CR20160580A - Métodos de formación de derivados del metil - Google Patents
Métodos de formación de derivados del metilInfo
- Publication number
- CR20160580A CR20160580A CR20160580A CR20160580A CR20160580A CR 20160580 A CR20160580 A CR 20160580A CR 20160580 A CR20160580 A CR 20160580A CR 20160580 A CR20160580 A CR 20160580A CR 20160580 A CR20160580 A CR 20160580A
- Authority
- CR
- Costa Rica
- Prior art keywords
- metil
- training
- derivatives
- methods
- alkyl
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000003709 fluoroalkyl group Chemical group 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/87—Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Feed For Specific Animals (AREA)
- Steroid Compounds (AREA)
Abstract
Un método de formación de un compuesto de fórmula (IIIa); en donde:R1 en cada ocurrencia se selecciona independientemente de H, halógeno, amino, alquilo de C1-5, alquenilo de C1-5 y alquinilo de C1-5;R2 en cada ocurrencia se selecciona independientemente de H, halógeno, amino, alquilo de C1-5, alquenilo de C1-5 y alquinilo de C1-5;R4 es alquilo de C1-5; yR6 es un fluoroalquilo de C1-5; yPG es un grupo protector; el método comprende el paso de hacer reaccionar un compuesto de fórmula (IIa) con un compuesto de fórmula (VIII).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1408649.0A GB201408649D0 (en) | 2014-05-15 | 2014-05-15 | Method |
| PCT/EP2015/060733 WO2015173378A2 (en) | 2014-05-15 | 2015-05-14 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20160580A true CR20160580A (es) | 2017-05-09 |
Family
ID=51134924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20160580A CR20160580A (es) | 2014-05-15 | 2015-05-14 | Métodos de formación de derivados del metil |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9963465B2 (es) |
| EP (3) | EP3143028B1 (es) |
| JP (1) | JP6613303B2 (es) |
| KR (1) | KR102329186B1 (es) |
| CN (1) | CN106459086B (es) |
| AU (1) | AU2015261416B2 (es) |
| BR (1) | BR112016026074B1 (es) |
| CA (1) | CA2945900C (es) |
| CL (2) | CL2016002880A1 (es) |
| CR (1) | CR20160580A (es) |
| CY (2) | CY1120957T1 (es) |
| DK (2) | DK3231806T3 (es) |
| EA (2) | EA033494B1 (es) |
| EC (1) | ECSP16085143A (es) |
| ES (2) | ES2699644T3 (es) |
| GB (1) | GB201408649D0 (es) |
| HR (2) | HRP20182065T1 (es) |
| HU (1) | HUE044511T2 (es) |
| IL (1) | IL248834B (es) |
| LT (2) | LT3143028T (es) |
| MX (1) | MX2016014644A (es) |
| PE (1) | PE20161433A1 (es) |
| PL (2) | PL3143028T3 (es) |
| PT (2) | PT3143028T (es) |
| RS (2) | RS58430B1 (es) |
| SG (1) | SG11201609494YA (es) |
| SI (2) | SI3143028T1 (es) |
| TR (1) | TR201906867T4 (es) |
| WO (1) | WO2015173378A2 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201319776D0 (en) * | 2013-11-08 | 2013-12-25 | Allecra Therapeutics Sas | Compound |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1319776A (en) | 1969-07-15 | 1973-06-06 | Yorkshire Chemicals Ltd | Basic dyes |
| PT2046802E (pt) * | 2006-07-12 | 2013-09-12 | Allecra Therapeutics Gmbh | Derivados de penamo 2-substituídos com metilo |
