CA2910766C - Dry powder formulations and methods of use - Google Patents
Dry powder formulations and methods of use Download PDFInfo
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- CA2910766C CA2910766C CA2910766A CA2910766A CA2910766C CA 2910766 C CA2910766 C CA 2910766C CA 2910766 A CA2910766 A CA 2910766A CA 2910766 A CA2910766 A CA 2910766A CA 2910766 C CA2910766 C CA 2910766C
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201361817435P | 2013-04-30 | 2013-04-30 | |
| US61/817,435 | 2013-04-30 | ||
| PCT/US2013/051895 WO2014178891A1 (en) | 2013-04-30 | 2013-07-24 | Dry powder formulations and methods of use |
Publications (2)
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| CA2910766A1 CA2910766A1 (en) | 2014-11-06 |
| CA2910766C true CA2910766C (en) | 2020-12-15 |
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| CA2910766A Active CA2910766C (en) | 2013-04-30 | 2013-07-24 | Dry powder formulations and methods of use |
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| EP (2) | EP3607941A1 (enExample) |
| JP (4) | JP2016518388A (enExample) |
| CN (1) | CN105473133A (enExample) |
| AU (1) | AU2013388034B2 (enExample) |
| CA (1) | CA2910766C (enExample) |
| HK (2) | HK1218720A1 (enExample) |
| WO (1) | WO2014178891A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| JP2016518388A (ja) | 2013-04-30 | 2016-06-23 | オティトピック インク． | 乾燥粉末配合および使用方法 |
| PL3107548T3 (pl) * | 2014-02-20 | 2022-10-31 | Otitopic Inc. | Suche formulacje w proszku do inhalacji |
| CN116687887A (zh) | 2014-07-31 | 2023-09-05 | 维克图拉公司 | 用于吸入的干粉制剂 |
| WO2017100656A1 (en) * | 2015-12-11 | 2017-06-15 | Otitopic Inc. | Dry powder formulations of aspirin for inhalation |
| AU2016378478B2 (en) * | 2015-12-22 | 2021-11-25 | Aspiair Gmbh | Treatment of moderate to severe influenza |
| EP3463378A4 (en) | 2016-06-03 | 2020-01-08 | Otitopic Inc. | DRY POWDER FORMULAS FOR INHALATION |
| CN110996965A (zh) | 2017-05-30 | 2020-04-10 | 罗山制药股份有限公司 | 稳定、无菌和结晶的邻乙酰水杨酸(阿司匹林)的小瓶内沉积物 |
| US10786456B2 (en) | 2017-09-22 | 2020-09-29 | Otitopic Inc. | Inhaled aspirin and magnesium to treat inflammation |
| AU2017432640B2 (en) | 2017-09-22 | 2023-11-30 | Aspeya US Inc. | Dry powder compositions with magnesium stearate |
| US12397004B2 (en) | 2018-11-05 | 2025-08-26 | Rush University Medical Center | Nasal delivery of low-dose aspirin for the treatment of neurodegenerative and lysosomal storage diseases |
| US11844792B2 (en) | 2020-07-10 | 2023-12-19 | Sean Downing | Treatment for severe acute respiratory illness associated with coronavirus |
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| US2293359A (en) * | 1941-01-08 | 1942-08-18 | Quisling Sverre | Acetyl salicylic acid preparation |
| FR2224175B1 (enExample) | 1973-04-04 | 1978-04-14 | Isf Spa | |
| US4069819A (en) | 1973-04-13 | 1978-01-24 | Societa Farmaceutici S.P.A. | Inhalation device |
| BR8007911A (pt) | 1979-12-06 | 1981-06-16 | Glaxo Group Ltd | Inalador aperfeicoado |
| US4375468A (en) | 1981-07-13 | 1983-03-01 | Verex Laboratories, Inc. | Constant order release aspirin composition and method of treating arthritis |
| US4885287A (en) | 1988-08-09 | 1989-12-05 | University Of Kentucky Research Foundation | Novel method of administering aspirin and dosage forms containing same |
| US5511726A (en) | 1988-09-23 | 1996-04-30 | Battelle Memorial Institute | Nebulizer device |
| IT1228459B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore con svuotamento regolare e completo della capsula. |
| DE69229070T2 (de) * | 1991-02-09 | 1999-11-18 | B.S.D. Bio Science Development Snc Di Omini C. & Zuccari G., Bussero | Antireaktive antiasthmatische Wirkung von Acetylsalicylsäure durch Inhalation |
