CA3031247A1 - Methods of and systems for measuring analytes using batch calibratable test strips - Google Patents
Methods of and systems for measuring analytes using batch calibratable test strips Download PDFInfo
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- CA3031247A1 CA3031247A1 CA3031247A CA3031247A CA3031247A1 CA 3031247 A1 CA3031247 A1 CA 3031247A1 CA 3031247 A CA3031247 A CA 3031247A CA 3031247 A CA3031247 A CA 3031247A CA 3031247 A1 CA3031247 A1 CA 3031247A1
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- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
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- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/552—Glass or silica
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- A—HUMAN NECESSITIES
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- A61B2010/0083—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N2001/2893—Preparing calibration standards
Landscapes
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- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
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| PCT/US2017/042830 WO2018017699A1 (en) | 2016-07-19 | 2017-07-19 | Methods of and systems for measuring analytes using batch calibratable test strips |
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| CA3031247A1 true CA3031247A1 (en) | 2018-01-25 |
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| WO2015191558A1 (en) | 2014-06-09 | 2015-12-17 | Biometry Inc. | Low cost test strip and method to measure analyte |
| US11175268B2 (en) | 2014-06-09 | 2021-11-16 | Biometry Inc. | Mini point of care gas chromatographic test strip and method to measure analytes |
| US11172876B2 (en) * | 2018-03-13 | 2021-11-16 | Charles Gilmartin | Acoustic sensor platform method and apparatus for pain mitigation, apnea detection, aspiration detection and patient communication in anesthesia patients |
| TW202019818A (zh) | 2018-08-14 | 2020-06-01 | 加拿大國家研究委員會 | 用於swcnt電子之靛藍系聚合物 |
| GB201818584D0 (en) * | 2018-11-14 | 2018-12-26 | Exhalation Tech Limited | A device to measure breath humidity |
| US12196727B2 (en) | 2019-01-11 | 2025-01-14 | Eth Zurich | Device and method for detecting an analyte |
| WO2020154740A1 (en) * | 2019-01-25 | 2020-07-30 | Biometry Inc. | System and method for conditioning gas for analysis |
| EP3962358A1 (en) * | 2019-04-29 | 2022-03-09 | Regents of the University of Minnesota | Systems and methods for assessing and treating hemorrhage and other conditions |
| KR102795331B1 (ko) | 2019-08-20 | 2025-04-11 | 삼성전자주식회사 | 가스 농도 측정 장치 및 방법 |
| CN110487872B (zh) * | 2019-09-09 | 2021-05-07 | 北京大学 | 一种基于压舌板的电化学生物传感器 |
| US20210393163A1 (en) * | 2020-06-09 | 2021-12-23 | Graham Biosciences Llc | Device and methods for collecting and processing analytes in air/breath |
| WO2022094576A1 (en) * | 2020-10-29 | 2022-05-05 | Telophase Corporation | Rapid test breathalyzer and methods of use thereof |
| EP4236788B1 (en) | 2020-10-29 | 2025-07-23 | Telophase Corporation | Rapid test breathalyzer |
