CA3027999A1 - Mhc-e restricted epitopes, binding molecules and related methods and uses - Google Patents
Mhc-e restricted epitopes, binding molecules and related methods and uses Download PDFInfo
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- CA3027999A1 CA3027999A1 CA3027999A CA3027999A CA3027999A1 CA 3027999 A1 CA3027999 A1 CA 3027999A1 CA 3027999 A CA3027999 A CA 3027999A CA 3027999 A CA3027999 A CA 3027999A CA 3027999 A1 CA3027999 A1 CA 3027999A1
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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| JP7181517B2 (ja) * | 2018-01-23 | 2022-12-01 | 国立大学法人三重大学 | T細胞レセプター |
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| RU2020135968A (ru) | 2018-04-05 | 2022-05-06 | Джуно Терапьютикс, Инк. | T-клеточные рецепторы и модифицированные клетки, экспрессирующие |
| EP3827021A4 (en) * | 2018-07-23 | 2022-08-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | ANTIBODIES DIRECTED TO A NON-CLASSIC HLA-I/NEOANTIGEN COMPLEX AND THEIR USE |
| EP3896158A4 (en) * | 2018-12-11 | 2022-11-02 | Kyoto University | METHODS OF INDUCING A DELETION IN GENOMIC DNA |
| CN109913414A (zh) * | 2019-03-21 | 2019-06-21 | 吉林省银丰生物工程技术有限公司 | 肝癌afp特异性人工抗原递呈细胞诱导试剂盒 |
| JP7668226B2 (ja) * | 2019-03-30 | 2025-04-24 | ビオンテック ユーエス インコーポレイテッド | T細胞組成物を調製するための組成物および方法、ならびにそれらの使用 |
| TW202115245A (zh) | 2019-06-27 | 2021-04-16 | 丹麥商諾佛 儂迪克股份有限公司 | 安全免疫隱形細胞 |
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| CN110734474B (zh) * | 2019-11-29 | 2021-10-19 | 中山大学 | 一种抗菌肽的筛选方法及其应用 |
| CN115003802B (zh) * | 2020-01-02 | 2024-09-03 | 宁波茂行生物医药科技有限公司 | 一种经修饰的免疫效应细胞及其制备方法 |
| CN111116716B (zh) * | 2020-03-03 | 2022-03-01 | 中国医科大学 | 一种与骨髓瘤细胞高表达抗原hla-e特异性结合的多肽及其用途 |
| US12433954B2 (en) | 2020-05-01 | 2025-10-07 | Massachusetts Institute Of Technology | Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs |
| US20210340524A1 (en) * | 2020-05-01 | 2021-11-04 | Massachusetts Institute Of Technology | Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof |
| US10981996B1 (en) | 2020-06-01 | 2021-04-20 | Abexxa Biologics, Inc. | Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use |
| US11976120B2 (en) | 2020-06-01 | 2024-05-07 | Boehringer Ingelheim International Gmbh | Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use |
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| WO2022047325A1 (en) * | 2020-08-31 | 2022-03-03 | The Trustees Of Columbia University In The City Of New York | Targeting of tgm4 to treat prostate cancer |
| WO2022129472A1 (en) | 2020-12-18 | 2022-06-23 | Novo Nordisk A/S | Safe immuno-stealth cells |
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| EP4323395A4 (en) * | 2021-04-12 | 2025-04-02 | Memorial Sloan Kettering Cancer Center | MANIPULATED HLA MOLECULES FOR T CELL AND NK CELL ACTIVATION AND EXPANSION |
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| ES2894257T3 (es) | 2022-02-14 |
| WO2018005556A1 (en) | 2018-01-04 |
| JP7340638B2 (ja) | 2023-09-07 |
| CN109937364A (zh) | 2019-06-25 |
| MA45491A (fr) | 2019-05-01 |
| EP3992632A1 (en) | 2022-05-04 |
| CN109937364B (zh) | 2022-12-02 |
| US20190324030A1 (en) | 2019-10-24 |
| EP3475706A1 (en) | 2019-05-01 |
| EP3475706B1 (en) | 2021-08-11 |
| JP2022081490A (ja) | 2022-05-31 |
| JP2019520591A (ja) | 2019-07-18 |
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