CA2926154C - New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same - Google Patents

New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same Download PDF

Info

Publication number
CA2926154C
CA2926154C CA2926154A CA2926154A CA2926154C CA 2926154 C CA2926154 C CA 2926154C CA 2926154 A CA2926154 A CA 2926154A CA 2926154 A CA2926154 A CA 2926154A CA 2926154 C CA2926154 C CA 2926154C
Authority
CA
Canada
Prior art keywords
poly
ethylene imine
based copolymer
genetic material
bonding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2926154A
Other languages
English (en)
French (fr)
Other versions
CA2926154A1 (en
Inventor
Christoph Englert
Lutz Tauhardt
Michael Gottschaldt
Ulrich S. Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smartdyelivery GmbH
Original Assignee
Smartdyelivery GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smartdyelivery GmbH filed Critical Smartdyelivery GmbH
Publication of CA2926154A1 publication Critical patent/CA2926154A1/en
Application granted granted Critical
Publication of CA2926154C publication Critical patent/CA2926154C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0233Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • C08G73/0213Preparatory process
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G81/00Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2926154A 2013-10-02 2014-10-02 New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same Active CA2926154C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102013016750.7A DE102013016750A1 (de) 2013-10-02 2013-10-02 Neue Poly(ethylenimin) basierte Copolymere zur Anbindung und Freisetzung von genetischem Material, insbesondere von DNA/RNA, sowie Verfahren zu deren Herstellung und Verwendung
DE102013016750.7 2013-10-02
PCT/DE2014/000500 WO2015048940A1 (de) 2013-10-02 2014-10-02 Neue poly(ethylenimin) basierte copolymere zur anbindung und freisetzung von genetischem material, insbesondere von dna/rna, sowie verfahren zu deren herstellung und verwendung

Publications (2)

Publication Number Publication Date
CA2926154A1 CA2926154A1 (en) 2015-04-09
CA2926154C true CA2926154C (en) 2022-08-30

Family

ID=51986963

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2926154A Active CA2926154C (en) 2013-10-02 2014-10-02 New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same

Country Status (10)

Country Link
US (1) US10131747B2 (https=)
EP (1) EP3052545B1 (https=)
JP (1) JP6431533B2 (https=)
CN (1) CN105683256B (https=)
CA (1) CA2926154C (https=)
DE (1) DE102013016750A1 (https=)
DK (1) DK3052545T3 (https=)
ES (1) ES2691094T3 (https=)
HU (1) HUE040402T2 (https=)
WO (1) WO2015048940A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101892955B1 (ko) 2017-01-25 2018-08-29 국방과학연구소 치환된 Poly[2-(3-butenyl)-2-oxazoline] 및 Nylon-6,6를 포함하는 섬유 및 그 제조방법
EP4229115A1 (en) * 2020-10-19 2023-08-23 Universiteit Gent Cross-linkable allylamido polymers

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3251778A (en) * 1960-08-04 1966-05-17 Petrolite Corp Process of preventing scale
DE19726186A1 (de) * 1997-06-20 1998-12-24 Boehringer Ingelheim Int Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen
DE10029028A1 (de) * 2000-06-13 2001-12-20 Basf Ag Verwendung von acylierten Polyaminen zur Modifizierung von Oberflächen
DE20122328U1 (de) * 2001-12-07 2006-02-09 Sandler Ag Neue modifizierte Poly-2-oxazoline
JP4368183B2 (ja) * 2003-11-06 2009-11-18 財団法人川村理化学研究所 ポリイオン会合体およびポリイオン会合体からなる生体物質キャリアー
US20050238825A1 (en) * 2004-04-26 2005-10-27 Isp Investments Inc. Crosslinked polymeric composition
DE102005039154A1 (de) * 2005-08-17 2007-03-01 GÖPFERICH, Achim, Prof. Dr. Bioabbaubare Polymere für den Transport von Nukleinsäuren in Zellen
US20070231392A1 (en) * 2006-01-23 2007-10-04 Ernst Wagner CHEMICALLY MODIFIED POLYCATION POLYMER FOR siRNA DELIVERY
CA2711455C (en) 2008-02-13 2016-06-07 Hyperbranch Medical Technology, Inc. Crosslinked polyalkyleneimine hydrogels with tunable degradation rates
JP5642673B2 (ja) * 2008-07-10 2014-12-17 セリナ・セラピユーテイツクス・インコーポレーテツド 不活性末端基を有するポリオキサゾリン類、保護された開始基から調製されるポリオキサゾリン類及び関連化合物
CN101768276B (zh) * 2008-12-26 2011-11-30 中国科学技术大学 聚乙二醇单甲醚-聚己内酯-聚乙烯亚胺三嵌段共聚物及其应用
RU2013103347A (ru) * 2010-06-25 2014-07-27 Торэй Индастриз, Инк. Водорастворимый полимер и водорастворимый комплекс наночастиц
RU2593755C2 (ru) * 2011-01-04 2016-08-10 Бендер Аналитикал Холдинг Б.В. Сшитые полимеры и имплантаты, произведенные из электрофильно активированного полиоксазолина
EP2683420B1 (en) * 2011-03-11 2018-05-23 W. L. Gore & Associates, Inc. Improvements to immobilised biological entities
AT511386B1 (de) 2011-05-03 2013-03-15 Ke Kelit Kunststoffwerk Gmbh Kontaktbiozid
US9416228B2 (en) * 2012-03-16 2016-08-16 Bender Analytical Holding B.V. Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline

