CA3231307A1 - Recombinant microorganism used for producing cdp-choline, and method for producing cdp-choline using said recombinant microorganism - Google Patents
Recombinant microorganism used for producing cdp-choline, and method for producing cdp-choline using said recombinant microorganism Download PDFInfo
- Publication number
- CA3231307A1 CA3231307A1 CA3231307A CA3231307A CA3231307A1 CA 3231307 A1 CA3231307 A1 CA 3231307A1 CA 3231307 A CA3231307 A CA 3231307A CA 3231307 A CA3231307 A CA 3231307A CA 3231307 A1 CA3231307 A1 CA 3231307A1
- Authority
- CA
- Canada
- Prior art keywords
- ctp
- choline
- dna
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07015—Choline-phosphate cytidylyltransferase (2.7.7.15)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021-147985 | 2021-09-10 | ||
| JP2021147985 | 2021-09-10 | ||
| PCT/JP2022/033972 WO2023038128A1 (ja) | 2021-09-10 | 2022-09-09 | Ｃｄｐ－コリンの製造に用いる組換え微生物及び該組換え微生物を用いるｃｄｐ－コリンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3231307A1 true CA3231307A1 (en) | 2023-03-16 |
Family
ID=85506465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3231307A Pending CA3231307A1 (en) | 2021-09-10 | 2022-09-09 | Recombinant microorganism used for producing cdp-choline, and method for producing cdp-choline using said recombinant microorganism |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250043255A1 (https=) |
| EP (1) | EP4400588A4 (https=) |
| JP (1) | JPWO2023038128A1 (https=) |
| KR (1) | KR20240043794A (https=) |
| CN (1) | CN117916378A (https=) |
| AU (1) | AU2022344719B2 (https=) |
| CA (1) | CA3231307A1 (https=) |
| WO (1) | WO2023038128A1 (https=) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58110600A (ja) | 1981-12-25 | 1983-07-01 | Kyowa Hakko Kogyo Co Ltd | ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド |
| JP2545078B2 (ja) | 1987-04-06 | 1996-10-16 | 協和醗酵工業株式会社 | 核酸関連物質の製造法 |
| JP3369236B2 (ja) | 1992-01-30 | 2003-01-20 | 協和醗酵工業株式会社 | シチジンジリン酸コリンの製造法 |
| KR100555161B1 (ko) | 1996-09-17 | 2006-11-30 | 교와 핫꼬 고교 가부시끼가이샤 | 당뉴클레오티드류및복합당질의제조법 |
| US20050164359A1 (en) | 2002-05-08 | 2005-07-28 | Hashimoto Shin-Ichi | Process for producing cytidine 5'-diphosphate choline |
| KR20070023830A (ko) | 2005-08-23 | 2007-03-02 | 주식회사 엘티아이 | 발광다이오드를 광원으로 사용하는 백라이트 유닛 및 그의결선 방법 |
| JP5112869B2 (ja) | 2005-08-23 | 2013-01-09 | 協和発酵バイオ株式会社 | シチジンジリン酸コリンの製造法 |
| CN104774799B (zh) * | 2015-04-17 | 2018-01-30 | 南京工业大学 | 一株表达胆碱激酶及磷酰胆碱胞苷转移酶的基因工程菌及其构建方法与应用 |
| CN109207415B (zh) * | 2017-07-07 | 2022-09-16 | 苏州华赛生物工程技术有限公司 | 一种生产胞二磷胆碱的重组微生物及生产胞二磷胆碱的方法 |
| JP7401368B2 (ja) | 2020-03-24 | 2023-12-19 | フルテック株式会社 | 自動ドア |
-
2022
- 2022-09-09 CA CA3231307A patent/CA3231307A1/en active Pending
- 2022-09-09 CN CN202280060889.5A patent/CN117916378A/zh active Pending
- 2022-09-09 JP JP2023547014A patent/JPWO2023038128A1/ja active Pending
- 2022-09-09 AU AU2022344719A patent/AU2022344719B2/en active Active
- 2022-09-09 EP EP22867449.5A patent/EP4400588A4/en active Pending
- 2022-09-09 US US18/690,373 patent/US20250043255A1/en active Pending
- 2022-09-09 WO PCT/JP2022/033972 patent/WO2023038128A1/ja not_active Ceased
- 2022-09-09 KR KR1020247007949A patent/KR20240043794A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240043794A (ko) | 2024-04-03 |
| WO2023038128A1 (ja) | 2023-03-16 |
| EP4400588A4 (en) | 2025-10-08 |
| US20250043255A1 (en) | 2025-02-06 |
| AU2022344719A1 (en) | 2024-03-28 |
| CN117916378A (zh) | 2024-04-19 |
| EP4400588A1 (en) | 2024-07-17 |
| AU2022344719B2 (en) | 2025-12-11 |
| JPWO2023038128A1 (https=) | 2023-03-16 |
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| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20240308 |
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| D15 | Examination report completed |
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