CA2981715A1 - Chemically modified guide rnas for crispr/cas-mediated gene regulation - Google Patents

Chemically modified guide rnas for crispr/cas-mediated gene regulation Download PDF

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Publication number
CA2981715A1
CA2981715A1 CA2981715A CA2981715A CA2981715A1 CA 2981715 A1 CA2981715 A1 CA 2981715A1 CA 2981715 A CA2981715 A CA 2981715A CA 2981715 A CA2981715 A CA 2981715A CA 2981715 A1 CA2981715 A1 CA 2981715A1
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Canada
Prior art keywords
sgrna
modified
target
cell
nucleotide sequence
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CA2981715A
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English (en)
French (fr)
Inventor
Matthew H. PORTEUS
Ayal HENDEL
Joe Clark
Rasmus O. BAK
Daniel E. Ryan
Douglas J. Dellinger
Robert Kaiser
Joel Myerson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Inc
Leland Stanford Junior University
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Agilent Technologies Inc
Leland Stanford Junior University
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55910340&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2981715(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agilent Technologies Inc, Leland Stanford Junior University filed Critical Agilent Technologies Inc
Publication of CA2981715A1 publication Critical patent/CA2981715A1/en
Pending legal-status Critical Current

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CA2981715A 2015-04-06 2016-04-05 Chemically modified guide rnas for crispr/cas-mediated gene regulation Pending CA2981715A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562143729P 2015-04-06 2015-04-06
US62/143,729 2015-04-06
US201562160545P 2015-05-12 2015-05-12
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CN107787367A (zh) 2018-03-09
EP3280803B1 (en) 2021-05-26
KR20240038141A (ko) 2024-03-22
US11306309B2 (en) 2022-04-19
JP2018513682A (ja) 2018-05-31
US11535846B2 (en) 2022-12-27
US20180119140A1 (en) 2018-05-03
WO2016164356A1 (en) 2016-10-13
US20220195425A1 (en) 2022-06-23
US20220195426A1 (en) 2022-06-23
JP6873911B2 (ja) 2021-05-19
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AU2016246450B2 (en) 2022-03-17
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US20240401034A1 (en) 2024-12-05
KR102888521B1 (ko) 2025-11-19
CN114231527A (zh) 2022-03-25
US20220195427A1 (en) 2022-06-23
AU2022204254A1 (en) 2022-07-07

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