| US20220134030A1 (en) * | 2020-11-02 | 2022-05-05 | Covidien Lp | Pathogen sensing adaptors for use in breathing circuits |
| CN114002423A (zh) * | 2021-12-31 | 2022-02-01 | 深圳市帝迈生物技术有限公司 | 一种样本分析仪及其检测方法 |
| CN114895015A (zh) * | 2022-03-30 | 2022-08-12 | 新绎健康科技有限公司 | 口气成分多指标检测的自动分配装置及方法 |
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| WO2025184271A1 (en) * | 2024-03-01 | 2025-09-04 | Consumer Safety Technology, Llc | Thermal desorption system for substance detection |
Family Cites Families (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4802487A (en) | 1987-03-26 | 1989-02-07 | Washington Research Foundation | Endoscopically deliverable ultrasound imaging system |
| DE3811713A1 (de) | 1988-04-08 | 1989-10-19 | Bosch Gmbh Robert | Planare polarographische sonde zur bestimmung des (lambda)-wertes von gasgemischen |
| GB8927567D0 (en) | 1989-12-06 | 1990-02-07 | Gen Electric Co Plc | Detection of chemicals |
| JP3040867B2 (ja) | 1991-12-27 | 2000-05-15 | リコーエレメックス株式会社 | 多用途センサ |
| JP2834962B2 (ja) | 1993-04-01 | 1998-12-14 | 三菱電機株式会社 | ガスセンサ |
| US5698083A (en) | 1995-08-18 | 1997-12-16 | Regents Of The University Of California | Chemiresistor urea sensor |
| DE19612680C2 (de) * | 1996-03-29 | 2000-02-03 | Inst Chemo Biosensorik | Kationselektiver Sensor |
| US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
| US6612306B1 (en) | 1999-10-13 | 2003-09-02 | Healthetech, Inc. | Respiratory nitric oxide meter |
| JP2002357589A (ja) | 2001-03-30 | 2002-12-13 | Ngk Spark Plug Co Ltd | ガスセンサ素子及びガスセンサ |
| DE10121262A1 (de) | 2001-04-30 | 2002-11-14 | Siemens Ag | Vorrichtung zur quantitativen Messung von Stickoxiden in der Ausatemluft und Verwendung |
| US6638416B2 (en) | 2001-09-24 | 2003-10-28 | Delphi Technologies, Inc. | Hydrogen sensing process |
| US7956525B2 (en) | 2003-05-16 | 2011-06-07 | Nanomix, Inc. | Flexible nanostructure electronic devices |
| US7179421B1 (en) | 2002-01-24 | 2007-02-20 | Sandia Corporation | Multi-pin chemiresistors for microchemical sensors |
| US7189360B1 (en) | 2002-01-24 | 2007-03-13 | Sandia Corporation | Circular chemiresistors for microchemical sensors |
| US6905655B2 (en) | 2002-03-15 | 2005-06-14 | Nanomix, Inc. | Modification of selectivity for sensing for nanostructure device arrays |
| US20070048180A1 (en) | 2002-09-05 | 2007-03-01 | Gabriel Jean-Christophe P | Nanoelectronic breath analyzer and asthma monitor |
| US7948041B2 (en) | 2005-05-19 | 2011-05-24 | Nanomix, Inc. | Sensor having a thin-film inhibition layer |
| US9237865B2 (en) | 2002-10-18 | 2016-01-19 | Medtronic Minimed, Inc. | Analyte sensors and methods for making and using them |
| WO2005069737A2 (en) * | 2004-01-27 | 2005-08-04 | Ramot At Tel Aviv University Ltd. | Method and system for detecting analytes |
| WO2005082934A2 (en) | 2004-02-20 | 2005-09-09 | Five Prime Therapeutics, Inc. | Novel apo2l and il-24 polypeptides, polynucleotides, and methods of their use |
