CA3095576A1 - Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts - Google Patents

Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts

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Publication number
CA3095576A1
CA3095576A1 CA3095576A CA3095576A CA3095576A1 CA 3095576 A1 CA3095576 A1 CA 3095576A1 CA 3095576 A CA3095576 A CA 3095576A CA 3095576 A CA3095576 A CA 3095576A CA 3095576 A1 CA3095576 A1 CA 3095576A1
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CA
Canada
Prior art keywords
cell
cells
culture media
stem cell
pluripotent stem
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3095576A
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English (en)
French (fr)
Inventor
Erin Kimberel
Shi-Jiang Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Institute for Regenerative Medicine
Original Assignee
Astellas Institute for Regenerative Medicine
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Filing date
Publication date
Application filed by Astellas Institute for Regenerative Medicine filed Critical Astellas Institute for Regenerative Medicine
Publication of CA3095576A1 publication Critical patent/CA3095576A1/en
Pending legal-status Critical Current

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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CA3095576A 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts Pending CA3095576A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26666109P 2009-12-04 2009-12-04
US61/266,661 2009-12-04
CA2781969A CA2781969A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2781969A Division CA2781969A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts

Publications (1)

Publication Number Publication Date
CA3095576A1 true CA3095576A1 (en) 2011-06-09

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Application Number Title Priority Date Filing Date
CA3095576A Pending CA3095576A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
CA2781969A Abandoned CA2781969A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
CA3080368A Abandoned CA3080368A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts

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CA2781969A Abandoned CA2781969A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
CA3080368A Abandoned CA3080368A1 (en) 2009-12-04 2010-12-01 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts

Country Status (11)

Country Link
US (3) US8822218B2 (https=)
EP (1) EP2507365A4 (https=)
JP (5) JP6013187B2 (https=)
KR (5) KR20250048382A (https=)
CN (1) CN102822332A (https=)
AU (1) AU2010326027A1 (https=)
BR (1) BR112012014104A2 (https=)
CA (3) CA3095576A1 (https=)
IN (1) IN2012DN05053A (https=)
RU (1) RU2012127811A (https=)
WO (1) WO2011068896A1 (https=)

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CA3095576A1 (en) 2009-12-04 2011-06-09 Astellas Institute For Regenerative Medicine Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
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CN105219717A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种一型极化树突状细胞及其诱导方法和应用
CN105219722A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种用于激活肾癌特异性免疫反应的试剂盒
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CN105219728A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种用于激活乳腺癌特异性免疫反应的试剂盒
CN105219723A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种用于激活胃癌特异性免疫反应的试剂盒
CN105219726A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种高效制备一型极化树突状细胞的方法及其应用
CN105219716A (zh) * 2015-10-20 2016-01-06 上海隆耀生物科技有限公司 一种用于激活头颈部癌特异性免疫反应的试剂盒
KR102167548B1 (ko) * 2017-09-21 2020-10-19 한국생명공학연구원 자연살해세포의 제조방법 및 그의 용도
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