CA3239386A1 - Increasing drug bioavailability in naltrexone therapy - Google Patents

Increasing drug bioavailability in naltrexone therapy

Info

Publication number
CA3239386A1
CA3239386A1 CA3239386A CA3239386A CA3239386A1 CA 3239386 A1 CA3239386 A1 CA 3239386A1 CA 3239386 A CA3239386 A CA 3239386A CA 3239386 A CA3239386 A CA 3239386A CA 3239386 A1 CA3239386 A1 CA 3239386A1
Authority
CA
Canada
Prior art keywords
acceptable salt
pharmaceutically acceptable
naltrexone
bupropion
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3239386A
Other languages
English (en)
French (fr)
Inventor
Shawn Flanagan
Eduardo Dunayevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nalpropion Pharmaceuticals LLC
Original Assignee
Nalpropion Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46172304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3239386(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nalpropion Pharmaceuticals LLC filed Critical Nalpropion Pharmaceuticals LLC
Publication of CA3239386A1 publication Critical patent/CA3239386A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acoustics & Sound (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
CA3239386A 2010-12-03 2011-12-02 Increasing drug bioavailability in naltrexone therapy Pending CA3239386A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41939510P 2010-12-03 2010-12-03
US61/419,395 2010-12-03
CA2819262A CA2819262C (en) 2010-12-03 2011-12-02 Pharmaceutical composition comprising naltrexone and buopropion for administration with food

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2819262A Division CA2819262C (en) 2010-12-03 2011-12-02 Pharmaceutical composition comprising naltrexone and buopropion for administration with food

Publications (1)

Publication Number Publication Date
CA3239386A1 true CA3239386A1 (en) 2012-06-07

Family

ID=46172304

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3239386A Pending CA3239386A1 (en) 2010-12-03 2011-12-02 Increasing drug bioavailability in naltrexone therapy
CA2819262A Active CA2819262C (en) 2010-12-03 2011-12-02 Pharmaceutical composition comprising naltrexone and buopropion for administration with food

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2819262A Active CA2819262C (en) 2010-12-03 2011-12-02 Pharmaceutical composition comprising naltrexone and buopropion for administration with food

Country Status (27)