| US20070264277A1 (en) | 2004-07-22 | 2007-11-15 | Dirk Behrens | Compositions and Methods of Use for Mgd-Csf in Disease Treatment |
| US20080214917A1 (en) * | 2004-12-30 | 2008-09-04 | Dirk Boecker | Method and apparatus for analyte measurement test time |
| MX2008000574A (es) | 2005-07-11 | 2008-03-14 | Sanofi Aventis | Nuevos derivados de 2,4-dianilinopirimidinas, la preparacion de los mismos, su uso como medicamentos, composiciones farmaceuticas y, en particular, como inhibidores ikk. |
| WO2008039165A2 (en) | 2005-07-20 | 2008-04-03 | Nanomix, Inc. | Carbon dioxide nanosensor, and respiratory co2 monitors |
| ES2274712B1 (es) | 2005-10-06 | 2008-03-01 | Laboratorios Almirall S.A. | Nuevos derivados imidazopiridina. |
| US20070114130A1 (en) | 2005-11-18 | 2007-05-24 | Lankheet Earl W | Gas sensors and methods of manufacture |
| EP1790977A1 (en) | 2005-11-23 | 2007-05-30 | SONY DEUTSCHLAND GmbH | Nanoparticle/nanofiber based chemical sensor, arrays of such sensors, uses and method of fabrication thereof, and method of detecting an analyte |
| WO2007064912A2 (en) | 2005-12-02 | 2007-06-07 | Elan Pharma International Limited | Mometasone compositions and methods of making and using the same |
| EP2029013A4 (en) | 2006-05-18 | 2011-09-28 | Nanomix Inc | NANOELECTRONIC BREAST ANALYZER AND ASTHMA MONITORING SYSTEM |
| GB0611114D0 (en) | 2006-06-06 | 2006-07-19 | Perkinelmer Ltd | Analysis technique |
| KR101440648B1 (ko) | 2006-10-12 | 2014-09-22 | 넥스테크 머티리얼스, 엘티디. | 수소 민감성 복합 재료, 수소 및 기타 기체 검출용 튜브형 센서 |
| KR100859343B1 (ko) | 2006-10-30 | 2008-09-25 | 염충균 | 기체투과 막분석장치 및 방법 |
| US20100089772A1 (en) | 2006-11-10 | 2010-04-15 | Deshusses Marc A | Nanomaterial-based gas sensors |
| DE102007049715A1 (de) | 2006-12-29 | 2008-07-03 | Robert Bosch Gmbh | Sensorelement mit abgeschirmter Referenzelektrode |
| FR2911137B1 (fr) | 2007-01-05 | 2009-02-20 | Sanofi Aventis Sa | Nouveaux derives de 2,4-dianilinopyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk |
| US20100282245A1 (en) | 2007-01-12 | 2010-11-11 | Alexander Star | Detection of nitric oxide |
| JP2008180529A (ja) | 2007-01-23 | 2008-08-07 | Furukawa Electric Co Ltd:The | ガスセンサ |
| US20100185112A1 (en) * | 2007-06-27 | 2010-07-22 | Koninklijke Philips Electronics N.V. | Device for analysing an inflammatory status of a respiratory system |
| EP2280284A4 (en) | 2008-05-26 | 2014-10-29 | Panasonic Healthcare Co Ltd | Biosensor |
| US8366630B2 (en) | 2008-05-29 | 2013-02-05 | Technion Research And Development Foundation Ltd. | Carbon nanotube structures in sensor apparatuses for analyzing biomarkers in breath samples |
| JP2010025721A (ja) | 2008-07-18 | 2010-02-04 | Sharp Corp | ガスセンシング装置 |
| JP5420204B2 (ja) | 2008-07-18 | 2014-02-19 | 株式会社船井電機新応用技術研究所 | 携帯型の物質検出装置 |
| US9011670B2 (en) | 2008-08-14 | 2015-04-21 | The Charles Stark Draper Laboratory, Inc. | Three-dimensional metal ion sensor arrays on printed circuit boards |
| JP5422938B2 (ja) * | 2008-08-19 | 2014-02-19 | 凸版印刷株式会社 | 流体測定装置 |
| DE102008049768A1 (de) | 2008-09-30 | 2010-04-08 | Siemens Aktiengesellschaft | Nichtverbrauchendes Gas-Konversionsmodul |
