CH408045A - Verfahren zur Herstellung von Benzophenonderivaten - Google Patents

Verfahren zur Herstellung von Benzophenonderivaten

Info

Publication number
CH408045A
CH408045A CH1230565A CH1230565A CH408045A CH 408045 A CH408045 A CH 408045A CH 1230565 A CH1230565 A CH 1230565A CH 1230565 A CH1230565 A CH 1230565A CH 408045 A CH408045 A CH 408045A
Authority
CH
Switzerland
Prior art keywords
preparation
benzophenone derivatives
benzophenone
derivatives
Prior art date
Application number
CH1230565A
Other languages
German (de)
English (en)
Inventor
Henryk Sternbach Leo
Keller Oscar
Steiger Norbert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH408045A publication Critical patent/CH408045A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH1230565A 1959-12-10 1960-12-02 Verfahren zur Herstellung von Benzophenonderivaten CH408045A (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85856459A 1959-12-10 1959-12-10
US260560A 1960-01-15 1960-01-15
US2468660A 1960-04-26 1960-04-26
US3873260A 1960-06-27 1960-06-27

Publications (1)

Publication Number Publication Date
CH408045A true CH408045A (de) 1966-02-28

Family

ID=27485190

Family Applications (9)

Application Number Title Priority Date Filing Date
CH1230565A CH408045A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von Benzophenonderivaten
CH1349060A CH411910A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1349260A CH418341A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349160A CH408029A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349360A CH418342A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349560A CH414653A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1349460A CH414652A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1348960A CH408940A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1389960A CH396016A (de) 1959-12-10 1960-12-13 Verfahren zur Herstellung von fluorhaltigen Benzodiazepinen

Family Applications After (8)

Application Number Title Priority Date Filing Date
CH1349060A CH411910A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1349260A CH418341A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349160A CH408029A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349360A CH418342A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH1349560A CH414653A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1349460A CH414652A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1348960A CH408940A (de) 1959-12-10 1960-12-02 Verfahren zur Herstellung von 1,4-Benzodiazepin-Derivaten
CH1389960A CH396016A (de) 1959-12-10 1960-12-13 Verfahren zur Herstellung von fluorhaltigen Benzodiazepinen

Country Status (11)

Country Link
BE (4) BE598012A (enExample)
BR (1) BR6024755D0 (enExample)
CH (9) CH408045A (enExample)
CY (1) CY324A (enExample)
DE (5) DE1288609B (enExample)
ES (2) ES263123A1 (enExample)
GB (13) GB972976A (enExample)
MY (1) MY6500178A (enExample)
NL (2) NL6412250A (enExample)
OA (7) OA00817A (enExample)
SE (2) SE310887B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014132018A (ja) * 2002-05-24 2014-07-17 Millennium Pharmaceuticals Inc Ccr9インヒビターおよびその使用方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1295563B (de) * 1963-05-29 1969-05-22 American Home Prod Verfahren zur Herstellung von 5-Phenyl-7-chlor-1, 2-dihydro-3H-1, 4-benzodiazepinon-(2)-4-oxyd
GB1333501A (en) * 1971-03-05 1973-10-10 Ravizza Spa Process for the preparation of 7-chlorobenzodiazepine de rivatives
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
JP2005503356A (ja) * 2001-06-07 2005-02-03 ニューロ3デー 環状ヌクレオチドホスホジエステラーゼ阻害剤、その製造および使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2893992A (en) * 1959-07-07 I ii i i

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014132018A (ja) * 2002-05-24 2014-07-17 Millennium Pharmaceuticals Inc Ccr9インヒビターおよびその使用方法