| EP0499142A3 (en) | 1991-02-09 | 1993-05-05 | Hoechst Aktiengesellschaft | Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non steroidal anti-flammatory drugs |
| US5256538A (en) * | 1991-03-08 | 1993-10-26 | Board Of Regents, The University Of Texas System | Detection of early platelet activation and prediagnosis of thrombotic events |
| US5993805A (en) | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
| US5327883A (en) | 1991-05-20 | 1994-07-12 | Dura Pharmaceuticals, Inc. | Apparatus for aerosolizing powdered medicine and process and using |
| GB2265845B (en) | 1991-11-12 | 1996-05-01 | Medix Ltd | A nebuliser and nebuliser control system |
| US5639441A (en) | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
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| US5724957A (en) | 1993-01-29 | 1998-03-10 | Aradigm Corporation | Intrapulmonary delivery of narcotics |
| US20070117862A1 (en) | 1993-02-22 | 2007-05-24 | Desai Neil P | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US5506203C1 (en) | 1993-06-24 | 2001-02-06 | Astra Ab | Systemic administration of a therapeutic preparation |
| TW402506B (en) | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| PT101450B (pt) | 1994-02-02 | 1999-11-30 | Hovione Produtos Farmaceuticos | Novo dispositivo para inalacao |
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
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| US6209538B1 (en) | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
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-
2013
- 2013-07-24 JP JP2016511717A patent/JP2016518388A/ja active Pending
- 2013-07-24 EP EP19154878.3A patent/EP3607941A1/en active Pending
- 2013-07-24 CA CA2910766A patent/CA2910766C/en active Active
- 2013-07-24 AU AU2013388034A patent/AU2013388034B2/en active Active
- 2013-07-24 HK HK16106773.2A patent/HK1218720A1/zh unknown
- 2013-07-24 CN CN201380077562.XA patent/CN105473133A/zh active Pending
- 2013-07-24 EP EP13745533.3A patent/EP2991634A1/en not_active Withdrawn
- 2013-07-24 HK HK16106840.1A patent/HK1218855A1/zh unknown
- 2013-07-24 US US13/949,862 patent/US10149823B2/en active Active
- 2013-07-24 WO PCT/US2013/051895 patent/WO2014178891A1/en not_active Ceased
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2018
- 2018-12-11 US US16/216,924 patent/US11865210B2/en active Active
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2019
- 2019-02-27 JP JP2019034152A patent/JP2019089843A/ja active Pending
- 2019-04-26 US US16/396,272 patent/US11819569B2/en active Active
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2021
- 2021-03-06 JP JP2021035890A patent/JP7623854B2/ja active Active
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2023
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|---|---|
| US10149823B2 (en) | 2018-12-11 |
| CA2910766A1 (en) | 2014-11-06 |
| HK1218720A1 (zh) | 2017-03-10 |
| JP2023086774A (ja) | 2023-06-22 |
| US20190247304A1 (en) | 2019-08-15 |
| HK1218855A1 (zh) | 2017-03-17 |
| AU2013388034B2 (en) | 2019-08-15 |
| JP7623854B2 (ja) | 2025-01-29 |
| US11865210B2 (en) | 2024-01-09 |
| WO2014178891A1 (en) | 2014-11-06 |
| JP2016518388A (ja) | 2016-06-23 |
| JP2019089843A (ja) | 2019-06-13 |
| EP2991634A1 (en) | 2016-03-09 |
| US20190105267A1 (en) | 2019-04-11 |
| US20140322328A1 (en) | 2014-10-30 |
| CN105473133A (zh) | 2016-04-06 |
| EP3607941A1 (en) | 2020-02-12 |
| US11819569B2 (en) | 2023-11-21 |
| JP2021102620A (ja) | 2021-07-15 |
| AU2013388034A1 (en) | 2015-11-12 |
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