Also Published As

Publication number Publication date
HUE040402T2 (hu) 2019-03-28
US10131747B2 (en) 2018-11-20
JP6431533B2 (ja) 2018-11-28
CA2926154A1 (en) 2015-04-09
EP3052545B1 (de) 2018-07-25
CN105683256B (zh) 2018-02-23
CN105683256A (zh) 2016-06-15
DK3052545T3 (en) 2018-10-29
ES2691094T3 (es) 2018-11-23
JP2016533409A (ja) 2016-10-27
DE102013016750A1 (de) 2015-04-02
US20170166697A1 (en) 2017-06-15
WO2015048940A1 (de) 2015-04-09
EP3052545A1 (de) 2016-08-10

Similar Documents

Publication Publication Date Title
Roy et al. Synthesis of natural–synthetic hybrid materials from cellulose via the RAFT process
KR101677515B1 (ko) 고분자 그라프트 나노실리카 및 그 제조방법
CN108026217B (zh) 聚合物颗粒
CN102884128A (zh) 基于纳米晶纤维素(ncc)的热塑性纳米复合材料
Ates et al. Functional Brush‐Decorated Poly (globalide) Films by ARGET‐ATRP for Bioconjugation
Hemmati et al. Synthesis and characterization of pH-responsive nanohydrogels as biocompatible drug carriers based on chemically modified tragacanth gum polysaccharide
Thies Reversible immobilization onto PEG-based emulsion-templated porous polymers by co-assembly of stimuli responsive polymers
Torabi et al. Chitosan and functionalized acrylic nanoparticles as the precursor of new generation of bio-based antibacterial films
Frieß et al. Nanoporous block copolymer membranes with enhanced solvent resistance via UV‐mediated cross‐linking strategies
Ganguly et al. Synthesis of Mussel inspired polydopamine coated halloysite nanotubes based Semi‐IPN: an approach to fine tuning in drug release and mechanical toughening
KR20190058591A (ko) 백본에 광개시제기를 갖는 블록 폴리머 및 접착제 조성물에서의 그것의 용도
CA2926154C (en) New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same
Lin et al. An extremely simple method for fabricating 3D protein microarrays with an anti-fouling background and high protein capacity
JP2019019155A (ja) ナノカーボン分散液
Panic et al. Methacrylic acid based polymer networks with a high content of unfunctionalized nanosilica: Particle distribution, swelling, and rheological properties
Singh et al. Ultrasmall Sulfur‐Dots‐Mediated Facile Photopolymerization for the Production of Smart Injectable Ink for 3D Printing Applications
Ali et al. Preparation of Polymeric Core− Shell and Multilayer Nanoparticles: Surface-Initiated Polymerization Using in Situ Synthesized Photoiniferters
Gurgel et al. A Comprehensive Review on Core‐Shell Polymeric Particles for Enzyme Immobilization
CN107057046A (zh) 核壳杂化共聚物POSS‑(PDMAEMA‑b‑PDLA)8及其合成方法和应用
US20250129187A1 (en) Methods for synthesis of dye-labeled polymers
HK1225051B (zh) 用於连接和释放遗传物质,特别是dna/rna,的新型聚乙烯亚胺-基共聚物及其制备方法和用途
Chen et al. Polymeric vesicles with well-defined poly (methyl methacrylate)(PMMA) brushes via surface-initiated photopolymerization (SIPP)
RU2739986C2 (ru) Полая полимерная композиция
JP2014171924A (ja) 化学選択的接触還元用触媒、及びそれを用いる化学選択的接触還元方法
HK1225051A1 (en) New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular dna/rna, and method for the production and use of same

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190830

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 10TH ANNIV.) - STANDARD

Year of fee payment: 10

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20240923

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20240923

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20240923

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20251001

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20251001