EA201991629A3 - Способ - Google Patents

Способ

Info

Publication number
EA201991629A3
EA201991629A3 EA201991629A EA201991629A EA201991629A3 EA 201991629 A3 EA201991629 A3 EA 201991629A3 EA 201991629 A EA201991629 A EA 201991629A EA 201991629 A EA201991629 A EA 201991629A EA 201991629 A3 EA201991629 A3 EA 201991629A3
Authority
EA
Eurasian Patent Office
Prior art keywords
alkyl
formula
alkynyl
alkenyl
halogen
Prior art date
Application number
EA201991629A
Other languages
English (en)
Other versions
EA201991629A2 (ru
Inventor
Андреа Файни
Марко Форцатти
Джованни Фольято
Стефано Бьонди
Original Assignee
Аллекра Терапьютикс Сас
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аллекра Терапьютикс Сас filed Critical Аллекра Терапьютикс Сас
Publication of EA201991629A2 publication Critical patent/EA201991629A2/ru
Publication of EA201991629A3 publication Critical patent/EA201991629A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/87—Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Feed For Specific Animals (AREA)
  • Steroid Compounds (AREA)

Abstract

Способ получения соединений формулы (IIIa), где Rв каждом случае независимо выбран из H, галогена, амино, Cалкила, Cалкенила и Cалкинила; Rв каждом случае независимо выбран из H, галогена, амино, Cалкила, Cалкенила и Cалкинила; Rозначает Cалкил; Rозначает Cфторалкил; a PG означает защитную группу; который включает стадию взаимодействия соединения формулы (IIa) с соединением формулы (VIII).
EA201991629A 2014-05-15 2015-05-14 Способ EA201991629A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1408649.0A GB201408649D0 (en) 2014-05-15 2014-05-15 Method

Publications (2)

Publication Number Publication Date
EA201991629A2 EA201991629A2 (ru) 2019-12-30
EA201991629A3 true EA201991629A3 (ru) 2020-02-28

Family

ID=51134924

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201692306A EA033494B1 (ru) 2014-05-15 2015-05-14 Способ получения метиловых производных пенама
EA201991629A EA201991629A3 (ru) 2014-05-15 2015-05-14 Способ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201692306A EA033494B1 (ru) 2014-05-15 2015-05-14 Способ получения метиловых производных пенама

Country Status (29)

Country Link
US (1) US9963465B2 (ru)
EP (3) EP3143028B1 (ru)
JP (1) JP6613303B2 (ru)
KR (1) KR102329186B1 (ru)
CN (1) CN106459086B (ru)
AU (1) AU2015261416B2 (ru)
BR (1) BR112016026074B1 (ru)
CA (1) CA2945900C (ru)
CL (2) CL2016002880A1 (ru)
CR (1) CR20160580A (ru)
CY (2) CY1120957T1 (ru)
DK (2) DK3231806T3 (ru)
EA (2) EA033494B1 (ru)
EC (1) ECSP16085143A (ru)
ES (2) ES2699644T3 (ru)
GB (1) GB201408649D0 (ru)
HR (2) HRP20182065T1 (ru)
HU (1) HUE044511T2 (ru)
IL (1) IL248834B (ru)
LT (2) LT3143028T (ru)
MX (1) MX2016014644A (ru)
PE (1) PE20161433A1 (ru)
PL (2) PL3143028T3 (ru)
PT (2) PT3143028T (ru)
RS (2) RS58430B1 (ru)
SG (1) SG11201609494YA (ru)
SI (2) SI3143028T1 (ru)
TR (1) TR201906867T4 (ru)
WO (1) WO2015173378A2 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201319776D0 (en) * 2013-11-08 2013-12-25 Allecra Therapeutics Sas Compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1319776A (en) 1969-07-15 1973-06-06 Yorkshire Chemicals Ltd Basic dyes
PT2046802E (pt) * 2006-07-12 2013-09-12 Allecra Therapeutics Gmbh Derivados de penamo 2-substituídos com metilo
EA030662B1 (ru) * 2010-11-25 2018-09-28 Аллекра Терапойтикс Гмбх β-ЛАКТАМОВЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ β-ЛАКТАМАЗЫ И ИХ ПРИМЕНЕНИЕ
KR20120067257A (ko) * 2010-12-15 2012-06-25 서강대학교산학협력단 3-메틸-1,4-치환된 1,2,3-트라이아졸륨 기반의 이온성 액체 및 그의 제조방법과 응용

Also Published As

Publication number Publication date
WO2015173378A3 (en) 2016-01-14
AU2015261416A1 (en) 2016-11-10
HRP20182065T1 (hr) 2019-02-08
CA2945900C (en) 2023-01-24
PL3143028T3 (pl) 2019-04-30
CN106459086A (zh) 2017-02-22
DK3143028T3 (da) 2019-01-02
EA201991629A2 (ru) 2019-12-30
WO2015173378A2 (en) 2015-11-19
KR102329186B1 (ko) 2021-11-22
PT3231806T (pt) 2019-05-30
CY1120957T1 (el) 2019-12-11
DK3231806T3 (da) 2019-05-20
ECSP16085143A (es) 2017-05-31
US20170101421A1 (en) 2017-04-13
LT3231806T (lt) 2019-05-27
BR112016026074A8 (pt) 2021-03-30
US9963465B2 (en) 2018-05-08
ES2699644T3 (es) 2019-02-12
CA2945900A1 (en) 2015-11-19
HRP20190830T1 (hr) 2019-06-28
IL248834A0 (en) 2017-01-31
EP3231806A1 (en) 2017-10-18
PT3143028T (pt) 2018-12-17
JP6613303B2 (ja) 2019-11-27
EP3231806B1 (en) 2019-02-13
PL3231806T3 (pl) 2019-08-30
EP3441395A1 (en) 2019-02-13
SI3143028T1 (sl) 2019-01-31
AU2015261416B2 (en) 2019-07-11
RS58430B1 (sr) 2019-04-30
NZ725121A (en) 2023-09-29
MX2016014644A (es) 2017-02-23
RS58748B1 (sr) 2019-06-28
CN106459086B (zh) 2018-11-13
EA201692306A1 (ru) 2017-05-31
SI3231806T1 (sl) 2019-06-28
EA033494B1 (ru) 2019-10-31
CR20160580A (es) 2017-05-09
CL2016002880A1 (es) 2017-06-16
LT3143028T (lt) 2018-12-27
EP3143028B1 (en) 2018-09-26
HUE044511T2 (hu) 2019-10-28
PE20161433A1 (es) 2017-01-18
TR201906867T4 (tr) 2019-05-21
CY1121756T1 (el) 2020-07-31
JP2017515907A (ja) 2017-06-15
BR112016026074B1 (pt) 2023-01-03
SG11201609494YA (en) 2016-12-29
KR20170002466A (ko) 2017-01-06
IL248834B (en) 2019-05-30
EP3143028A2 (en) 2017-03-22
ES2725675T3 (es) 2019-09-26
CL2018001961A1 (es) 2018-08-31
GB201408649D0 (en) 2014-07-02

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