| EP2361093A2 (en) | 2008-11-26 | 2011-08-31 | Five Prime Therapeutics, Inc. | Compositions and methods for regulating collagen and smooth muscle actin expression by serpine2 |
| JP4903911B2 (ja) | 2009-03-16 | 2012-03-28 | シャープ株式会社 | 化学物質センシング装置およびそれを備える化学物質センシングシステム |
| DE102009016848B4 (de) * | 2009-04-08 | 2011-12-01 | Siemens Aktiengesellschaft | Gas-Analysegerät mit einer Kombination aus Gasentfeuchter und Gaskonverter |
| US8226825B2 (en) | 2009-04-09 | 2012-07-24 | The United States of America, as represented by the Sectretary of Commerce, The National Institute of Standards and Technology | Recirculating temperature wave focusing chromatography |
| CA2759104C (en) | 2009-04-24 | 2019-01-29 | Iceutica Pty Ltd | Method for improving the dissolution profile of a biologically active material |
| CN102438592B (zh) | 2009-04-24 | 2016-09-14 | 伊休蒂卡有限公司 | 甲氧萘普酸的剂型 |
| WO2010121324A1 (en) | 2009-04-24 | 2010-10-28 | Iceutica Pty Ltd | A novel formulation of metaxalone |
| GB2469803A (en) | 2009-04-27 | 2010-11-03 | Kanichi Rs Ltd | Electrochemical sensor |
| US8845660B2 (en) | 2009-08-06 | 2014-09-30 | Dsm Ip Assets B.V. | Surgical repair article based on HPPE material |
| DE102009029621A1 (de) | 2009-09-21 | 2011-03-24 | Robert Bosch Gmbh | Detektionsvorrichtung und Verfahren zur Detektion eines Gases |
| DE102009043222B4 (de) * | 2009-09-28 | 2018-10-18 | Robert Bosch Gmbh | Vorrichtung und Verfahren zur Messung mindestens eines Gasanalyten in Ausatemluft |
| CN102596030B (zh) * | 2009-11-03 | 2015-12-09 | 皇家飞利浦电子股份有限公司 | 用于测量呼出气中特定气体的水平的设备 |
| EP2322176A1 (en) | 2009-11-11 | 2011-05-18 | Almirall, S.A. | New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives |
| ITRM20110083U1 (it) | 2010-05-13 | 2011-11-14 | De La Cruz Jose Antonio Freire | Piastra per la costruzione di carrelli per aeroplani |
| EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
| US9536720B2 (en) | 2010-10-29 | 2017-01-03 | Atonarp Inc. | Analyzing apparatus |
| DE102011003291B4 (de) | 2011-01-28 | 2021-12-30 | Robert Bosch Gmbh | Betriebsverfahren für einen Gassensor und Gassensor |
| CN102253105B (zh) | 2011-06-15 | 2013-09-25 | 郑州炜盛电子科技有限公司 | 电化学传感器 |
| EP2725974A1 (en) | 2011-06-28 | 2014-05-07 | Fred Hutchinson Cancer Research Center | End-tidal gas monitoring apparatus |
| DE102011080765A1 (de) | 2011-07-08 | 2013-01-10 | Siemens Aktiengesellschaft | Überwachung der Funktionalität eines Konverters eines Atemanalysegerätes |
| EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| EP2592077A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| AU2013227351B2 (en) | 2012-02-28 | 2016-06-16 | Iceutica Holdings Inc. | Inhalable pharmaceutical compositions |
| JP5832479B2 (ja) | 2012-08-09 | 2015-12-16 | 日本特殊陶業株式会社 | ガスセンサ |
| EP2899538B1 (en) | 2012-09-19 | 2016-11-09 | Panasonic Healthcare Holdings Co., Ltd. | Biosensor |
| EP2900132A4 (en) * | 2012-09-28 | 2016-07-06 | Univ Arizona | MOUTHPIECE FOR ACCURATE DETECTION OF EXTRACTED STAIN OXIDE |
