-15 |
Family
ID=20262040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH371262A CH416944A (de) | 1961-03-30 | 1962-03-28 | Bariumsulfat enthaltendes Röntgenkontrastmittel |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE615785A (enrdf_load_stackoverflow) |
| CH (1) | CH416944A (enrdf_load_stackoverflow) |
| FI (1) | FI40198C (enrdf_load_stackoverflow) |
| FR (1) | FR3723M (enrdf_load_stackoverflow) |
| GB (1) | GB998331A (enrdf_load_stackoverflow) |
| SE (1) | SE309650B (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE348372B (enrdf_load_stackoverflow) * | 1970-12-18 | 1972-09-04 | Astra Laekemedel Ab | |
| US4069306A (en) * | 1974-03-14 | 1978-01-17 | Pharmacia Aktiebolag | X-ray contrast preparation containing a hydrophilic polymer containing amino groups |
-
1961
- 1961-03-30 SE SE3402/61A patent/SE309650B/xx unknown
-
1962
- 1962-03-21 GB GB10894/62A patent/GB998331A/en not_active Expired
- 1962-03-23 FI FI61462A patent/FI40198C/fi active
- 1962-03-28 CH CH371262A patent/CH416944A/de unknown
- 1962-03-29 BE BE615785A patent/BE615785A/fr unknown
- 1962-06-12 FR FR892717A patent/FR3723M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| GB998331A (en) | 1965-07-14 |
| FR3723M (fr) | 1965-12-06 |
| BE615785A (fr) | 1962-10-01 |
| FI40198B (enrdf_load_stackoverflow) | 1968-07-31 |
| SE309650B (enrdf_load_stackoverflow) | 1969-03-31 |
| FI40198C (fi) | 1968-11-11 |
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