Country Link
US (1) US20130245056A1 (enExample)
EP (5) EP3222280B1 (enExample)
JP (5) JP6008866B2 (enExample)
KR (5) KR101984500B1 (enExample)
CN (1) CN103313711A (enExample)
AR (2) AR093182A1 (enExample)
AU (2) AU2011336304B2 (enExample)
BR (1) BR112013013390A2 (enExample)
CA (2) CA3239386A1 (enExample)
CL (1) CL2013001564A1 (enExample)
CY (2) CY1118968T1 (enExample)
DK (4) DK2646031T3 (enExample)
ES (3) ES2866879T3 (enExample)
FI (2) FI4349369T3 (enExample)
HR (4) HRP20251576T1 (enExample)
HU (3) HUE034393T2 (enExample)
IL (3) IL226504B (enExample)
LT (4) LT2646031T (enExample)
MX (2) MX356801B (enExample)
PL (3) PL2646031T3 (enExample)
PT (4) PT4349369T (enExample)
RS (4) RS56014B1 (enExample)
RU (1) RU2640561C2 (enExample)
SI (4) SI3222280T1 (enExample)
SM (4) SMT202100227T1 (enExample)
TW (1) TWI618536B (enExample)
WO (1) WO2012075459A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2350327C2 (ru) 2003-04-29 2009-03-27 Ориксиджен Серапьютикс, Инкорпорэйтд Составы, вызывающие потерю веса
EP1951212A2 (en) 2005-11-22 2008-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
EP2303025A4 (en) 2008-05-30 2012-07-04 Orexigen Therapeutics Inc METHOD FOR TREATING DIGITAL FAT SWITCHES
EP3659604A1 (en) 2010-01-11 2020-06-03 Nalpropion Pharmaceuticals, Inc. Methods of providing weight loss therapy in patients with major depression
TWI618536B (zh) * 2010-12-03 2018-03-21 歐瑞根治療有限公司 於納曲酮療法中增加藥物生物可利用性
PT3730132T (pt) 2012-06-06 2022-08-16 Nalpropion Pharmaceuticals Llc Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular
US20180015042A1 (en) * 2015-02-07 2018-01-18 Intas Pharmaceuticals Ltd. Pharmaceutical composition for the treatment of obesity
KR20200072445A (ko) * 2017-03-28 2020-06-22 엘디엔 파마 리미티드 암의 치료를 위한 세포 사멸의 bcl2-관련 효능제의 발현을 증가시키는 제제
EP3482751A1 (en) 2017-11-14 2019-05-15 LDN Pharma Limited Cancer treatment
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
US6972291B2 (en) * 2002-07-02 2005-12-06 Bernstein Richard K Method for reducing food intake
EP1772147A2 (en) * 2003-03-17 2007-04-11 Japan Tobacco, Inc. Method for increasing the oral bioavailability of S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
RU2350327C2 (ru) 2003-04-29 2009-03-27 Ориксиджен Серапьютикс, Инкорпорэйтд Составы, вызывающие потерю веса
BRPI0613911A2 (pt) 2005-07-27 2011-02-22 Orexigen Therapeutics Inc composições para afetar a perda de peso
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
EP1951212A2 (en) 2005-11-22 2008-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
WO2007089318A2 (en) 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
TW200803901A (en) 2005-11-28 2008-01-16 Orexigen Therapeutics Inc Methods of treating anxiety disorders
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
EP2719378B1 (en) * 2006-06-19 2016-08-31 Alpharma Pharmaceuticals LLC Pharmaceutical compositions
KR101264789B1 (ko) 2006-06-30 2013-05-15 엘지디스플레이 주식회사 횡전계 방식 액정표시장치용 어레이 기판과 그 제조방법
CA2693992C (en) * 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
TW201811315A (zh) 2006-11-09 2018-04-01 美商歐瑞根治療有限公司 層狀醫藥調配物
CA2668885C (en) 2006-11-09 2016-08-02 Orexigen Therapeutics, Inc. Methods for administering weight loss medications
HRP20220188T3 (hr) * 2007-04-11 2022-04-29 Biomarin Pharmaceutical Inc. Načini primjene tetrahidrobiopterina, povezani pripravci i postupci mjerenja
DE102007036076A1 (de) 2007-08-01 2009-02-05 Bayer Healthcare Aktiengesellschaft Dipeptoid-Produgs und ihre Verwendung
US8318813B2 (en) * 2007-09-13 2012-11-27 Lcs Group, Llc Method of treating binge eating disorder
EP2303025A4 (en) 2008-05-30 2012-07-04 Orexigen Therapeutics Inc METHOD FOR TREATING DIGITAL FAT SWITCHES
TWI618536B (zh) 2010-12-03 2018-03-21 歐瑞根治療有限公司 於納曲酮療法中增加藥物生物可利用性