| EA030662B1 (ru) * | 2010-11-25 | 2018-09-28 | Аллекра Терапойтикс Гмбх | β-ЛАКТАМОВЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ β-ЛАКТАМАЗЫ И ИХ ПРИМЕНЕНИЕ |
| KR20120067257A (ko) * | 2010-12-15 | 2012-06-25 | 서강대학교산학협력단 | 3-메틸-1,4-치환된 1,2,3-트라이아졸륨 기반의 이온성 액체 및 그의 제조방법과 응용 |
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2014
- 2014-05-15 GB GBGB1408649.0A patent/GB201408649D0/en not_active Ceased
-
2015
- 2015-05-14 WO PCT/EP2015/060733 patent/WO2015173378A2/en active Application Filing
- 2015-05-14 TR TR2019/06867T patent/TR201906867T4/tr unknown
- 2015-05-14 KR KR1020167032608A patent/KR102329186B1/ko active IP Right Grant
- 2015-05-14 CR CR20160580A patent/CR20160580A/es unknown
- 2015-05-14 SI SI201530509T patent/SI3143028T1/sl unknown
- 2015-05-14 CN CN201580024639.6A patent/CN106459086B/zh active Active
- 2015-05-14 EP EP15726552.1A patent/EP3143028B1/en active Active
- 2015-05-14 ES ES15726552T patent/ES2699644T3/es active Active
- 2015-05-14 PT PT15726552T patent/PT3143028T/pt unknown
- 2015-05-14 CA CA2945900A patent/CA2945900C/en active Active
- 2015-05-14 MX MX2016014644A patent/MX2016014644A/es unknown
- 2015-05-14 PE PE2016002171A patent/PE20161433A1/es unknown
- 2015-05-14 BR BR112016026074-0A patent/BR112016026074B1/pt active IP Right Grant
- 2015-05-14 AU AU2015261416A patent/AU2015261416B2/en active Active
- 2015-05-14 LT LTEP15726552.1T patent/LT3143028T/lt unknown
- 2015-05-14 RS RS20181383A patent/RS58430B1/sr unknown
- 2015-05-14 EA EA201692306A patent/EA033494B1/ru unknown
- 2015-05-14 EP EP18195989.1A patent/EP3441395A1/en not_active Withdrawn
- 2015-05-14 HU HUE17168966 patent/HUE044511T2/hu unknown
- 2015-05-14 PL PL15726552T patent/PL3143028T3/pl unknown
- 2015-05-14 EP EP17168966.4A patent/EP3231806B1/en active Active
- 2015-05-14 PT PT17168966T patent/PT3231806T/pt unknown
- 2015-05-14 EA EA201991629A patent/EA201991629A3/ru unknown
- 2015-05-14 SI SI201530738T patent/SI3231806T1/sl unknown
- 2015-05-14 SG SG11201609494YA patent/SG11201609494YA/en unknown
- 2015-05-14 US US15/311,146 patent/US9963465B2/en active Active
- 2015-05-14 LT LTEP17168966.4T patent/LT3231806T/lt unknown
- 2015-05-14 JP JP2017512434A patent/JP6613303B2/ja active Active
- 2015-05-14 ES ES17168966T patent/ES2725675T3/es active Active
- 2015-05-14 DK DK17168966.4T patent/DK3231806T3/da active
- 2015-05-14 PL PL17168966T patent/PL3231806T3/pl unknown
- 2015-05-14 DK DK15726552.1T patent/DK3143028T3/da active
- 2015-05-14 RS RS20190558A patent/RS58748B1/sr unknown
-
2016
- 2016-10-29 EC ECIEPI201685143A patent/ECSP16085143A/es unknown
- 2016-11-08 IL IL248834A patent/IL248834B/en active IP Right Grant
- 2016-11-11 CL CL2016002880A patent/CL2016002880A1/es unknown
-
2018
- 2018-07-19 CL CL2018001961A patent/CL2018001961A1/es unknown
- 2018-12-05 CY CY181101299T patent/CY1120957T1/el unknown
- 2018-12-06 HR HRP20182065TT patent/HRP20182065T1/hr unknown
-
2019
- 2019-05-06 HR HRP20190830TT patent/HRP20190830T1/hr unknown
- 2019-05-09 CY CY20191100501T patent/CY1121756T1/el unknown
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