Also Published As

Publication number Publication date
GB972966A (en) 1964-10-21
GB972965A (en) 1964-10-21
DE1445908A1 (de) 1969-04-17
OA00817A (fr) 1967-11-15
DE1290143B (de) 1969-03-06
ES263124A1 (es) 1961-06-01
GB972973A (en) 1964-10-21
CH418341A (de) 1966-08-15
GB972967A (en) 1964-10-21
GB972964A (en) 1964-10-21
GB972961A (en) 1964-10-21
DE1288609B (de) 1969-02-06
CY324A (en) 1965-11-03
OA02384A (fr) 1970-05-05
NL6412251A (enExample) 1966-01-25
BE598015A (fr) 1961-06-09
BR6024755D0 (pt) 1973-05-24
CH414652A (de) 1966-06-15
GB972970A (en) 1964-10-21
DE1288610B (de) 1969-02-06
CH418342A (de) 1966-08-15
CH408940A (de) 1966-03-15
CH396016A (de) 1965-07-31
GB972969A (en) 1964-10-21
MY6500178A (en) 1965-12-31
CH408029A (de) 1966-02-28
ES263123A1 (es) 1961-06-01
GB972962A (en) 1964-10-21
NL6412250A (enExample) 1966-01-25
CH414653A (de) 1966-06-15
GB972963A (en) 1964-10-21
GB972972A (en) 1964-10-21
OA02385A (fr) 1970-05-05
BE598013A (fr) 1961-06-09
GB972976A (en) 1964-10-21
OA00816A (fr) 1967-11-15
BE598008A (fr) 1961-06-09
DE1445073A1 (de) 1968-10-31
OA00953A (fr) 1968-03-22
GB972968A (en) 1964-10-21
SE318283B (enExample) 1969-12-08
BE598012A (fr) 1961-06-09
OA00959A (fr) 1968-03-22
OA00958A (fr) 1968-03-22
CH411910A (de) 1966-04-30
SE310887B (enExample) 1969-05-19

Similar Documents

Publication Publication Date Title
CH370197A (de) Verfahren zur Herstellung von Actinospectacin
CH387047A (de) Verfahren zur Herstellung von Ketosidopurinen
CH400144A (de) Verfahren zur Herstellung von 16-Methylen-17a-hydroxy-progesteron-17-acylaten
CH419127A (de) Verfahren zur Herstellung von substituierten 3-Pyrrolidinolen
CH404962A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH396026A (de) Verfahren zur Herstellung von Halogenalkylaminen
CH387606A (de) Verfahren zur Herstellung von Tetrahydroxydibor
CH399742A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH387029A (de) Verfahren zur Herstellung von 9a-Fluor-11B-oxy-16a-methylprogesteron
CH440249A (de) Verfahren zur Herstellung von Polychlorbenzonitrilen
CH387048A (de) Verfahren zur Herstellung von 7-Theophyllinderivaten
CH380730A (de) Verfahren zur Herstellung von 4-Methoxy-2-methyl-6-sulfanilamidopyrimidin
CH538458A (de) Verfahren zur Herstellung von a-Dithiosemicarbazonen
CH417595A (de) Verfahren zur Herstellung von Alkyl-5-alkylisoxazol-3-carboxylaten
CH416113A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH372297A (de) Verfahren zur Herstellung von 4-2-tert.-Aminomethyl-3-keto-steroiden
CH414663A (de) Verfahren zur Herstellung von D- und L-Morphinanderivaten
CH400110A (de) Verfahren zur Herstellung von 2-Trifluormethylbenzhydrol
CH378344A (de) Verfahren zur Herstellung von 2-Amino-anthrachinonen
CH405316A (de) Verfahren zur Herstellung von 3-Amino-2-oxazolidonderivaten
CH387050A (de) Verfahren zur Herstellung von Benzo-dihydrothiadiazin-Derivaten
CH406205A (de) Verfahren zur Herstellung von 16a-Halomethylderivaten von 17a-Hydroxy-20-keto-pregnanen
AT221092B (de) Verfahren zur Herstellung von substituierten 2-Oxo-benzochinolizinen
AT221096B (de) Verfahren zur Herstellung von 2-Hydrazino-3-mercapto-chinoxalin
AT221494B (de) Verfahren zur Herstellung von α-Amino-ω-lactamen