| DE102012220598A1 (de) | 2012-11-13 | 2014-05-28 | BSH Bosch und Siemens Hausgeräte GmbH | Überwachungssystem und Verfahren zur Überwachung und Einstellung von Luftparametern in einem Raum, Dunstabzugsvorrichtung zur Verwendung in einem Überwachungssystem |
| EA201500651A1 (ru) | 2012-12-18 | 2015-11-30 | Альмираль, С.А. | НОВЫЕ ПРОИЗВОДНЫЕ ЦИКЛОГЕКСИЛ- И ХИНУКЛИДИНИЛКАРБАМАТА, ОБЛАДАЮЩИЕ АГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К β2 АДРЕНЕРГИЧЕСКОМУ РЕЦЕПТОРУ И АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К МУСКАРИНОВОМУ РЕЦЕПТОРУ М3 |
| DE102013206111A1 (de) * | 2013-04-08 | 2014-10-09 | Robert Bosch Gmbh | Vorrichtung zur kombinierten Atemgasanalyse und Lungenfunktionsprüfung |
| DE102013221061A1 (de) | 2013-10-17 | 2015-04-23 | Robert Bosch Gmbh | Verfahren und Vorrichtung zur Messung der Konzentration von Stickstoffmonoxid in der Atemluft eines Patienten |
| DE102014210574A1 (de) | 2014-06-04 | 2015-12-17 | Robert Bosch Gmbh | Messvorrichtung und Verfahren zur Bestimmung der asthmatisch wirksamen Belastung bei einem Menschen oder Tier |
| WO2015191558A1 (en) * | 2014-06-09 | 2015-12-17 | Biometry Inc. | Low cost test strip and method to measure analyte |
| DE102014219132A1 (de) | 2014-09-23 | 2016-03-24 | Robert Bosch Gmbh | Vorrichtung zur Analyse der Ausatemluft mit einer Gassensoreinrichtung |
| DE102014219161A1 (de) | 2014-09-23 | 2016-03-24 | Robert Bosch Gmbh | Vorrichtung zur Analyse der Ausatemluft und Verwendung der Vorrichtung |
| DE102014219561A1 (de) | 2014-09-26 | 2016-03-31 | Robert Bosch Gmbh | Einrichtung zur Analyse von Substanzen in einer Probe, Atemgasanalysegerät, Kraftstoffsensor und Verfahren |
| ES3033732T3 (en) | 2014-12-24 | 2025-08-07 | Biometry Inc | Method to measure analytes with a gas chromatographic test strip |
| KR101786803B1 (ko) | 2016-05-24 | 2017-11-15 | 연세대학교 산학협력단 | Coffee-Ring Effect를 활용할 수 있는 가스 센서 플랫폼 및 그 제조방법 |
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2017
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| CN114859028A (zh) | 2022-08-05 |
| JP2023171847A (ja) | 2023-12-05 |
| US12038428B2 (en) | 2024-07-16 |
| EP3487407A4 (en) | 2019-11-13 |
| JP7561941B2 (ja) | 2024-10-04 |
| EP3487407A1 (en) | 2019-05-29 |
| US20240402152A1 (en) | 2024-12-05 |
| EP4464772A2 (en) | 2024-11-20 |
| US20220299499A1 (en) | 2022-09-22 |
| NZ750019A (en) | 2025-05-30 |
| EP3487407B1 (en) | 2024-10-02 |
| ES2988367T3 (es) | 2024-11-20 |
| JP7086927B2 (ja) | 2022-06-20 |
| CN109715067A (zh) | 2019-05-03 |
| AU2017300528A1 (en) | 2019-01-31 |
| EP3487407C0 (en) | 2024-10-02 |
| JP2022120051A (ja) | 2022-08-17 |
| WO2018017699A1 (en) | 2018-01-25 |
| JP2019526049A (ja) | 2019-09-12 |
| EP4464772A3 (en) | 2024-12-04 |
| AU2017300528B2 (en) | 2022-04-07 |
| AU2017300528C1 (en) | 2022-10-20 |
| US20200200733A1 (en) | 2020-06-25 |
| JP7358563B2 (ja) | 2023-10-10 |
| US11255840B2 (en) | 2022-02-22 |
| CN109715067B (zh) | 2022-05-17 |
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