CA2945900C - Method of forming methyl penam derivatives - Google Patents

Method of forming methyl penam derivatives Download PDF

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Publication number
CA2945900C
CA2945900C CA2945900A CA2945900A CA2945900C CA 2945900 C CA2945900 C CA 2945900C CA 2945900 A CA2945900 A CA 2945900A CA 2945900 A CA2945900 A CA 2945900A CA 2945900 C CA2945900 C CA 2945900C
Authority
CA
Canada
Prior art keywords
formula
compound
alkyl
independently selected
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2945900A
Other languages
English (en)
French (fr)
Other versions
CA2945900A1 (en
Inventor
Andrea FAINI
Marco Forzatti
Giovanni Fogliato
Stefano Biondi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allecra Therapeutics SAS
Original Assignee
Allecra Therapeutics SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allecra Therapeutics SAS filed Critical Allecra Therapeutics SAS
Publication of CA2945900A1 publication Critical patent/CA2945900A1/en
Application granted granted Critical
Publication of CA2945900C publication Critical patent/CA2945900C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/87—Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Feed For Specific Animals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
CA2945900A 2014-05-15 2015-05-14 Method of forming methyl penam derivatives Active CA2945900C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1408649.0A GB201408649D0 (en) 2014-05-15 2014-05-15 Method
GB1408649.0 2014-05-15
PCT/EP2015/060733 WO2015173378A2 (en) 2014-05-15 2015-05-14 Method

Publications (2)

Publication Number Publication Date
CA2945900A1 CA2945900A1 (en) 2015-11-19
CA2945900C true CA2945900C (en) 2023-01-24

Family

ID=51134924

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2945900A Active CA2945900C (en) 2014-05-15 2015-05-14 Method of forming methyl penam derivatives

Country Status (29)

Country Link
US (1) US9963465B2 (enExample)
EP (3) EP3143028B1 (enExample)
JP (1) JP6613303B2 (enExample)
KR (1) KR102329186B1 (enExample)
CN (1) CN106459086B (enExample)
AU (1) AU2015261416B2 (enExample)
BR (1) BR112016026074B1 (enExample)
CA (1) CA2945900C (enExample)
CL (2) CL2016002880A1 (enExample)
CR (1) CR20160580A (enExample)
CY (2) CY1120957T1 (enExample)
DK (2) DK3143028T3 (enExample)
EA (2) EA201991629A3 (enExample)
EC (1) ECSP16085143A (enExample)
ES (2) ES2725675T3 (enExample)
GB (1) GB201408649D0 (enExample)
HR (2) HRP20182065T1 (enExample)
HU (1) HUE044511T2 (enExample)
IL (1) IL248834B (enExample)
LT (2) LT3231806T (enExample)
MX (1) MX378875B (enExample)
PE (1) PE20161433A1 (enExample)
PL (2) PL3143028T3 (enExample)
PT (2) PT3231806T (enExample)
RS (2) RS58748B1 (enExample)
SG (1) SG11201609494YA (enExample)
SI (2) SI3231806T1 (enExample)
TR (1) TR201906867T4 (enExample)
WO (1) WO2015173378A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201319776D0 (en) * 2013-11-08 2013-12-25 Allecra Therapeutics Sas Compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1319776A (en) 1969-07-15 1973-06-06 Yorkshire Chemicals Ltd Basic dyes
WO2008010048A2 (en) * 2006-07-12 2008-01-24 Orchid Chemicals & Pharmaceuticals Limited Novel 2-substituted methyl penam derivatives
EA030662B1 (ru) * 2010-11-25 2018-09-28 Аллекра Терапойтикс Гмбх β-ЛАКТАМОВЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ β-ЛАКТАМАЗЫ И ИХ ПРИМЕНЕНИЕ
KR20120067257A (ko) * 2010-12-15 2012-06-25 서강대학교산학협력단 3-메틸-1,4-치환된 1,2,3-트라이아졸륨 기반의 이온성 액체 및 그의 제조방법과 응용

Also Published As

Publication number Publication date
ES2699644T3 (es) 2019-02-12
CA2945900A1 (en) 2015-11-19
CN106459086A (zh) 2017-02-22
SG11201609494YA (en) 2016-12-29
PL3143028T3 (pl) 2019-04-30
CL2016002880A1 (es) 2017-06-16
EA201692306A1 (ru) 2017-05-31
JP6613303B2 (ja) 2019-11-27
EA201991629A3 (ru) 2020-02-28
EP3231806A1 (en) 2017-10-18
IL248834B (en) 2019-05-30
WO2015173378A2 (en) 2015-11-19
PT3143028T (pt) 2018-12-17
EP3231806B1 (en) 2019-02-13
PE20161433A1 (es) 2017-01-18
KR102329186B1 (ko) 2021-11-22
AU2015261416B2 (en) 2019-07-11
US9963465B2 (en) 2018-05-08
HRP20190830T1 (hr) 2019-06-28
HRP20182065T1 (hr) 2019-02-08
GB201408649D0 (en) 2014-07-02
EP3441395A1 (en) 2019-02-13
BR112016026074A8 (pt) 2021-03-30
CR20160580A (es) 2017-05-09
HUE044511T2 (hu) 2019-10-28
CY1121756T1 (el) 2020-07-31
MX378875B (es) 2025-03-11
EP3143028B1 (en) 2018-09-26
NZ725121A (en) 2023-09-29
ES2725675T3 (es) 2019-09-26
WO2015173378A3 (en) 2016-01-14
EA201991629A2 (ru) 2019-12-30
TR201906867T4 (tr) 2019-05-21
KR20170002466A (ko) 2017-01-06
US20170101421A1 (en) 2017-04-13
DK3231806T3 (da) 2019-05-20
JP2017515907A (ja) 2017-06-15
RS58430B1 (sr) 2019-04-30
RS58748B1 (sr) 2019-06-28
LT3143028T (lt) 2018-12-27
PT3231806T (pt) 2019-05-30
LT3231806T (lt) 2019-05-27
EA033494B1 (ru) 2019-10-31
EP3143028A2 (en) 2017-03-22
CL2018001961A1 (es) 2018-08-31
CN106459086B (zh) 2018-11-13
AU2015261416A1 (en) 2016-11-10
ECSP16085143A (es) 2017-05-31
SI3143028T1 (sl) 2019-01-31
PL3231806T3 (pl) 2019-08-30
MX2016014644A (es) 2017-02-23
BR112016026074B1 (pt) 2023-01-03
DK3143028T3 (da) 2019-01-02
SI3231806T1 (sl) 2019-06-28
CY1120957T1 (el) 2019-12-11
IL248834A0 (en) 2017-01-31

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