CA3047321A1 - Polymerizing enzymes for sequencing reactions - Google Patents
Polymerizing enzymes for sequencing reactions Download PDFInfo
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- CA3047321A1 CA3047321A1 CA3047321A CA3047321A CA3047321A1 CA 3047321 A1 CA3047321 A1 CA 3047321A1 CA 3047321 A CA3047321 A CA 3047321A CA 3047321 A CA3047321 A CA 3047321A CA 3047321 A1 CA3047321 A1 CA 3047321A1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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| US10865441B2 (en) * | 2019-03-13 | 2020-12-15 | Abclonal Science, Inc. | Mutant Taq polymerase for faster amplification |
| SG11202112620TA (en) * | 2019-05-17 | 2021-12-30 | 4basebio Sl | Phi29 dna polymerase mutants with improved primer recognition |
| MX2022000055A (es) * | 2019-06-28 | 2022-05-30 | Quantum Si Inc | Enzimas de polimerización para reacciones de secuenciación. |
| AU2020364058A1 (en) | 2019-10-11 | 2022-05-26 | Quantum-Si Incorporated | Surface modification in the vapor phase |
| CN115362266A (zh) * | 2020-02-10 | 2022-11-18 | 铂赛基因组学公司 | Phi29突变体及其用途 |
| JP2023554368A (ja) | 2020-12-15 | 2023-12-27 | クアンタム－エスアイ インコーポレイテッド | 単一分子速度論による分子バーコード分析 |
| CN116083393B (zh) * | 2023-02-14 | 2025-09-23 | 南方科技大学 | 一种dna装配分子机器及其应用 |
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| CN119082075B (zh) * | 2024-09-12 | 2025-06-27 | 湖南艾科瑞生物工程有限公司 | 性能提升的phi29 DNA聚合酶突变体及其制备方法与应用 |
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| DE4435728A1 (de) | 1994-01-19 | 1995-07-20 | Boehringer Mannheim Gmbh | Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix |
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| EP1490483B1 (en) | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
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| US7745116B2 (en) | 2003-04-08 | 2010-06-29 | Pacific Biosciences Of California, Inc. | Composition and method for nucleic acid sequencing |
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| DE602006016984D1 (de) | 2005-12-12 | 2010-10-28 | Us Gov Health & Human Serv | Sonde zum sequenzieren von nukleinsäure und verwendungsverfahren |
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| CN102084001B (zh) | 2008-03-28 | 2015-03-18 | 加利福尼亚太平洋生物科学股份有限公司 | 用于核酸测序的组合物和方法 |
| US9127259B2 (en) * | 2008-03-31 | 2015-09-08 | Pacific Biosciences Of California, Inc. | Enzymes resistant to photodamage |
| US8420366B2 (en) | 2008-03-31 | 2013-04-16 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
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| DE102009013653B4 (de) | 2009-03-18 | 2014-09-18 | Bruker Daltonik Gmbh | Protein-Sequenzierung mit MALDI-Massenspektrometrie |
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| JP7418323B2 (ja) | 2017-08-24 | 2024-01-19 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 遠赤および近ｉｒ範囲におけるシアニンフルオロフォアの配座の束縛 |
| US10836798B2 (en) | 2018-11-08 | 2020-11-17 | Government Of The United States Of America, As Represented By The Secretary Of Commerce | Amino acid-specific binder and selectively identifying an amino acid |
| MX2022000055A (es) * | 2019-06-28 | 2022-05-30 | Quantum Si Inc | Enzimas de polimerización para reacciones de secuenciación. |
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| EP3555272A2 (en) | 2019-10-23 |
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| TW201835328A (zh) | 2018-10-01 |
| AU2017378990A1 (en) | 2019-06-20 |
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