CA2863523A1 - Recombinant adenovirus expressing cancer antigens - Google Patents
Recombinant adenovirus expressing cancer antigens Download PDFInfo
- Publication number
- CA2863523A1 CA2863523A1 CA2863523A CA2863523A CA2863523A1 CA 2863523 A1 CA2863523 A1 CA 2863523A1 CA 2863523 A CA2863523 A CA 2863523A CA 2863523 A CA2863523 A CA 2863523A CA 2863523 A1 CA2863523 A1 CA 2863523A1
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- Prior art keywords
- adenovirus
- nucleic acid
- cancer
- immunogenic peptide
- heterologous nucleic
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261594005P | 2012-02-02 | 2012-02-02 | |
| US61/594,005 | 2012-02-02 | ||
| PCT/US2013/024506 WO2013116778A2 (en) | 2012-02-02 | 2013-02-01 | Immunogenic adenovirus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2863523A1 true CA2863523A1 (en) | 2013-08-08 |
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| CA2863523A Abandoned CA2863523A1 (en) | 2012-02-02 | 2013-02-01 | Recombinant adenovirus expressing cancer antigens |
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| CA (1) | CA2863523A1 (enExample) |
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| SG (3) | SG10201913795TA (enExample) |
| WO (1) | WO2013116778A2 (enExample) |
| ZA (1) | ZA201405755B (enExample) |
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| US9605276B2 (en) | 2012-08-24 | 2017-03-28 | Etubics Corporation | Replication defective adenovirus vector in vaccination |
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| CN104328140B (zh) * | 2014-10-08 | 2018-06-05 | 兰州大学 | 一种高嗜性膀胱癌靶向性肿瘤杀伤腺病毒 |
| EP3256140B1 (en) | 2015-01-09 | 2020-04-01 | Etubics Corporation | Compositions for ebola virus vaccination |
| JP6647315B2 (ja) | 2015-01-09 | 2020-02-14 | イーチュービクス コーポレイション | 組み合わせ免疫療法のための方法および組成物 |
| CN104762269A (zh) * | 2015-03-18 | 2015-07-08 | 红土生物技术有限公司 | 一种增强肿瘤抗原免疫原性的新策略及其在肺癌免疫治疗中的应用 |
| EP3286213B1 (en) * | 2015-04-20 | 2021-08-04 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| ES2987442T3 (es) * | 2015-05-04 | 2024-11-14 | Theriva Biologics S L | Adenovirus oncolíticos con mutaciones en epítopos de adenovirus inmunodominantes y su uso en el tratamiento del cáncer |
| CN105087647B (zh) * | 2015-06-17 | 2018-10-02 | 深圳益世康宁生物科技有限公司 | 一种携带Survivin抗原基因的重组腺相关病毒载体及其构建方法与应用 |
| CN105087648B (zh) * | 2015-06-17 | 2018-05-25 | 深圳益世康宁生物科技有限公司 | 携带mage-a3抗原基因的重组腺相关病毒载体及构建方法与应用 |
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| FI127460B (en) * | 2016-01-15 | 2018-06-29 | Targovax Oy | Combining adenovirus and chemotherapeutic agents for treating cancer |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| JP7015551B2 (ja) * | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| CN105779480B (zh) * | 2016-03-24 | 2020-03-20 | 成都康景生物科技有限公司 | 一种携带多位点突变型egfr新抗原基因的重组腺相关病毒载体及构建方法和应用 |
| CN117534735A (zh) * | 2016-03-31 | 2024-02-09 | 欧洲分子生物学实验室 | 腺病毒外壳蛋白衍生递送载体 |
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| CA3045892A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| KR20190098215A (ko) * | 2016-12-21 | 2019-08-21 | 멤젠 엘엘씨 | 무장된 복제-가능 종양 분해 아데노바이러스 |
| SG11201906973TA (en) * | 2017-01-30 | 2019-08-27 | Epicentrx Inc | Multiple transgene recombinant adenovirus |
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| CN112004923A (zh) | 2017-11-22 | 2020-11-27 | 迈索布拉斯特国际有限公司 | 细胞组合物及治疗方法 |
| GB201804468D0 (en) | 2018-03-21 | 2018-05-02 | Valo Therapeutics Oy | PeptiCRAd Cancer Therapy |
| BR112020019942A2 (pt) | 2018-04-09 | 2021-01-26 | Salk Institute For Biological Studies | composições de adenovírus oncolítico com propriedades de replicação aprimoradas |
| WO2019237371A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | 定点插入 ct1.1 基因的 cho 细胞株的构建方法及其用途 |
| CN109081873B (zh) * | 2018-08-10 | 2022-04-22 | 固安鼎泰海规生物科技有限公司 | 一种抗肿瘤重组nmm融合抗原质粒dna疫苗 |
| US20210340279A1 (en) | 2018-08-31 | 2021-11-04 | Yale University | Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators |
| CN110684800B (zh) * | 2018-11-02 | 2020-11-03 | 深圳益世康宁生物科技有限公司 | 一种携带肿瘤-睾丸抗原10基因的重组腺相关病毒载体及其应用价值 |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| WO2020259189A1 (zh) * | 2019-06-27 | 2020-12-30 | 北京太东生物科技有限公司 | Sox11作为精神分裂症诊断标记物的应用 |
| CA3149478A1 (en) | 2019-08-05 | 2021-02-11 | Mesoblast International Sarl | Cellular compositions comprising viral vectors and methods of treatment |
| EP3812465A1 (en) * | 2019-10-21 | 2021-04-28 | Universität Ulm | Adenovirus comprising a modified adenovirus hexon protein |
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| CN111850041A (zh) * | 2020-07-30 | 2020-10-30 | 药鼎(北京)国际细胞医学技术有限公司 | 一种治疗肝癌的含il12双顺反子的病毒构建体及其用途和构建方法 |
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2013
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2014
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| US11155599B2 (en) | 2021-10-26 |
| HK1205182A1 (en) | 2015-12-11 |
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| AU2013214776A1 (en) | 2014-08-21 |
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| AU2013214776B2 (en) | 2017-11-09 |
| ZA201405755B (en) | 2020-05-27 |
| CN104271748B9 (zh) | 2019-05-24 |
| DK2809788T3 (da) | 2019-12-09 |
| KR102100092B1 (ko) | 2020-04-13 |
| WO2013116778A3 (en) | 2013-12-19 |
| BR112014019049A2 (pt) | 2017-07-04 |
| US20140377294A1 (en) | 2014-12-25 |
| CN110042086A (zh) | 2019-07-23 |
| SG10201913795TA (en) | 2020-03-30 |
| EP2809788A2 (en) | 2014-12-10 |
| KR20140125834A (ko) | 2014-10-29 |
| WO2013116778A2 (en) | 2013-08-08 |
| JP6325459B2 (ja) | 2018-05-16 |
| JP2015506704A (ja) | 2015-03-05 |
| CN104271748A (zh) | 2015-01-07 |
| NZ628213A (en) | 2016-10-28 |
| CN104271748B (zh) | 2019-03-29 |
| SG10201606356YA (en) | 2016-09-29 |
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