Also Published As

Publication number Publication date
RS65198B1 (sr) 2024-03-29
BR112013013390A2 (pt) 2016-09-06
CA2819262A1 (en) 2012-06-07
DK4349369T3 (da) 2025-12-22
AU2011336304A1 (en) 2013-07-11
MX384662B (es) 2025-03-14
SI2646031T1 (sl) 2017-07-31
WO2012075459A1 (en) 2012-06-07
PT3222280T (pt) 2021-04-22
AU2017204309A1 (en) 2017-07-13
EP3222280A1 (en) 2017-09-27
LT3222280T (lt) 2021-05-10
EP2646031A4 (en) 2014-04-23
ES2625527T3 (es) 2017-07-19
FI3884947T3 (fi) 2024-01-30
FI4349369T3 (fi) 2025-12-17
DK2646031T3 (en) 2017-05-22
SI3884947T1 (sl) 2024-06-28
PT4349369T (pt) 2025-12-17
PL3884947T3 (pl) 2024-05-06
LT4349369T (lt) 2026-01-12
DK3884947T3 (da) 2024-01-22
EP2646031B1 (en) 2017-02-22
RU2017144631A (ru) 2019-02-18
KR102258043B1 (ko) 2021-05-28
KR102391511B1 (ko) 2022-04-26
EP4696322A2 (en) 2026-02-18
MX2013006071A (es) 2013-10-01
KR20200044158A (ko) 2020-04-28
EP4349369A3 (en) 2024-05-15
CY1118968T1 (el) 2018-01-10
SMT201700232T1 (it) 2017-07-18
ES2866879T3 (es) 2021-10-20
RU2013127423A (ru) 2015-01-10
PL2646031T3 (pl) 2017-08-31
RS56014B1 (sr) 2017-09-29
JP2024071605A (ja) 2024-05-24
JP6008866B2 (ja) 2016-10-19
KR20210063473A (ko) 2021-06-01
KR102105857B1 (ko) 2020-05-04
CN103313711A (zh) 2013-09-18
JP2013544290A (ja) 2013-12-12
CY1124331T1 (el) 2022-07-22
PT2646031T (pt) 2017-05-25
IL279626A (en) 2021-03-01
TW201304780A (zh) 2013-02-01
EP3222280B1 (en) 2021-01-20
LT3884947T (lt) 2024-03-12
KR101984500B1 (ko) 2019-05-31
CA2819262C (en) 2024-05-28
LT2646031T (lt) 2017-06-26
KR20140035320A (ko) 2014-03-21
EP4349369B1 (en) 2025-09-17
KR20190058702A (ko) 2019-05-29
CL2013001564A1 (es) 2014-05-02
RU2017144631A3 (enExample) 2021-04-13
SI3222280T1 (sl) 2021-11-30
IL226504B (en) 2021-01-31
SI4349369T1 (sl) 2026-02-27
IL270841A (en) 2020-01-30
SMT202400038T1 (it) 2024-03-13
DK3222280T3 (da) 2021-04-19
ES3056642T3 (en) 2026-02-23
RS67527B1 (sr) 2026-01-30
PL3222280T3 (pl) 2021-11-29
AR124500A2 (es) 2023-04-05
HRP20210618T1 (hr) 2021-09-17
US20130245056A1 (en) 2013-09-19
HUE065852T2 (hu) 2024-06-28
JP2016210809A (ja) 2016-12-15
EP2646031B9 (en) 2018-01-10
AR093182A1 (es) 2015-05-27
HUE034393T2 (en) 2018-02-28
EP3884947A1 (en) 2021-09-29
SMT202100227T1 (it) 2021-07-12
TWI618536B (zh) 2018-03-21
HUE053831T2 (hu) 2021-07-28
EP4349369A2 (en) 2024-04-10
JP2022060331A (ja) 2022-04-14
EP2646031A1 (en) 2013-10-09
JP7025319B2 (ja) 2022-02-24
JP2019056004A (ja) 2019-04-11
SMT202500474T1 (it) 2026-01-12
EP3884947B1 (en) 2023-11-15
RS62149B1 (sr) 2021-08-31
JP6456890B2 (ja) 2019-01-23
PT3884947T (pt) 2024-02-16
HRP20240115T1 (hr) 2024-06-07
KR20180069089A (ko) 2018-06-22
RU2640561C2 (ru) 2018-01-09
AU2011336304B2 (en) 2017-03-30
HRP20170734T1 (hr) 2017-08-11
MX356801B (es) 2018-06-13
ES2625527T9 (es) 2018-09-25
HRP20251576T1 (hr) 2026-01-30

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