CA3037086A1 - Hpv-specific binding molecules - Google Patents
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- CA3037086A1 CA3037086A1 CA3037086A CA3037086A CA3037086A1 CA 3037086 A1 CA3037086 A1 CA 3037086A1 CA 3037086 A CA3037086 A CA 3037086A CA 3037086 A CA3037086 A CA 3037086A CA 3037086 A1 CA3037086 A1 CA 3037086A1
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K—PEPTIDES
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/624—Disulfide-stabilized antibody (dsFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116157528A (zh) * | 2021-09-07 | 2023-05-23 | 北京可瑞生物科技有限公司 | 抗原结合蛋白及其用途 |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB201417803D0 (en) * | 2014-10-08 | 2014-11-19 | Adaptimmune Ltd | T cell receptors |
| WO2017096329A1 (en) | 2015-12-03 | 2017-06-08 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| WO2018143454A1 (ja) * | 2017-02-06 | 2018-08-09 | 国立研究開発法人国立がん研究センター | 新規ｔ細胞受容体 |
| GB201709866D0 (en) * | 2017-06-20 | 2017-08-02 | Immunocore Ltd | T cell receptors |
| US10806780B2 (en) | 2017-06-28 | 2020-10-20 | Regeneron Pharmaceuticals, Inc. | Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof |
| WO2019070541A1 (en) | 2017-10-03 | 2019-04-11 | Juno Therapeutics, Inc. | HPV-SPECIFIC BINDING MOLECULES |
| RU2020135968A (ru) | 2018-04-05 | 2022-05-06 | Джуно Терапьютикс, Инк. | T-клеточные рецепторы и модифицированные клетки, экспрессирующие |
| EP3784255B1 (en) * | 2018-04-19 | 2025-09-17 | Board of Regents, The University of Texas System | T cell receptors with mage-b2 specificity and uses thereof |
| EP3810780A1 (en) * | 2018-06-22 | 2021-04-28 | Kite Pharma Eu B.V. | Compositions and methods for making engineered t cells |
| AU2019321271A1 (en) * | 2018-08-11 | 2021-02-11 | Guangdong Tcrcure Biopharma Technology Co., Ltd. | Dual function engineered T cells with HPV E6 specificity and PD-1 blockade |
| CN113166224A (zh) | 2018-11-27 | 2021-07-23 | 杜克大学 | 用于治疗ebv相关性癌症的抗lmp2 tcr-t细胞疗法 |
| KR20210144739A (ko) * | 2019-03-04 | 2021-11-30 | 유니버시티 헬스 네트워크 | T 세포 수용체 및 이의 사용 방법 |
| EP3714941A1 (en) | 2019-03-27 | 2020-09-30 | Medigene Immunotherapies GmbH | Mage-a4 tcrs |
| WO2020214957A1 (en) | 2019-04-19 | 2020-10-22 | Tcrcure Biopharma Corp. | Anti-pd-1 antibodies and uses thereof |
| AU2020267641A1 (en) * | 2019-05-08 | 2022-01-06 | Medigene Immunotherapies Gmbh | Engineered T cells |
| GB201915359D0 (en) * | 2019-10-23 | 2019-12-04 | Ucl Business Ltd | Engineered regulatory t cell |
| CN113072635B (zh) * | 2020-01-06 | 2023-08-25 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv抗原的t细胞受体及其编码序列 |
| WO2021155518A1 (en) * | 2020-02-05 | 2021-08-12 | Tcrcure Biopharma Corp | Anti-hpv t cell receptors and engineered cells |
| CN113321726B (zh) * | 2020-02-28 | 2024-05-28 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv的t细胞受体 |
| WO2021254458A1 (zh) * | 2020-06-17 | 2021-12-23 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv抗原的高亲和力t细胞受体 |
| WO2022060904A1 (en) | 2020-09-16 | 2022-03-24 | Obsidian Therapeutics, Inc. | Compositions and methods for expression of t-cell receptors with small molecule-regulated cd40l in t cells |
| AU2021351710A1 (en) * | 2020-10-02 | 2023-06-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hla class ii-restricted dq t cell receptors against ras with g13d mutation |
| KR20230104220A (ko) * | 2020-11-05 | 2023-07-07 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | Egfr 항원을 표적화하는 조작된 t 세포 수용체 및 사용 방법 |
| WO2022099032A1 (en) * | 2020-11-06 | 2022-05-12 | Bioventures, Llc | T cells and bifunctional protein against human papillomavirus |
| CN114539385A (zh) * | 2020-11-26 | 2022-05-27 | 香雪生命科学技术（广东）有限公司 | 一种识别hpv抗原的tcr |
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- 2017-10-03 EP EP17787729.7A patent/EP3519433A1/en not_active Withdrawn
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116157528A (zh) * | 2021-09-07 | 2023-05-23 | 北京可瑞生物科技有限公司 | 抗原结合蛋白及其用途 |
| CN116157528B (zh) * | 2021-09-07 | 2025-07-22 | 北京可瑞生物科技有限公司 | 抗原结合蛋白及其用途 |
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| WO2018067618A1 (en) | 2018-04-12 |
| JP2019536437A (ja) | 2019-12-19 |
| EP3519433A1 (en) | 2019-08-07 |
| US11072660B2 (en) | 2021-07-27 |
| US20210363258A1 (en) | 2021-11-25 |
| CN110139873A (zh) | 2019-08-16 |
| MX2019003768A (es) | 2019-06-24 |
| KR20190062505A (ko) | 2019-06-05 |
| US20190225692A1 (en) | 2019-07-25 |
| AU2017338827B2 (en) | 2023-08-31 |
| MA46354A (fr) | 2019-08-07 |
| AU2017338827A1 (en) | 2019-03-28 |
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