CA3198255A1 - Ctla-4 variant immunomodulatory proteins and uses thereof - Google Patents
Ctla-4 variant immunomodulatory proteins and uses thereofInfo
- Publication number
- CA3198255A1 CA3198255A1 CA3198255A CA3198255A CA3198255A1 CA 3198255 A1 CA3198255 A1 CA 3198255A1 CA 3198255 A CA3198255 A CA 3198255A CA 3198255 A CA3198255 A CA 3198255A CA 3198255 A1 CA3198255 A1 CA 3198255A1
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- Prior art keywords
- polypeptide
- ctla
- cell
- domain
- variant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| PT3283508T (pt) | 2015-04-17 | 2021-06-21 | Alpine Immune Sciences Inc | Proteínas imuno modulatórias com afinidades afináveis |
| CA3198255A1 (en) | 2017-10-10 | 2019-04-18 | Alpine Immune Sciences, Inc. | Ctla-4 variant immunomodulatory proteins and uses thereof |
| WO2019136179A1 (en) | 2018-01-03 | 2019-07-11 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| EP3856247A4 (en) * | 2018-11-02 | 2022-07-06 | Beijing Vdjbio Co., Ltd. | MODIFIED CTLA4 AND METHODS OF USE |
| JP7650047B2 (ja) * | 2019-11-27 | 2025-03-24 | 株式会社 MiyaCare Therapeutics | 変異型結合性タンパク質の製造方法及び変異型pd-1 |
| PE20230494A1 (es) | 2020-05-08 | 2023-03-23 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras inhibidoras de april y baff y metodos de uso de las mismas |
| CN111592580A (zh) * | 2020-05-08 | 2020-08-28 | 中国药科大学 | 一种具有免疫检查点ctla-4抑制活性的多肽及其应用 |
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| CN119679395B (zh) * | 2024-12-04 | 2025-09-23 | 山东大学 | 一种基于动力学图融合的腺样体肥大辅助检测系统及方法 |
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